| Organism name | Tripterygium wilfordii Hook F.(TwHF) |
|---|---|
| Genus | Tripterygium |
| Family | Celastraceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Tripterygium |
|---|---|
| Linked NCBI taxonomy ID | 123484 |
| Linked level | genus |
| Family in NCBI taxonomy | Celastraceae |
|---|---|
| ID | 4305 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00000627
|
(-)-Lirioresinol B
/ (-)-Syringaresinol |
CHEMBL361362
CHEMBL402653 |
1 / 0 / 0 | No. 38 | No. 21 |
|
||
|
C00034730
|
Tripterygiol
/ (+)-Tripterygiol |
No. 38 | No. 21 |
|
||||
|
C00013118
|
Euonine
/ Wilformine / (8alpha)-8-(Acetyloxy)-8-deoxoevonimine |
CHEMBL498972
CHEMBL443712 |
C062678
|
No. 43 |
|
|||
|
C00002637
|
Antiarol
/ 3,4,5-Trimethoxyphenol |
CHEMBL1319047
|
4 / 6 / 7 | No. 856 |
|
|||
|
C00034731
|
Triptriolide
|
No. 3698 | No. 41 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P11387 | DNA topoisomerase 1 | Isomerase | C00000627 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00002637 | 2 / 3 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00002637 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002637 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002637 | 4 / 3 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|