PCIDB

KNApSAcK Metabolite C00008245

Metabolite

KNApSAcK Entry

id C00008245
Name 8-Prenylnaringenin / Sophoraflavanone B / (-)-8-Prenylnaringenin
CAS RN 53846-50-7
Standard InChI InChI=1S/C20H20O5/c1-11(2)3-8-14-15(22)9-16(23)19-17(24)10-18(25-20(14)19)12-4-6-13(21)7-5-12/h3-7,9,18,21-23H,8,10H2,1-2H3
Standard InChI (Main Layer) InChI=1S/C20H20O5/c1-11(2)3-8-14-15(22)9-16(23)19-17(24)10-18(25-20(14)19)12-4-6-13(21)7-5-12/h3-7,9,18,21-23H,8,10H2,1-2H3

Cluster

Phytochemical cluster No. 14
KCF-S cluster No. 28

Link

ChEMBL

By standard InChI CHEMBL460647
By standard InChI Main Layer CHEMBL376915 CHEMBL460647

KEGG

By LinkDB C18023

CTD

By CAS RN

Human Protein / Gene in interaction

10 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL460647 CHEMBL1794585 (1)
0 / 0
P37840 Alpha-synuclein Unclassified protein CHEMBL460647 CHEMBL2354282 (1)
4 / 2
O75496 Geminin Unclassified protein CHEMBL460647 CHEMBL2114843 (1)
0 / 0
Q92731 Estrogen receptor beta NR3A2 CHEMBL460647 CHEMBL909844 (1) CHEMBL909845 (1)
CHEMBL908817 (1)
0 / 1
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL460647 CHEMBL2114788 (1)
0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette CHEMBL376915 CHEMBL1694230 (1)
2 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A CHEMBL460647 CHEMBL998833 (1)
0 / 0
P03372 Estrogen receptor NR3A1 CHEMBL460647 CHEMBL909843 (1) CHEMBL909845 (1)
CHEMBL909846 (1)
1 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL460647 CHEMBL2114738 (1)
0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL460647 CHEMBL2354287 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614490 Blood group, junior system; jr Q9UNQ0
#127750 Dementia, lewy body; dlb P37840
#615363 Estrogen resistance; estrr P03372
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0

KEGG DISEASE (4)

KEGG disease name UniProt
H00026 Endometrial Cancer P03372 (marker)
Q92731 (marker)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)