| Organism name | Macaranga conifera |
|---|---|
| Genus | Macaranga |
| Family | Euphorbiaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Macaranga conifera |
|---|---|
| Linked NCBI taxonomy ID | 109817 |
| Linked level | species |
| Family in NCBI taxonomy | Euphorbiaceae |
|---|---|
| ID | 3977 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00029441
|
20-Epibryonolic acid
|
CHEMBL482596
CHEMBL1982562 |
No. 13 | No. 51 |
|
|||
|
C00005010
|
Isolicoflavonol
/ 3,5,7-Trihydroxy-2-[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]-4H-1-benzopyran-4-one |
CHEMBL457679
|
5 / 5 / 3 | No. 15 | No. 15 |
|
||
|
C00000954
|
Senegalensein
/ Lonchocarpol A / 6,8-Diprenylnaringenin |
CHEMBL477969
CHEMBL1545584 |
C068505
|
16 / 26 / 18 | No. 19 | No. 14 |
|
|
|
C00014198
|
Tomentosanol D
/ 5,7,4'-Trihydroxy-8-(2-hydroxy-3-methylbutyl-3-enyl)flavanone |
CHEMBL443717
|
No. 28 | No. 14 |
|
|||
|
C00008245
|
8-Prenylnaringenin
/ Sophoraflavanone B / (-)-8-Prenylnaringenin |
CHEMBL376915
CHEMBL460647 |
10 / 8 / 4 | No. 28 | No. 14 |
|
||
|
C00008621
|
Lupinifolinol
|
CHEMBL559586
|
No. 39 |
|
||||
|
C00014231
|
5-Hydroxy-4'-methoxy-6'',6''-dimethylpyrano[2'',3'':7,8]flavanone
|
No. 127 | No. 14 |
|
||||
|
C00014212
|
Phellodensin D
/ 5,4'-Dihydroxy-2''-(1-hydroxy-1-methylethyl)dihydrofuro[2,3-h]flavanone |
No. 740 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O75496 | Geminin | Unclassified protein | C00000954 C00005010 C00008245 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000954 C00008245 | 1 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000954 C00008245 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000954 C00005010 | 2 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00005010 | 1 / 1 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00008245 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00008245 | 4 / 2 |
| P39748 | Flap endonuclease 1 | Enzyme | C00000954 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00000954 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00000954 | 1 / 1 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00008245 | 0 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000954 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000954 | 7 / 3 |
| P04062 | Glucosylceramidase | Enzyme | C00000954 | 6 / 4 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00005010 | 2 / 2 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00008245 | 2 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00008245 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00008245 | 1 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00005010 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00000954 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000954 | 4 / 3 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00000954 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00000954 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000954 | 1 / 2 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00008245 | 0 / 0 |
| P17861 | X-box-binding protein 1 | Unclassified protein | C00000954 | 1 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #612371 | Major affective disorder 7; mafd7 |
P17861
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|