Cnicus benedictus
Species
KNApSAcK Entry
| Organism name | Cnicus benedictus |
|---|---|
| Genus | Cnicus |
| Family | Asteraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Centaurea benedicta |
|---|---|
| Linked NCBI taxonomy ID | 50282 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Natural Activity
List (37)
| Species | Activity |
|---|---|
| Cnicus benedictus L. | Allergenic |
| Cnicus benedictus L. | Analgesic |
| Cnicus benedictus L. | Antibacterial |
| Cnicus benedictus L. | Antidiarrheic |
| Cnicus benedictus L. | Antiedemic |
| Cnicus benedictus L. | Antigonadotropic |
| Cnicus benedictus L. | Antihemorrhagic |
| Cnicus benedictus L. | Antiinflammatory |
| Cnicus benedictus L. | Antileukemic |
| Cnicus benedictus L. | Antipyretic |
| Cnicus benedictus L. | Antiseptic |
| Cnicus benedictus L. | Antitumor |
| Cnicus benedictus L. | Aperitif |
| Cnicus benedictus L. | Astringent |
| Cnicus benedictus L. | Bitter |
| Cnicus benedictus L. | Carminative |
| Cnicus benedictus L. | Cholagogue |
| Cnicus benedictus L. | Choleretic |
| Cnicus benedictus L. | Contraceptive |
| Cnicus benedictus L. | Cytotoxic |
| Cnicus benedictus L. | Depurative |
| Cnicus benedictus L. | Diaphoretic |
| Cnicus benedictus L. | Diuretic |
| Cnicus benedictus L. | Emetic |
| Cnicus benedictus L. | Emmenagogue |
| Cnicus benedictus L. | Expectorant |
| Cnicus benedictus L. | Fibrinolytic |
| Cnicus benedictus L. | Gastrogogue |
| Cnicus benedictus L. | Hemostat |
| Cnicus benedictus L. | Lactagogue |
| Cnicus benedictus L. | Sialagogue |
| Cnicus benedictus L. | Stimulant |
| Cnicus benedictus L. | Stomachic |
| Cnicus benedictus L. | Swelling |
| Cnicus benedictus L. | Tonic |
| Cnicus benedictus L. | Uterosedative |
| Cnicus benedictus L. | Vermifuge |
Metabolite list (3)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003232
|
Cnicin
/ (+)-Cnicin |
CHEMBL1257707
|
C012849
|
3 / 4 / 2 | No. 60 | No. 38 |
|
|
|
C00003362
|
Salonitenolide
|
CHEMBL270061
|
C011103
|
No. 107 | No. 38 |
|
||
|
C00000609
|
(-)-Arctigenin
|
CHEMBL369142
CHEMBL435734 CHEMBL1966556 |
C071942
|
13 / 7 / 6 | No. 223 | No. 21 |
|
Human Protein / Gene in interactions
16 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000609 | 1 / 0 |
| Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | Ste7 | C00000609 | 1 / 1 |
| Q99700 | Ataxin-2 | Unclassified protein | C00000609 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000609 | 0 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000609 | 2 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00000609 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000609 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00003232 | 4 / 2 |
| P53582 | Methionine aminopeptidase 1 | M24A | C00003232 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000609 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000609 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00000609 | 1 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000609 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000609 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000609 | 0 / 0 |
| P50579 | Methionine aminopeptidase 2 | M24A | C00003232 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (11)
| OMIM | preferred title | UniProt |
|---|---|---|
| #615279 | Cardiofaciocutaneous syndrome 3; cfc3 |
Q02750
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601367 | Stroke, ischemic |
P00734
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
KEGG DISEASE (8)
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00523 | Noonan syndrome and related disorders |
Q02750
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|