Houttuynia cordata Thunb.

• Index
• Plant Species
• Metabolite list (10)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Houttuynia cordata Thunb.
Genus	Houttuynia
Family	Saururaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Houttuynia cordata
Linked NCBI taxonomy ID	16752
Linked level	species

Family

Family in NCBI taxonomy	Saururaceae
ID	16748

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Magnoliophyta
ID	3398

Metabolite list (10)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00030479	Hexadecanoic acid / n-Hexadecanoic acid	CHEMBL82293	D019308	16 / 8 / 8	35 / 1	No. 184	No. 68
C00000816	beta-Pinene	CHEMBL501351	C010789			No. 476	No. 35
C00000805	alpha-Pinene	CHEMBL442565	C005451	3 / 3 / 2	0 / 1	No. 476	No. 35
C00030758	2-Undecanone / Methyl nonyl ketone					No. 1611
C00003051	alpha-Phellandrene	CHEMBL455041	C005403			No. 1898	No. 35
C00000853	Myrcene	CHEMBL455491	C008574	3 / 3 / 3		No. 2285	No. 34
C00003029	Camphene	CHEMBL506889 CHEMBL510535	C019286			No. 2460	No. 35
C00000839	3-Carene	CHEMBL506854	C030218			No. 2690	No. 35
C00000861	Terpinolene	CHEMBL454697	C027009		1 / 0	No. 3725
C00029844	Bornyl acetate	CHEMBL1439452	C071528	4 / 1 / 4		No. 4140	No. 35

Human Protein / Gene in interactions

23 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P04150	Glucocorticoid receptor	NR3C1	C00000853 C00030479	0 / 1
Q96RI1	Bile acid receptor	NR1H4	C00000853 C00030479	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000805 C00000853	3 / 2
O60603	Toll-like receptor 2	Membrane receptor	C00030479	1 / 1
P05413	Fatty acid-binding protein, heart	Other cytosolic protein	C00030479	0 / 0
P08183	Multidrug resistance protein 1	drug	C00030479	1 / 0
P11387	DNA topoisomerase 1	Isomerase	C00030479	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00029844	0 / 0
O75496	Geminin	Unclassified protein	C00030479	0 / 0
P12104	Fatty acid-binding protein, intestinal	Other cytosolic protein	C00030479	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00030479	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00030479	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00030479	2 / 2
P15090	Fatty acid-binding protein, adipocyte	Other cytosolic protein	C00030479	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000805	0 / 0
Q01469	Fatty acid-binding protein, epidermal	Other cytosolic protein	C00030479	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000805	0 / 0
P03372	Estrogen receptor	NR3A1	C00030479	1 / 1
P10275	Androgen receptor	NR3C4	C00030479	3 / 4
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00030479	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00029844	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00029844	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00029844	1 / 4

35 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000861 C00030479
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00030479
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00030479
581	BAX, BCL2L4	BCL2-associated X protein	C00030479
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00030479
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00030479
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00030479
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00030479
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00030479
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00030479
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00030479
3034	HAL, HIS, HSTD	histidine ammonia-lyase (EC:4.3.1.3)	C00030479
57817	HAMP, HEPC, HFE2B, LEAP1, PLTR	hepcidin antimicrobial peptide	C00030479
3481	IGF2, C11orf43, IGF-II, PP9974	insulin-like growth factor 2 (somatomedin A)	C00030479
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00030479
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00030479
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00030479
9619	ABCG1, ABC8, WHITE1	ATP-binding cassette, sub-family G (WHITE), member 1	C00030479
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00030479
4493	MT1E, MT1, MTD	metallothionein 1E	C00030479
4494	MT1F, MT1	metallothionein 1F	C00030479
4496	MT1H, MT-0, MT-1H, MT-IH, MT1	metallothionein 1H	C00030479
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00030479
4502	MT2A, MT2	metallothionein 2A	C00030479
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00030479
3651	PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1	pancreatic and duodenal homeobox 1	C00030479
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00030479
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00030479
29893	PSMC3IP, GT198, HOP2, HUMGT198A, ODG3, TBPIP	PSMC3 interacting protein	C00030479
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00030479
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00030479
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00030479
23216	TBC1D1, TBC, TBC1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	C00030479
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00030479
7351	UCP2, BMIQ4, SLC25A8, UCPH	uncoupling protein 2 (mitochondrial, proton carrier)	C00030479

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions