| Organism name | Tupistra chinensis BAKER |
|---|---|
| Genus | Tupistra |
| Family | Convallariaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Tupistra |
|---|---|
| Linked NCBI taxonomy ID | 100497 |
| Linked level | genus |
| Family in NCBI taxonomy | Asparagaceae |
|---|---|
| ID | 40552 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00004567
|
Rhamnocitrin
/ 7-Methylkaempferol / 3,4',5-Trihydroxy-7-methoxyflavone / 3,5-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one |
CHEMBL442289
|
No. 3 | No. 15 |
|
|||
|
C00032430
|
Tupichinol E
|
No. 67 | No. 15 |
|
||||
|
C00032431
|
Tupichinol F
|
No. 67 | No. 15 |
|
||||
|
C00027459
|
Oxopurpureine
|
CHEMBL456295
|
20 / 27 / 24 | No. 74 |
|
|||
|
C00027457
|
Oxoglaucine
/ O-Methylatheroline |
CHEMBL470881
|
C111587
|
25 / 27 / 24 | No. 74 |
|
||
|
C00032429
|
Tupichinol D
/ (-)-Tupichinol D |
No. 179 | No. 15 |
|
||||
|
C00032428
|
Tupichilignan A
|
No. 223 | No. 21 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00027457 C00027459 | 1 / 2 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00027457 C00027459 | 4 / 3 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00027457 C00027459 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00027457 C00027459 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00027457 C00027459 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00027457 C00027459 | 2 / 2 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00027457 C00027459 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00027457 C00027459 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00027457 C00027459 | 11 / 10 |
| P42858 | Huntingtin | Unclassified protein | C00027457 C00027459 | 1 / 1 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00027457 C00027459 | 1 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00027457 C00027459 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00027457 | 1 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00027457 | 2 / 0 |
| Q92793 | CREB-binding protein | Enzyme | C00027457 | 1 / 1 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00027457 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00027457 | 0 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00027457 | 0 / 0 |
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00027459 | 1 / 4 |
| P29466 | Caspase-1 | C14 | C00027457 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00027457 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00027457 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00027457 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00027459 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00027459 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00027459 | 1 / 1 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00027459 | 4 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00027457 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00027457 | 0 / 0 |
| Q2TB90 | Putative hexokinase HKDC1 | Enzyme | C00027459 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00027459 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00027457 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00027459 | 1 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #180849 | Rubinstein-taybi syndrome 1; rsts1 |
Q92793
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
Q13315
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00094 | DNA repair defects |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00504 | Rubinstein-Taybi syndrome |
Q92793
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|