Polygonum orientale

• Index
• Plant Species
• Metabolite list (9)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Polygonum orientale
Genus	Polygonum
Family	Polygonaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Persicaria orientalis
Linked NCBI taxonomy ID	467334
Linked level	species

Family

Family in NCBI taxonomy	Polygonaceae
ID	3615

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (9)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005071	3,5,8,3'-Tetramethoxy-6,7:4',5'-bis(methylenedioxy)flavone					No. 8	No. 15
C00005070	3'-Hydroxy-3,5,8,4',5'-pentamethoxy-6,7-methylenedioxyflavone					No. 8	No. 15
C00005069	5,3'-Dihydroxy-3,8,4',5'-tetramethoxy-6,7-methylenedioxyflavone					No. 8	No. 15
C00004867	Digicitrin	CHEMBL470677				No. 8	No. 15
C00004871	Exoticin					No. 8	No. 15
C00004869	3'-Hydroxy-3,5,6,7,8,4',5'-heptamethoxyflavone					No. 8	No. 15
C00001078	Lutexin / Orientin / Luteolin 8-C-beta-D-glucopyranoside / 8-beta-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone	CHEMBL520866 CHEMBL1468796	C065886	20 / 15 / 14		No. 22	No. 15
C00001055	Isoorientin / Homoorientin / Lespecapitioside / Luteolin 6-C-beta-D-glucopyranoside / 2-(3,4-Dihydroxyphenyl)-6-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one	CHEMBL239559 CHEMBL1302308	C057912	23 / 14 / 17	0 / 1	No. 22	No. 15
C00000609	(-)-Arctigenin	CHEMBL369142 CHEMBL435734 CHEMBL1966556	C071942	13 / 7 / 6		No. 223	No. 21

Human Protein / Gene in interactions

38 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9UNA4	DNA polymerase iota	Enzyme	C00000609 C00001055 C00001078	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001055 C00001078	0 / 0
O00255	Menin	Unclassified protein	C00001055 C00001078	2 / 5
Q99700	Ataxin-2	Unclassified protein	C00000609 C00001078	1 / 1
P06746	DNA polymerase beta	Enzyme	C00001055 C00001078	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00001055 C00001078	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001055 C00001078	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00001055 C00001078	1 / 1
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001055 C00001078	1 / 2
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001055 C00001078	1 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00001055 C00001078	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001055 C00001078	4 / 3
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001055 C00001078	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00001055 C00001078	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00001055 C00001078	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00001055 C00001078	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00001055 C00001078	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00000609	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000609	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000609	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001055	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000609	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000609	0 / 1
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00000609	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00000609	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000609	2 / 0
P39748	Flap endonuclease 1	Enzyme	C00001055	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00001078	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000609	0 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00001078	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00001078	3 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000609	1 / 0
Q02750	Dual specificity mitogen-activated protein kinase kinase 1	Ste7	C00000609	1 / 1
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001055	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001055	1 / 4
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001055	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00001055	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00001055	2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions