Species

KNApSAcK Entry

Organism name Pityrogramma tartarea
Genus Pityrogramma
Family Pteridaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Pityrogramma
Linked NCBI taxonomy ID 164273
Linked level genus

Family

Family in NCBI taxonomy Pteridaceae
ID 13819

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Euphyllophyta
ID 78536

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006955 External link 512 Gymnogrammene
No. 79
C00007943 External link 512 2',6'-Dihydroxy-3,4,4'-trimethoxydihydrochalcone
No. 90 No. 13
C00007939 External link 512 Calomelanone
No. 90 No. 13
C00006935 External link 512 Cardamomin
CHEMBL378104
13 / 18 / 14 No. 92 No. 13
C00006934 External link 512 Pinostrobin chalcone
/ 2',6'-Dihydroxy-4'-methoxychalcone
CHEMBL317221
CHEMBL1705800
3 / 1 / 2 No. 92 No. 13
C00006953 External link 512 Neosakuranetin
No. 92 No. 13
C00005078 External link 512 Calomelanol D
/ (-)-9,10-Dihydro-3,5-dihydroxy-2-(4-hydroxyphenyl)-10-phenyl-4H,8H-benzo[1,2-b:3,4-b']dipyran-4,8-dione
No. 620
C00007967 External link 512 Calomelanol D-1
No. 620

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00006935 0 / 0
Q99700 Ataxin-2 Unclassified protein C00006935 1 / 1
P22001 Potassium voltage-gated channel subfamily A member 3 KCNA, Kv1.x (Shaker) C00006935 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00006934 0 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00006935 2 / 0
O75496 Geminin Unclassified protein C00006935 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00006935 7 / 3
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00006935 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00006934 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00006935 0 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00006935 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00006935 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00006934 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00006935 4 / 3
O00255 Menin Unclassified protein C00006935 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00006935 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#166350 Osseous heteroplasia, progressive; poh P63092
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (16)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)