Bruguiera sexangula var.rhynchopetala

• Index
• Plant Species
• Metabolite list (14)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Bruguiera sexangula var.rhynchopetala
Genus	Bruguiera
Family	Rhizophoraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Bruguiera
Linked NCBI taxonomy ID	39983
Linked level	genus

Family

Family in NCBI taxonomy	Rhizophoraceae
ID	40029

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (14)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005737	Myricetin 3-rutinoside / Myricetin-3-O-rutinoside					No. 1	No. 15
C00005169	Nicotiflorin / Nicotifloroside / Kaempferol 3-O-rutinoside / Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside / (-)-Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside	CHEMBL431610 CHEMBL79790 CHEMBL255020 CHEMBL501550 CHEMBL498879 CHEMBL1419228 CHEMBL1875691		22 / 10 / 12		No. 1	No. 15
C00005413	Rutin / Birutan / 3-Rutinosylquercetin / Quercetin 3-O-rutinoside / (+)-Quercetin 3-O-rutinoside / Quercetin 3-O-beta-rutinoside / (+)-Quercetin 3-O-beta-rutinoside / 3,3',4',5,7-Pentahydroxyflavone 3-rutinoside / Quercetin 3-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside	CHEMBL32579 CHEMBL310754 CHEMBL182108 CHEMBL226335 CHEMBL502782 CHEMBL1436093 CHEMBL1532989	D012431	25 / 18 / 16	29 / 8	No. 1	No. 15
C00004444	Tricin 7-glucoside / Tricin 7-O-glucoside / Tricin 7-O-beta-D-glucopyranoside					No. 2	No. 15
C00031169	Rhyncoside D / (-)-Rhyncoside D					No. 128	No. 72
C00031168	Rhyncoside C / (-)-Rhyncoside C					No. 128	No. 72
C00031167	Rhyncoside B / (-)-Rhyncoside B					No. 128	No. 72
C00031166	Rhyncoside A					No. 128	No. 72
C00030699	Lyoniside / (+)-Lyoniside	CHEMBL466738 CHEMBL583884				No. 174	No. 22
C00030465	Hedyotisol C	CHEMBL388779 CHEMBL1761832				No. 907
C00030464	Hedyotisol B	CHEMBL388779 CHEMBL1761832				No. 907
C00030463	Hedyotisol A	CHEMBL388779 CHEMBL1761832				No. 907
C00031170	Rhyncoside E					No. 907
C00031171	Rhyncoside F					No. 907

Human Protein / Gene in interactions

41 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P06746	DNA polymerase beta	Enzyme	C00005169 C00005413	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00005169 C00005413	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00005169 C00005413	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00005169 C00005413	1 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00005169 C00005413	1 / 1
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00005169 C00005413	1 / 1
P14679	Tyrosinase	Oxidoreductase	C00005413	4 / 2
P33527	Multidrug resistance-associated protein 1	drugs	C00005413	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00005413	0 / 0
P07237	Protein disulfide-isomerase	Enzyme	C00005169	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00005413	0 / 3
P11388	DNA topoisomerase 2-alpha	Isomerase	C00005413	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00005169	2 / 3
P39748	Flap endonuclease 1	Enzyme	C00005169	0 / 0
O75496	Geminin	Unclassified protein	C00005169	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00005413	0 / 0
P27487	Dipeptidyl peptidase 4	S9B	C00005413	0 / 1
Q9Y253	DNA polymerase eta	Enzyme	C00005169	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00005169	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00005413	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00005169	0 / 0
P06276	Cholinesterase	Hydrolase	C00005413	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00005413	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00005413	3 / 3
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00005413	2 / 0
P03372	Estrogen receptor	NR3A1	C00005413	1 / 1
P22303	Acetylcholinesterase	Hydrolase	C00005413	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00005413	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00005169	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00005169	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00005169	1 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00005413	4 / 3
P48147	Prolyl endopeptidase	S9A	C00005413	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00005169	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00005413	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00005169	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00005413	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00005169	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00005169	1 / 4
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00005169	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00005169	2 / 1

29 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
177	AGER, RAGE	advanced glycosylation end product-specific receptor	C00005413
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00005413
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00005413
581	BAX, BCL2L4	BCL2-associated X protein	C00005413
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00005413
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00005413
847	CAT	catalase (EC:1.11.1.6)	C00005413
873	CBR1, CBR, SDR21C1, hCBR1	carbonyl reductase 1 (EC:1.1.1.189 1.1.1.197 1.1.1.184)	C00005413
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00005413
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00005413
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00005413
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00005413
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00005413
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00005413
3458	IFNG, IFG, IFI	interferon, gamma	C00005413
3480	IGF1R, CD221, IGFIR, IGFR, JTK13	insulin-like growth factor 1 receptor (EC:2.7.10.1)	C00005413
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00005413
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00005413
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00005413
3667	IRS1, HIRS-1	insulin receptor substrate 1	C00005413
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00005413
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00005413
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00005413
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00005413
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00005413
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00005413
7039	TGFA, TFGA	transforming growth factor, alpha	C00005413
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00005413
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00005413

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions