| Organism name | Chaetomium chiversii |
|---|---|
| Genus | Chaetomium |
| Family | Chaetomiaceae |
| Kingdom | Fungi |
| Linked NCBI taxonomy name | Chaetomium chiversii |
|---|---|
| Linked NCBI taxonomy ID | 155873 |
| Linked level | species |
| Family in NCBI taxonomy | Chaetomiaceae |
|---|---|
| ID | 35718 |
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00039177
|
Eugenetin
|
No. 719 |
|
|||||
|
C00040142
|
Radicicol
/ (+)-Radicicol |
CHEMBL414883
CHEMBL453974 CHEMBL453386 CHEMBL1596863 |
C035359
|
44 / 27 / 24 | 6 / 0 | No. 981 |
|
|
|
C00038727
|
Chaetochiversin B
/ (+)-Chaetochiversin B |
No. 2234 |
|
|||||
|
C00038726
|
Chaetochiversin A
/ (+)-Chaetochiversin A |
No. 2234 |
|
|||||
|
C00038728
|
Chaetochromin A
|
CHEMBL162783
CHEMBL1099258 CHEMBL1096606 |
C032678
|
41 / 23 / 13 | No. 8470 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00038728 C00040142 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00038728 C00040142 | 1 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00038728 C00040142 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00038728 C00040142 | 1 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00038728 C00040142 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00038728 C00040142 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00038728 C00040142 | 4 / 3 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00038728 C00040142 | 1 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00038728 C00040142 | 1 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00038728 C00040142 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00038728 C00040142 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00038728 C00040142 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00038728 C00040142 | 1 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00038728 C00040142 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00038728 C00040142 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00038728 C00040142 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00038728 C00040142 | 2 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00038728 C00040142 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00038728 C00040142 | 2 / 3 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00038728 | 0 / 0 |
| Q13188 | Serine/threonine-protein kinase 3 | STE serine/threonine protein kinase MST subfamily | C00040142 | 0 / 0 |
| Q9NQU5 | Serine/threonine-protein kinase PAK 6 | STE serine/threonine protein kinase PAKB subfamily | C00040142 | 0 / 0 |
| P07332 | Tyrosine-protein kinase Fes/Fps | Fer | C00040142 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00038728 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00038728 | 0 / 0 |
| P16152 | Carbonyl reductase [NADPH] 1 | Enzyme | C00040142 | 0 / 0 |
| O00444 | Serine/threonine-protein kinase PLK4 | PLK serine/threonine protein kinase subfamily | C00040142 | 0 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00040142 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00038728 | 3 / 1 |
| P37840 | Alpha-synuclein | Unclassified protein | C00040142 | 4 / 2 |
| Q99683 | Mitogen-activated protein kinase kinase kinase 5 | Ste11 | C00040142 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00038728 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00038728 | 0 / 0 |
| O75828 | Carbonyl reductase [NADPH] 3 | Enzyme | C00040142 | 0 / 0 |
| P98073 | Enteropeptidase | Enzyme | C00038728 | 1 / 1 |
| Q16659 | Mitogen-activated protein kinase 6 | CMGC serine/threonine protein kinase ERK3 subfamily | C00040142 | 0 / 0 |
| P52564 | Dual specificity mitogen-activated protein kinase kinase 6 | Ste7 | C00040142 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00038728 | 0 / 0 |
| O14976 | Cyclin-G-associated kinase | NAK serine/threonine protein kinase subfamily | C00040142 | 0 / 0 |
| O94804 | Serine/threonine-protein kinase 10 | STE serine/threonine protein kinase SLK subfamily | C00040142 | 1 / 0 |
| P16298 | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform | Ser_Thr | C00038728 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00040142 | 2 / 2 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00038728 | 1 / 1 |
| Q9H2G2 | STE20-like serine/threonine-protein kinase | STE serine/threonine protein kinase SLK subfamily | C00040142 | 0 / 0 |
| P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00040142 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00038728 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00038728 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00038728 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00038728 | 0 / 0 |
| Q15759 | Mitogen-activated protein kinase 11 | p38 | C00040142 | 0 / 0 |
| Q96P20 | NACHT, LRR and PYD domains-containing protein 3 | Unclassified protein | C00040142 | 3 / 1 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00040142 | 0 / 3 |
| Q9HCP0 | Casein kinase I isoform gamma-1 | Ck1 | C00040142 | 0 / 0 |
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00040142 | 0 / 0 |
| Q86V86 | Serine/threonine-protein kinase pim-3 | Pim | C00040142 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00038728 | 2 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00038728 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00038728 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00038728 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00038728 | 1 / 1 |
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00038728 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00040142 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00040142 | 1 / 2 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00038728 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00038728 | 2 / 1 |
| Q9P1W9 | Serine/threonine-protein kinase pim-2 | Pim | C00040142 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00040142
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00040142
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00040142
|
| 3303 | HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1 | heat shock 70kDa protein 1A |
C00040142
|
| 3757 | KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1 | potassium voltage-gated channel, subfamily H (eag-related), member 2 |
C00040142
|
| 5241 | PGR, NR3C3, PR | progesterone receptor |
C00040142
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #607115 | Cinca syndrome; cinca |
Q96P20
|
| #114500 | Colorectal cancer; crc |
P84022
Q14191 |
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #226200 | Enterokinase deficiency |
P98073
|
| #120100 | Familial cold autoinflammatory syndrome 1; fcas1 |
Q96P20
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #191900 | Muckle-wells syndrome; mws |
Q96P20
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #273300 | Testicular germ cell tumor; tgct |
O94804
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00988 | Enterokinase deficiency |
P98073
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00282 | Cryopyrin associated periodic syndrome (CAPS) |
Q96P20
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|