Platycladus orientalis
Species
KNApSAcK Entry
| Organism name | Platycladus orientalis |
|---|---|
| Genus | Platycladus |
| Family | Cupressaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Platycladus orientalis |
|---|---|
| Linked NCBI taxonomy ID | 58046 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Cupressaceae |
|---|---|
| ID | 3367 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Spermatophyta |
|---|---|
| ID | 58024 |
Natural Activity
List (13)
| Species | Activity |
|---|---|
| Platycladus orientalis (L.) Franco | Allergenic |
| Platycladus orientalis (L.) Franco | Antipyretic |
| Platycladus orientalis (L.) Franco | Aphrodisiac |
| Platycladus orientalis (L.) Franco | Astringent |
| Platycladus orientalis (L.) Franco | Cicatrizant |
| Platycladus orientalis (L.) Franco | Diuretic |
| Platycladus orientalis (L.) Franco | Emmenagogue |
| Platycladus orientalis (L.) Franco | Hemostat |
| Platycladus orientalis (L.) Franco | Orexigenic |
| Platycladus orientalis (L.) Franco | Propecic |
| Platycladus orientalis (L.) Franco | Stomachic |
| Platycladus orientalis (L.) Franco | Tonic |
| Platycladus orientalis (L.) Franco | toxic |
Metabolite list (11)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00032600
|
14,15,-Bisnor-8(17)-labdene-16,19-dioic acid
|
No. 143 |
|
|||||
|
C00022708
|
Isocupressic acid
/ (+)-Isocupressic acid / 15-Hydroxy-8(17),13E-labdadien-15-oic acid |
CHEMBL511193
|
C110793
|
No. 143 |
|
|||
|
C00022770
|
Pinusolidic acid
|
CHEMBL90504
CHEMBL465159 |
No. 143 |
|
||||
|
C00022722
|
13-Epicupressic acid
/ (+)-13-Epicupressic acid |
CHEMBL457163
|
No. 143 |
|
||||
|
C00031283
|
Sandaracopimaric acid
/ (-)-Sandaracopimaric acid |
CHEMBL513197
CHEMBL1397211 CHEMBL1410398 CHEMBL1735595 |
C082072
|
14 / 13 / 7 | No. 208 | No. 48 |
|
|
|
C00032668
|
6,7-Dehydrosandaracopimaric acid
/ (+)-6,7-Dehydrosandaracopimaric acid |
No. 208 | No. 48 |
|
||||
|
C00033527
|
13-Epitorulosol
/ epi-13-Torulosol |
CHEMBL596905
CHEMBL1521278 |
3 / 15 / 12 | No. 256 | No. 46 |
|
||
|
C00022771
|
Pinusolide
|
CHEMBL90271
CHEMBL425068 |
C101973
|
No. 294 |
|
|||
|
C00032365
|
Totaradiol
/ 3beta-Hydroxytotarol |
CHEMBL446064
|
No. 359 | No. 40 |
|
|||
|
C00022321
|
Lambertianic acid
|
CHEMBL463690
CHEMBL1982659 CHEMBL2048916 |
C421442
|
No. 408 |
|
|||
|
C00033539
|
1-Oxo-3beta-Hydroxytotarol
/ 3beta-Hydroxy-1-oxototarol |
No. 760 |
|
Human Protein / Gene in interactions
17 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q16637 | Survival motor neuron protein | Unclassified protein | C00033527 | 4 / 1 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00031283 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00033527 | 11 / 10 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00031283 | 0 / 1 |
| P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | C00031283 | 0 / 0 |
| P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | C00031283 | 1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00031283 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00031283 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00031283 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00031283 | 7 / 3 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00031283 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00031283 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00031283 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00033527 | 0 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00031283 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00031283 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00031283 | 1 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (28)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 |
P14867
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (19)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00808 | Idiopathic generalized epilepsies (IGEs) |
P14867
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|