Thalictrum fendleri Engelm.
Species
KNApSAcK Entry
| Organism name | Thalictrum fendleri Engelm. |
|---|---|
| Genus | Thalictrum |
| Family | Ranunculaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Thalictrum |
|---|---|
| Linked NCBI taxonomy ID | 46968 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Ranunculaceae |
|---|---|
| ID | 3440 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (5)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00029102
|
Thalidezine
/ Thalidesine |
No. 10 | No. 4 |
|
||||
|
C00027587
|
Preocoteine
|
No. 20 | No. 4 |
|
||||
|
C00026151
|
Tetrahydrothalifendine
/ (+/-)-Tetrahydrothalifendine |
CHEMBL1330951
CHEMBL1457510 CHEMBL2334880 |
29 / 18 / 14 | No. 37 | No. 4 |
|
||
|
C00026152
|
Thalidastine
|
No. 155 | No. 4 |
|
||||
|
C00026154
|
Thalifendine
|
CHEMBL1187148
|
C477156
|
No. 155 | No. 4 |
|
Human Protein / Gene in interactions
29 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00026151 | 1 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00026151 | 0 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00026151 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00026151 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00026151 | 1 / 1 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00026151 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00026151 | 0 / 1 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00026151 | 2 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00026151 | 2 / 2 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00026151 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00026151 | 0 / 0 |
| P11413 | Glucose-6-phosphate 1-dehydrogenase | Enzyme | C00026151 | 1 / 2 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00026151 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00026151 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00026151 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00026151 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00026151 | 3 / 3 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00026151 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00026151 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00026151 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00026151 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00026151 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00026151 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00026151 | 4 / 3 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00026151 | 1 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00026151 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00026151 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00026151 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00026151 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (18)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #103780 | Alcohol dependence |
P14416
|
| #300908 | Anemia, nonspherocytic hemolytic, due to g6pd deficiency |
P11413
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #159900 | Myoclonic dystonia |
P14416
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (14)
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00101 | Other phagocyte defects |
P11413
(related)
|
| H00668 | Anemia due to disorders of glutathione metabolism |
P11413
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|