Betula spp.

• Index
• Plant Species
• Natural Activity
• Metabolite list (9)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Betula spp.
Genus	Betula
Family	Betulaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Betula
Linked NCBI taxonomy ID	3504
Linked level	genus

Family

Family in NCBI taxonomy	Betulaceae
ID	3514

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Natural Activity

List (13)

Species	Activity
Betula spp.	Analgesic
Betula spp.	Antibacterial
Betula spp.	Antiinflammatory
Betula spp.	Antimelanomic
Betula spp.	Antipyretic
Betula spp.	Antiseptic
Betula spp.	Aquaretic
Betula spp.	Astringent
Betula spp.	Couterirritant
Betula spp.	Depurative
Betula spp.	Diuretic
Betula spp.	Parasiticide
Betula spp.	Saluretic

Metabolite list (9)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00009070	Procyanidin B6 / Catechin-(4alpha->6)-catechin	CHEMBL506487 CHEMBL502984 CHEMBL451115				No. 16	No. 19
C00008226	Naringenin 7,4'-dimethyl ether	CHEMBL462909 CHEMBL2164944				No. 25	No. 14
C00000999	Sakuranetin / Naringenin 7-O-methyl ether / 5,4'-Dihydroxy-7-methoxyflavanone	CHEMBL74852 CHEMBL448297	C099724	19 / 20 / 20		No. 25	No. 14
C00009089	Arecatannin B1	CHEMBL592329		2 / 3 / 4		No. 29	No. 19
C00009086	Epicatechin-(4beta->6)-epicatechin-(4beta->8)-catechin	CHEMBL592228		2 / 3 / 4		No. 29	No. 19
C00009091	Procyanidin C2	CHEMBL290632		13 / 5 / 6		No. 29	No. 19
C00009094	Catechin-(4alpha->8)-epicatechin-(4beta->8)-epicatechin	CHEMBL290632		13 / 5 / 6		No. 29	No. 19
C00009097	Arecatamnin A1 / [Epicatechin-(4beta->8)]2-catechin	CHEMBL290632		13 / 5 / 6		No. 29	No. 19
C00009098	Procyanidin C1 / [Epicatechin-(4beta->8)]2-epicatechin	CHEMBL290632		13 / 5 / 6		No. 29	No. 19

Human Protein / Gene in interactions

32 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P14780	Matrix metalloproteinase-9	M10A	C00009086 C00009089 C00009091 C00009094 C00009097 C00009098	2 / 2
P08253	72 kDa type IV collagenase	M10A	C00009086 C00009089 C00009091 C00009094 C00009097 C00009098	1 / 3
P41743	Protein kinase C iota type	Iota	C00009091 C00009094 C00009097 C00009098	0 / 0
P24723	Protein kinase C eta type	Eta	C00009091 C00009094 C00009097 C00009098	1 / 0
P05771	Protein kinase C beta type	Alpha	C00009091 C00009094 C00009097 C00009098	0 / 0
P05129	Protein kinase C gamma type	Alpha	C00009091 C00009094 C00009097 C00009098	1 / 1
Q15139	Serine/threonine-protein kinase D1	Pkd	C00009091 C00009094 C00009097 C00009098	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00009091 C00009094 C00009097 C00009098	0 / 0
O94806	Serine/threonine-protein kinase D3	Pkd	C00009091 C00009094 C00009097 C00009098	0 / 0
Q02156	Protein kinase C epsilon type	Eta	C00009091 C00009094 C00009097 C00009098	0 / 0
Q04759	Protein kinase C theta type	Delta	C00009091 C00009094 C00009097 C00009098	0 / 1
Q05513	Protein kinase C zeta type	Iota	C00009091 C00009094 C00009097 C00009098	0 / 0
Q05655	Protein kinase C delta type	Delta	C00009091 C00009094 C00009097 C00009098	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000999	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00000999	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000999	4 / 3
P83916	Chromobox protein homolog 1	Unclassified protein	C00000999	0 / 0
P59538	Taste receptor type 2 member 31	Taste receptor (taste family GPCR)	C00000999	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00000999	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00000999	1 / 4
Q9Y253	DNA polymerase eta	Enzyme	C00000999	1 / 1
O75496	Geminin	Unclassified protein	C00000999	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000999	2 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000999	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00000999	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000999	2 / 3
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00000999	1 / 4
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00000999	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00000999	1 / 1
P04062	Glucosylceramidase	Enzyme	C00000999	6 / 4
P33765	Adenosine receptor A3	Adenosine receptor	C00000999	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00000999	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions