Corbicula japonica

• Index
• Plant Species
• Metabolite list (42)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Corbicula japonica
Genus	Corbicula
Family	Corbiculidae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Corbicula japonica
Linked NCBI taxonomy ID	141464
Linked level	species

Family

Family in NCBI taxonomy	Corbiculidae
ID	45947

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Metazoa
ID	33208

Plant class

Plant class
ID

Metabolite list (42)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00000919	beta-Carotene	CHEMBL1293 CHEMBL1966639	D019207	7 / 12 / 11	104 / 19	No. 26	No. 59
C00000922	Canthaxanthin / beta-Carotene-4,4'-dione	CHEMBL1329004	D016644	4 / 4 / 3	0 / 1	No. 26	No. 59
C00000925	Myxoxanthine / beta-Echinenone		C105515			No. 26	No. 59
C00000931	Zeaxanthin / all-trans-Zeaxanthin	CHEMBL1357855 CHEMBL2359248	C005881	4 / 2 / 3	1 / 0	No. 26	No. 59
C00003765	alpha-Carotene					No. 26	No. 59
C00023232	7,8-Didehydro-beta,beta-caroten-3-ol					No. 26	No. 59
C00003776	Lutein / (all-E)-Lutein / all-trans-(+)-Xanthophyll / (3R,3'R,6'R)-beta,epsilon-Carotene-3,3'-diol	CHEMBL173929 CHEMBL172477 CHEMBL1559643 CHEMBL1979448	D014975	4 / 2 / 3	7 / 2	No. 26	No. 59
C00022834	Deoxylutein II / Anhydrolutein I	CHEMBL172328				No. 26	No. 59
C00022836	(3R,6'R)-7,8-Didehydro-beta,epsilon-caroten-3-ol					No. 26	No. 59
C00022862	Alloxanthin / Cynthiaxanthin / Pectenoxanthin / (3R,3'R)-7,7',8,8'-Tetradehydro-beta,beta-carotene-3,3'-diol		C006462			No. 26	No. 59
C00022863	Diatoxanthin / (3R,3'R)-7,8-Didehydro-beta,beta-carotene-3,3'-diol		C103105			No. 26	No. 59
C00022909	Pectenol A / (3S,3'R,4R)-7',8'-Didehydro-beta,beta-carotene-3,3',4-triol					No. 26	No. 59
C00022916	Loroxanthin / (3R,3'R,6'R)-beta,epsilon-Carotene-3,3',19-triol					No. 26	No. 59
C00023231	Isocryptoxanthin / beta,beta-Caroten-4-ol					No. 26	No. 59
C00023230	(6'R)-alpha-Echinenone					No. 26	No. 59
C00023234	(3S,3'S,4R,4'R)-Crustaxanthin					No. 26	No. 59
C00023033	Halocynthiaxanthin / (3S,3'R,5R,6S)-7',8'-Didehydro-5,6-epoxy-5,6,7,8-tetrahydro-8-oxo-beta,beta-carotene-3,3'-diol	CHEMBL450953	C073045			No. 114	No. 59
C00023240	Fucoxanthinol		C483031			No. 114	No. 59
C00003773	Fucoxanthin	CHEMBL1575074	C025164	12 / 17 / 46	6 / 3	No. 114	No. 59
C00023238	Diatoxanthin 3,6-epoxide					No. 114	No. 59
C00022925	Heteroxanthin / (3S,3'R,5R,6R)-7',8'-Didehydro-5,6-dihydro-3,3',5,6-tetrahydroxy-beta,beta-carotene					No. 114	No. 59
C00023237	6-Epiheteroxanthin					No. 114	No. 59
C00022955	Cycloviolaxanthin / (3S,3'S,5R,5'R,6R,6'R)-3,6:3',6'-Diepoxy-5,5',6,6'-tetrahydro-5,5'-dihydroxy-beta,beta-carotene					No. 114	No. 59
C00023166	Crassostreaxanthin A					No. 262	No. 59
C00023236	Corbiculaxanthin 3'-acetate					No. 664	No. 59
C00023235	Corbiculaxanthin					No. 664	No. 59
C00023239	Diadinochrome					No. 664	No. 59
C00023233	7',8'-Didehydrodeepoxyneoxanthin					No. 664	No. 59
C00022950	Mutatoxanthin / (3S,3'R,5R)-5,8-Epoxy-5,8-dihydro-beta,beta-carotene-3,3'-diol					No. 664	No. 59
C00023163	Peridininol					No. 782
C00023246	Pyrrhoxanthinol 5,8-furanoxide					No. 782
C00023244	Peridininol 5,8-furanoxide					No. 782
C00023245	Pyrrhoxanthin 5,8-furanoxide					No. 782
C00023162	Pyrrhoxanthin					No. 782
C00023161	Pyrrhoxanthinol					No. 782
C00023241	Peridinin / Sulcatoxanthin	CHEMBL1980535	C016040			No. 782
C00023242	Peridinin 5,8-furanoxide					No. 782
C00023243	Hydratoperidinin					No. 782
C00023247	Cyclopyrrhoxanthin					No. 782
C00023173	beta-Carotenone					No. 2278
C00023169	Semi-alpha-carotenone					No. 2278
C00023168	Semi-beta-carotenone					No. 2278

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00000919 C00000931 C00003773 C00003776	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000922 C00000931 C00003776	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000931 C00003773 C00003776	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000931 C00003773 C00003776	2 / 3
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000919 C00003773	0 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00000922 C00003773	4 / 3
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00000919 C00000922	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00003773	7 / 37
P00352	Retinal dehydrogenase 1	Enzyme	C00000919	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00003773	2 / 0
P06280	Alpha-galactosidase A	Enzyme	C00003773	1 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000922	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000919	11 / 10
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00003773	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00003773	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00003773	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00003773	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000919	1 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000919	0 / 0

115 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00003773 C00003776
581	BAX, BCL2L4	BCL2-associated X protein	C00000919 C00003776
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000919 C00003773
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00000919
2697	GJA1, AVSD3, CMDR, CX43, DFNB38, GJAL, HLHS1, HSS, ODDD	gap junction protein, alpha 1, 43kDa	C00003773
2705	GJB1, CMTX, CMTX1, CX32	gap junction protein, beta 1, 32kDa	C00003773
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00003773
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00000931
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00003776
847	CAT	catalase (EC:1.11.1.6)	C00003776
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00003776
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00003776
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00003776
124	ADH1A, ADH1	alcohol dehydrogenase 1A (class I), alpha polypeptide (EC:1.1.1.1)	C00000919
128	ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR	alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284)	C00000919
221	ALDH3B1, ALDH4, ALDH7	aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5)	C00000919
8659	ALDH4A1, ALDH4, P5CD, P5CDh	aldehyde dehydrogenase 4 family, member A1 (EC:1.2.1.88)	C00000919
287	ANK2, ANK-2, LQT4, brank-2	ankyrin 2, neuronal	C00000919
288	ANK3, ANKYRIN-G, MRT37	ankyrin 3, node of Ranvier (ankyrin G)	C00000919
427	ASAH1, AC, ACDase, ASAH, PHP, PHP32, SMAPME	N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23)	C00000919
51665	ASB1, ASB-1	ankyrin repeat and SOCS box containing 1	C00000919
140462	ASB9	ankyrin repeat and SOCS box containing 9	C00000919
9531	BAG3, BAG-3, BIS, CAIR-1, MFM6	BCL2-associated athanogene 3	C00000919
9530	BAG4, BAG-4, SODD	BCL2-associated athanogene 4	C00000919
9529	BAG5, BAG-5	BCL2-associated athanogene 5	C00000919
53630	BCMO1, BCDO, BCDO1, BCMO, BCO, BCO1	beta-carotene 15,15'-monooxygenase 1 (EC:1.14.99.36)	C00000919
999	CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO	cadherin 1, type 1, E-cadherin (epithelial)	C00000919
8837	CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS	CASP8 and FADD-like apoptosis regulator	C00000919
9071	CLDN10, CPETRL3, OSP-L	claudin 10	C00000919
51208	CLDN18, SFTA5, SFTPJ	claudin 18	C00000919
1277	COL1A1, OI4	collagen, type I, alpha 1	C00000919
1282	COL4A1, HANAC, ICH, POREN1, arresten	collagen, type IV, alpha 1	C00000919
1284	COL4A2, ICH, POREN2	collagen, type IV, alpha 2	C00000919
8738	CRADD, MRT34, RAIDD	CASP2 and RIPK1 domain containing adaptor with death domain	C00000919
1508	CTSB, APPS, CPSB	cathepsin B (EC:3.4.22.1)	C00000919
6387	CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B	chemokine (C-X-C motif) ligand 12	C00000919
6372	CXCL6, CKA-3, GCP-2, GCP2, SCYB6	chemokine (C-X-C motif) ligand 6	C00000919
4283	CXCL9, CMK, Humig, MIG, SCYB9, crg-10	chemokine (C-X-C motif) ligand 9	C00000919
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00000919
1592	CYP26A1, CP26, CYP26, P450RAI, P450RAI1	cytochrome P450, family 26, subfamily A, polypeptide 1 (EC:1.14.-.-)	C00000919
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000919
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000919
64816	CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43 (EC:1.14.14.1)	C00000919
1746	DLX2, TES-1, TES1	distal-less homeobox 2	C00000919
1748	DLX4, BP1, DLX7, DLX8, DLX9	distal-less homeobox 4	C00000919
2068	ERCC2, COFS2, EM9, TTD, XPD	excision repair cross-complementing rodent repair deficiency, complementation group 2 (EC:3.6.4.12)	C00000919
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000919
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000919
23017	FAIM2, LFG, LFG2, NGP35, NMP35, TMBIM2	Fas apoptotic inhibitory molecule 2	C00000919
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00000919
3169	FOXA1, HNF3A, TCF3A	forkhead box A1	C00000919
2627	GATA6	GATA binding protein 6	C00000919
2633	GBP1	guanylate binding protein 1, interferon-inducible	C00000919
81025	GJA9, CX58, CX59, GJA10	gap junction protein, alpha 9, 59kDa	C00000919
373156	GSTK1, GST, GST_13-13, GST13, GST13-13, GSTK1-1, hGSTK1	glutathione S-transferase kappa 1 (EC:2.5.1.18)	C00000919
2946	GSTM2, GST4, GSTM, GSTM2-2, GTHMUS	glutathione S-transferase mu 2 (muscle) (EC:2.5.1.18)	C00000919
2948	GSTM4, GSTM4-4, GTM4	glutathione S-transferase mu 4 (EC:2.5.1.18)	C00000919
2949	GSTM5, GSTM5-5, GTM5	glutathione S-transferase mu 5 (EC:2.5.1.18)	C00000919
2954	GSTZ1, GSTZ1-1, MAAI, MAI	glutathione S-transferase zeta 1 (EC:2.5.1.18 5.2.1.2)	C00000919
3204	HOXA7, ANTP, HOX1, HOX1.1, HOX1A	homeobox A7	C00000919
3216	HOXB6, HOX2, HOX2B, HU-2, Hox-2.2	homeobox B6	C00000919
3226	HOXC10, HOX3I	homeobox C10	C00000919
3448	IFNA14, IFN-alphaH, LEIF2H	interferon, alpha 14	C00000919
3449	IFNA16, IFN-alphaO	interferon, alpha 16	C00000919
3451	IFNA17, IFN-alphaI, IFNA, INFA, LEIF2C1	interferon, alpha 17	C00000919
3442	IFNA5, IFN-alpha-5, IFN-alphaG, INA5, INFA5, leIF_G	interferon, alpha 5	C00000919
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00000919
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00000919
3394	IRF8, H-ICSBP, ICSBP, ICSBP1, IRF-8	interferon regulatory factor 8	C00000919
50805	IRX4, IRXA3	iroquois homeobox 4	C00000919
3688	ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	C00000919
3691	ITGB4, CD104	integrin, beta 4	C00000919
3713	IVL	involucrin	C00000919
3875	KRT18, CYK18, K18	keratin 18	C00000919
3880	KRT19, CK19, K19, K1CS	keratin 19	C00000919
3849	KRT2, CK-2e, K2e, KRT2A, KRT2E, KRTE	keratin 2	C00000919
3855	KRT7, CK7, K2C7, K7, SCL	keratin 7	C00000919
3856	KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO	keratin 8	C00000919
8022	LHX3, CPHD3, LIM3, M2-LHX3	LIM homeobox 3	C00000919
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00000919
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00000919
4153	MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD	mannose-binding lectin (protein C) 2, soluble	C00000919
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00000919
4212	MEIS2, HsT18361, MRG1	Meis homeobox 2	C00000919
4222	MEOX1, KFS2, MOX1	mesenchyme homeobox 1	C00000919
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00003773
3110	MNX1, HB9, HLXB9, HOXHB9, SCRA1	motor neuron and pancreas homeobox 1	C00000919
4439	MSH5, G7, MUTSH5, NG23	mutS homolog 5	C00000919
4586	MUC5AC, MUC5, TBM, leB	mucin 5AC, oligomeric mucus/gel-forming	C00000919
4842	NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS	nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)	C00000919
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000919
4973	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1	oxidized low density lipoprotein (lectin-like) receptor 1	C00000919
5098	PCDHGC3, PC43, PCDH-GAMMA-C3, PCDH2	protocadherin gamma subfamily C, 3	C00000919
5359	PLSCR1, MMTRA1B	phospholipid scramblase 1	C00000919
57048	PLSCR3	phospholipid scramblase 3	C00000919
57088	PLSCR4, TRA1	phospholipid scramblase 4	C00000919
10635	RAD51AP1, PIR51	RAD51 associated protein 1	C00000919
5892	RAD51D, BROVCA4, R51H3, RAD51L3, TRAD	RAD51 paralog D	C00000919
5914	RARA, NR1B1, RAR	retinoic acid receptor, alpha	C00000919
5915	RARB, HAP, NR1B2, RRB2	retinoic acid receptor, beta	C00000919
5918	RARRES1, LXNL, TIG1	retinoic acid receptor responder (tazarotene induced) 1	C00000919
5950	RBP4, RDCCAS	retinol binding protein 4, plasma	C00000919
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00000919
949	SCARB1, CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1	scavenger receptor class B, member 1	C00000919
4990	SIX6, MCOPCT2, OPTX2, Six9	SIX homeobox 6	C00000919
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00000919
9517	SPTLC2, HSN1C, LCB2, LCB2A, NSAN1C, SPT2, hLCB2a	serine palmitoyltransferase, long chain base subunit 2 (EC:2.3.1.50)	C00000919
6720	SREBF1, SREBP-1c, SREBP1, bHLHd1	sterol regulatory element binding transcription factor 1	C00000919
7052	TGM2, G-ALPHA-h, GNAH, TG2, TGC	transglutaminase 2 (EC:2.3.2.13)	C00000919
7047	TGM4, TGP, hTGP	transglutaminase 4 (EC:2.3.2.13)	C00000919
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000919
3604	TNFRSF9, 4-1BB, CD137, CDw137, ILA	tumor necrosis factor receptor superfamily, member 9	C00000919
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00000919
10190	TXNDC9, APACD, PHLP3	thioredoxin domain containing 9	C00000919
7517	XRCC3, CMM6	X-ray repair complementing defective repair in Chinese hamster cells 3	C00000919

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions