Gentiana spp.

• Index
• Plant Species
• Metabolite list (12)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Gentiana spp.
Genus	Gentiana
Family	Gentianaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Gentiana
Linked NCBI taxonomy ID	21496
Linked level	genus

Family

Family in NCBI taxonomy	Gentianaceae
ID	21472

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (12)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00006205	Isoorientin 4'-O-glucoside					No. 1	No. 15
C00006393	Isosaponarin	CHEMBL1643081				No. 1	No. 15
C00014782	Delphinidin 3,3'-di-glucoside-5-(6-p-coumarylglucoside)					No. 7	No. 15
C00014781	Delphinidin 3,3'-di-glucoside-5-(6-caffeoylglucoside)					No. 7	No. 15
C00014820	Delphinidin 3-glucoside-5-(6-(E)-p-coumaroylglucoside)					No. 7	No. 15
C00001055	Isoorientin / Homoorientin / Lespecapitioside / Luteolin 6-C-beta-D-glucopyranoside / 2-(3,4-Dihydroxyphenyl)-6-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one	CHEMBL239559 CHEMBL1302308	C057912	23 / 14 / 17	0 / 1	No. 22	No. 15
C00001058	Isoscoparin / Isoorientin 3'-methyl ether					No. 22	No. 15
C00014819	Delphinidin 3-glucoside-5-(6-caffeoylglucoside)-3'-(6-(E)-p-coumaroylglucoside)					No. 62	No. 15
C00002648	Gentisic acid / 2,5-Dihydroxybenzoic acid	CHEMBL1461	C010925	15 / 6 / 8	2 / 1	No. 817	No. 81
C00001135	Gentianose	CHEMBL175500 CHEMBL603717				No. 1765
C00001977	Gentianine		C060402			No. 3439
C00001978	Gentiflavine					No. 8677

Human Protein / Gene in interactions

37 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9UNA4	DNA polymerase iota	Enzyme	C00001055 C00002648	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002648	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00002648	0 / 0
P06746	DNA polymerase beta	Enzyme	C00001055	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00001055	1 / 1
P43166	Carbonic anhydrase 7	Lyase	C00002648	0 / 0
P22894	Neutrophil collagenase	M10A	C00002648	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00002648	2 / 2
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001055	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00002648	1 / 2
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001055	1 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00002648	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00002648	1 / 2
P39748	Flap endonuclease 1	Enzyme	C00001055	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002648	0 / 0
P03956	Interstitial collagenase	M10A	C00002648	0 / 1
Q9Y253	DNA polymerase eta	Enzyme	C00001055	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00001055	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00001055	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00002648	0 / 1
P08253	72 kDa type IV collagenase	M10A	C00002648	1 / 3
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001055	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00002648	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00001055	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001055	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001055	4 / 3
P08254	Stromelysin-1	M10A	C00002648	1 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00001055	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001055	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00001055	1 / 1
O00255	Menin	Unclassified protein	C00001055	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001055	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001055	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001055	1 / 4
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001055	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00001055	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00001055	2 / 1

2 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
2539	G6PD, G6PD1	glucose-6-phosphate dehydrogenase (EC:1.1.1.49)	C00002648
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00002648

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions