| Organism name | Kandelia candel |
|---|---|
| Genus | Kandelia |
| Family | Rhizophoraceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Kandelia candel |
|---|---|
| Linked NCBI taxonomy ID | 61147 |
| Linked level | species |
| Family in NCBI taxonomy | Rhizophoraceae |
|---|---|
| ID | 40029 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00002906
|
Afzelechin-(4alpha->8)-afzelechin
|
No. 16 | No. 19 |
|
||||
|
C00009058
|
Afzelechin-(4alpha->8)-catechin
|
No. 16 | No. 19 |
|
||||
|
C00009186
|
Cinchonanin IIa
/ Cinchonain-1a-(4beta->8)-epicatechin |
CHEMBL491581
|
No. 29 | No. 19 |
|
|||
|
C00002929
|
Kandelin A1
/ Cinchonain-1a-(4beta->8)-catechin |
CHEMBL491581
|
No. 29 | No. 19 |
|
|||
|
C00009291
|
Cinnamtannin B1
|
CHEMBL540956
CHEMBL81478 CHEMBL445468 CHEMBL1213875 CHEMBL1213876 |
14 / 4 / 7 | No. 29 | No. 19 |
|
||
|
C00009098
|
Procyanidin C1
/ [Epicatechin-(4beta->8)]2-epicatechin |
CHEMBL290632
|
13 / 5 / 6 | No. 29 | No. 19 |
|
||
|
C00009087
|
Epicatechin-(4beta->6)-epicatechin-(4beta->8)-epicatechin
|
CHEMBL592228
|
2 / 3 / 4 | No. 29 | No. 19 |
|
||
|
C00009084
|
[Epicatechin-(4beta->6)]2-epicatechin
|
No. 29 | No. 19 |
|
||||
|
C00009086
|
Epicatechin-(4beta->6)-epicatechin-(4beta->8)-catechin
|
CHEMBL592228
|
2 / 3 / 4 | No. 29 | No. 19 |
|
||
|
C00000937
|
Afzelechin
|
CHEMBL159303
CHEMBL1326092 |
7 / 4 / 12 | No. 52 | No. 14 |
|
||
|
C00008817
|
Gallocatechin
/ (+)-Gallocatechin / (+)-Gallocatechol / (2R,3S)-3,4-Dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol |
CHEMBL47386
CHEMBL125743 CHEMBL130415 CHEMBL264167 CHEMBL404845 |
26 / 17 / 29 | No. 52 | No. 14 |
|
||
|
C00009188
|
Kandelin B4
/ Cinchonain-1b-(4beta->8)-epicatechin-(4beta->8)-catechin |
No. 113 | No. 19 |
|
||||
|
C00009101
|
Kandelin B3
|
No. 113 | No. 19 |
|
||||
|
C00009187
|
Kandelin B1
/ Cinchonain-1a-(4beta->8)-epicatechin-(4beta->8)-epicatechin |
No. 113 | No. 19 |
|
||||
|
C00008964
|
Cinchonain Ib
|
CHEMBL401058
CHEMBL251476 |
No. 444 |
|
||||
|
C00002913
|
Cinchonain Ia
|
CHEMBL401058
CHEMBL251476 |
No. 444 |
|
||||
|
C00038888
|
Cyclo-(Leu-Tyr)
/ (+)-Cyclo-(Leu-Tyr) |
No. 2431 |
|
|||||
|
C00038887
|
Cyclo-(Leu-Leu)
/ Cyclo(leucylleucine) |
C007199
|
No. 4490 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000937 C00008817 C00009291 | 0 / 3 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00009086 C00009087 C00009098 | 2 / 2 |
| P08253 | 72 kDa type IV collagenase | M10A | C00009086 C00009087 C00009098 | 1 / 3 |
| P24723 | Protein kinase C eta type | Eta | C00009098 C00009291 | 1 / 0 |
| P05771 | Protein kinase C beta type | Alpha | C00009098 C00009291 | 0 / 0 |
| P05129 | Protein kinase C gamma type | Alpha | C00009098 C00009291 | 1 / 1 |
| Q05655 | Protein kinase C delta type | Delta | C00009098 C00009291 | 0 / 0 |
| P41743 | Protein kinase C iota type | Iota | C00009098 C00009291 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00009098 C00009291 | 0 / 0 |
| O94806 | Serine/threonine-protein kinase D3 | Pkd | C00009098 C00009291 | 0 / 0 |
| Q02156 | Protein kinase C epsilon type | Eta | C00009098 C00009291 | 0 / 0 |
| Q04759 | Protein kinase C theta type | Delta | C00009098 C00009291 | 0 / 1 |
| Q05513 | Protein kinase C zeta type | Iota | C00009098 C00009291 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000937 C00008817 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000937 C00008817 | 0 / 0 |
| Q15139 | Serine/threonine-protein kinase D1 | Pkd | C00009098 C00009291 | 0 / 0 |
| P56817 | Beta-secretase 1 | A1A | C00008817 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00008817 | 3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00008817 | 2 / 2 |
| P00374 | Dihydrofolate reductase | Oxidoreductase | C00008817 | 1 / 1 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00008817 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00008817 | 0 / 0 |
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00008817 | 2 / 3 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00008817 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00008817 | 4 / 3 |
| P10415 | Apoptosis regulator Bcl-2 | Other cytosolic protein | C00008817 | 0 / 7 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00009291 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00008817 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00008817 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00008817 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00000937 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000937 | 1 / 2 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00008817 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00008817 | 1 / 4 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00008817 | 0 / 0 |
| Q9UM73 | ALK tyrosine kinase receptor | TKL serine/threonine protein kinase STKR type 1 subfamily | C00000937 | 1 / 1 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00008817 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00008817 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00008817 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00008817 | 2 / 3 |
| Q06187 | Tyrosine-protein kinase BTK | Tec | C00009291 | 2 / 2 |
| P02768 | Serum albumin | Secreted protein | C00008817 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00008817 | 1 / 1 |
| P52209 | 6-phosphogluconate dehydrogenase, decarboxylating | Enzyme | C00008817 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000937 | 0 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #300755 | Agammaglobulinemia, x-linked; xla |
Q06187
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #114550 | Hepatocellular carcinoma |
P08581
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #307200 | Isolated growth hormone deficiency, type iii; ighd3 |
Q06187
|
| #613839 | Megaloblastic anemia due to dihydrofolate reductase deficiency |
P00374
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #613014 | Neuroblastoma, susceptibility to, 3; nblst3 |
Q9UM73
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
| #605361 | Spinocerebellar ataxia 14; sca14 |
P05129
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601367 | Stroke, ischemic |
P24723
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278300 | Xanthinuria, type i |
P47989
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01197 | Dihydrofolate reductase (DHFR) deficiency |
P00374
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
P05129
(related)
Q9NUW8 (related) |
| H00025 | Penile cancer |
P08253
(related)
P14780 (related) P35354 (related) |
| H00028 | Choriocarcinoma |
P08253
(related)
P10415 (related) |
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00018 | Gastric cancer |
P08581
(related)
P10415 (related) |
| H00021 | Renal cell carcinoma |
P08581
(related)
|
| H00046 | Cholangiocarcinoma |
P08581
(related)
P35354 (related) |
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P10415
(related)
|
| H00013 | Small cell lung cancer |
P10415
(related)
|
| H00030 | Cervical cancer |
P10415
(related)
|
| H00041 | Kaposi's sarcoma |
P10415
(related)
|
| H00054 | Nasopharyngeal cancer |
P10415
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00408 | Type I diabetes mellitus |
Q04759
(related)
|
| H00085 | Agammaglobulinemias |
Q06187
(related)
|
| H00254 | Pituitary Dwarfism (PD) |
Q06187
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00014 | Non-small cell lung cancer |
Q9UM73
(related)
|