| Organism name | Penicillium lanosum |
|---|---|
| Genus | Penicillium |
| Family | Trichocomaceae |
| Kingdom | Fungi |
| Linked NCBI taxonomy name | Penicillium lanosum |
|---|---|
| Linked NCBI taxonomy ID | 357984 |
| Linked level | species |
| Family in NCBI taxonomy | Aspergillaceae |
|---|---|
| ID | 1131492 |
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00011297
|
Fumitremorgin B
|
C039286
|
No. 1307 |
|
||||
|
C00023720
|
Toluquinol
|
CHEMBL450917
|
C062397
|
No. 1546 |
|
|||
|
C00023719
|
p-Toluquinone
|
CHEMBL358225
|
C042889
|
1 / 0 / 0 | 1 / 0 | No. 6326 |
|
|
|
C00024000
|
Mycoin
/ Patulin / Clavitin / Tercinin / Leucopin / Clavicin / Expansion / Penicidin / Claviformin / 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one |
CHEMBL294018
|
D010365
|
21 / 26 / 48 | 23 / 2 | No. 7818 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00024000 | 7 / 37 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00024000 | 4 / 1 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00024000 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00024000 | 3 / 1 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00024000 | 0 / 0 |
| P06493 | Cyclin-dependent kinase 1 | Cdc2 | C00024000 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00024000 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00024000 | 0 / 0 |
| P14902 | Indoleamine 2,3-dioxygenase 1 | Enzyme | C00023719 | 0 / 0 |
| P23528 | Cofilin-1 | Unclassified protein | C00024000 | 0 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00024000 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00024000 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00024000 | 0 / 1 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00024000 | 5 / 3 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00024000 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00024000 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00024000 | 1 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00024000 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00024000 | 4 / 3 |
| P05412 | Transcription factor AP-1 | Transcription Factor | C00024000 | 0 / 0 |
| P35869 | Aryl hydrocarbon receptor | Transcription Factor | C00024000 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00024000 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00023719
|
| 467 | ATF3 | activating transcription factor 3 |
C00024000
|
| 10018 | BCL2L11, BAM, BIM, BOD | BCL2-like 11 (apoptosis facilitator) |
C00024000
|
| 637 | BID, FP497 | BH3 interacting domain death agonist |
C00024000
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00024000
|
| 9076 | CLDN1, CLD1, ILVASC, SEMP1 | claudin 1 |
C00024000
|
| 1365 | CLDN3, C7orf1, CPE-R2, CPETR2, HRVP1, RVP1 | claudin 3 |
C00024000
|
| 1364 | CLDN4, CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R | claudin 4 |
C00024000
|
| 1649 | DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 | DNA-damage-inducible transcript 3 |
C00024000
|
| 3458 | IFNG, IFG, IFI | interferon, gamma |
C00024000
|
| 3586 | IL10, CSIF, GVHDS, IL-10, IL10A, TGIF | interleukin 10 |
C00024000
|
| 3596 | IL13, IL-13, P600 | interleukin 13 |
C00024000
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00024000
|
| 3565 | IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 | interleukin 4 |
C00024000
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00024000
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00024000
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00024000
|
| 100506658 | OCLN, BLCPMG | occludin (EC:2.1.1.67) |
C00024000
|
| 5366 | PMAIP1, APR, NOXA | phorbol-12-myristate-13-acetate-induced protein 1 |
C00024000
|
| 23645 | PPP1R15A, GADD34 | protein phosphatase 1, regulatory subunit 15A |
C00024000
|
| 6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00024000
|
| 7082 | TJP1, ZO-1 | tight junction protein 1 |
C00024000
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00024000
|
| 7494 | XBP1, TREB5, XBP-1, XBP2 | X-box binding protein 1 |
C00024000
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| %606641 | Body mass index; bmi |
P37231
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
P37231
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #211980 | Lung cancer |
P04637
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #601665 | Obesity |
P37231
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
|
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|