| Organism name | Baccharis pilularis |
|---|---|
| Genus | Baccharis |
| Family | Asteraceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Baccharis |
|---|---|
| Linked NCBI taxonomy ID | 41487 |
| Linked level | genus |
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00001060
|
Kaempferide
|
CHEMBL40919
|
6 / 7 / 4 | No. 3 | No. 15 |
|
||
|
C00004638
|
Quercetin 3,7-dimethyl ether
/ 5,3',4'-Trihydroxy-3,7-dimethoxyflavone / 2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL164861
|
C065497
|
2 / 1 / 2 | No. 3 | No. 15 |
|
|
|
C00004567
|
Rhamnocitrin
/ 7-Methylkaempferol / 3,4',5-Trihydroxy-7-methoxyflavone / 3,5-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one |
CHEMBL442289
|
No. 3 | No. 15 |
|
|||
|
C00004634
|
Rhamnetin
/ 7-Methoxyquercetin / 3,5,3',4'-Tetrahydroxy-7-methoxyflavone / 2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1- benzopyran-4-one |
CHEMBL312163
|
C063423
|
20 / 27 / 27 | No. 3 | No. 15 |
|
|
|
C00004611
|
3-Methylherbacetin
/ 5,7,8,4'-Tetrahydroxy-3-methoxyflavone / 5,7,8-Trihydroxy-2-(4-hydroxyphenyl)-3-methoxy-4H-1-benzopyran-4-one |
No. 3 | No. 15 |
|
||||
|
C00004606
|
Mikanin
/ 3,5-Dihydroxy-4',6,7-trimethoxyflavone / 3,5-Dihydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL554063
|
No. 3 | No. 15 |
|
|||
|
C00004599
|
Eupalitin
/ Betuletol / 6,7-Dimethoxy-3,5,4'-trihydroxyflavone / 3,5-Dihydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one |
No. 3 | No. 15 |
|
||||
|
C00004573
|
3,7,4'-Tri-O-methylkaempferol
/ Kaempferol 3,7,4'-trimethyl ether / 5-Hydroxy-3,7,4'-trimethoxyflavone / 5-Hydroxy-3,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL77686
|
No. 35 | No. 15 |
|
|||
|
C00003848
|
Isoscutellarein
/ 8-Hydroxyapigenin / 4',5,7,8-Tetrahydroxyflavone / 5,7,8-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
No. 71 | No. 15 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9NPH5 | NADPH oxidase 4 | Enzyme | C00004638 | 0 / 0 |
| P00747 | Plasminogen | S1A | C00004638 | 1 / 2 |
| P45984 | Mitogen-activated protein kinase 9 | Jnk | C00004634 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00004634 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00004634 | 11 / 10 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00004634 | 3 / 1 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00001060 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00001060 | 1 / 0 |
| P04792 | Heat shock protein beta-1 | Unclassified protein | C00004634 | 2 / 1 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00004634 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00004634 | 0 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00001060 | 4 / 4 |
| P04745 | Alpha-amylase 1 | Enzyme | C00004634 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00004634 | 0 / 0 |
| P45983 | Mitogen-activated protein kinase 8 | Jnk | C00004634 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001060 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00004634 | 3 / 3 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00001060 | 2 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00001060 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00004634 | 0 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00004634 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00004634 | 4 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00004634 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00004634 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00004634 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00004634 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00004634 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00004634 | 1 / 2 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #606595 | Charcot-marie-tooth disease, axonal, type 2f; cmt2f |
P04792
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #608634 | Neuronopathy, distal hereditary motor, type iib; hmn2b |
P04792
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #217090 | Plasminogen deficiency, type i |
P00747
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00223 | Inherited thrombophilia |
P00747
(related)
|
| H01206 | Plasminogen deficiency |
P00747
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00856 | Distal hereditary motor neuropathies (dHMN) |
P04792
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|