| Organism name | Desmodium elegans |
|---|---|
| Genus | Desmodium |
| Family | Fabaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Desmodium elegans |
|---|---|
| Linked NCBI taxonomy ID | 149687 |
| Linked level | species |
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00001434
|
Tryptamine
/ beta-(3-Indolyl)ethylamine |
CHEMBL6640
|
C030820
|
20 / 5 / 7 | 6 / 2 | No. 710 | No. 4 |
|
|
C00001417
|
Cactine
/ Anhalin / Anhaline / Hordenine |
CHEMBL505789
|
C007964
|
1 / 0 / 0 | No. 936 | No. 6 |
|
|
|
C00001435
|
Tyramine
|
CHEMBL11608
|
D014439
|
23 / 11 / 6 | 6 / 9 | No. 936 | No. 6 |
|
|
C00001331
|
L-Abrine
|
CHEMBL552941
CHEMBL2360657 |
2 / 0 / 0 | No. 1432 | No. 4 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001434 C00001435 | 1 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001331 C00001435 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001434 C00001435 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001434 C00001435 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001434 C00001435 | 1 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001434 C00001435 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00001434 C00001435 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001434 C00001435 | 0 / 1 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001417 C00001435 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00001435 | 2 / 0 |
| P05164 | Myeloperoxidase | Enzyme | C00001434 | 1 / 2 |
| P43235 | Cathepsin K | C1A | C00001434 | 1 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001435 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00001434 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001434 | 1 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00001435 | 0 / 0 |
| P46098 | 5-hydroxytryptamine receptor 3A | NS | C00001435 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001435 | 0 / 0 |
| P28222 | 5-hydroxytryptamine receptor 1B | Serotonin receptor | C00001434 | 0 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00001434 | 0 / 0 |
| P56817 | Beta-secretase 1 | A1A | C00001435 | 0 / 0 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00001435 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001434 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00001434 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00001434 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00001434 | 0 / 0 |
| O15245 | Solute carrier family 22 member 1 | Drug uniporter | C00001435 | 0 / 0 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00001435 | 0 / 0 |
| Q96RJ0 | Trace amine-associated receptor 1 | Trace amine receptor | C00001435 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001434 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001434 | 0 / 0 |
| P28221 | 5-hydroxytryptamine receptor 1D | Serotonin receptor | C00001434 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001435 | 2 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001435 | 0 / 0 |
| O75751 | Solute carrier family 22 member 3 | Unclassified protein | C00001435 | 0 / 0 |
| Q05BR4 | SLC16A10 protein | Unclassified protein | C00001331 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00001435 | 4 / 2 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 6532 | SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT | solute carrier family 6 (neurotransmitter transporter), member 4 |
C00001434
C00001435
|
| 134864 | TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1 | trace amine associated receptor 1 |
C00001434
C00001435
|
| 6530 | SLC6A2, NAT1, NET, NET1, SLC6A5 | solute carrier family 6 (neurotransmitter transporter), member 2 |
C00001434
C00001435
|
| 6531 | SLC6A3, DAT, DAT1, PKDYS | solute carrier family 6 (neurotransmitter transporter), member 3 |
C00001434
C00001435
|
| 1548 | CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB | cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) |
C00001434
|
| 3356 | HTR2A, 5-HT2A, HTR2 | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
C00001434
|
| 4128 | MAOA, MAO-A | monoamine oxidase A (EC:1.4.3.4) |
C00001435
|
| 6818 | SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) |
C00001435
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P14416
|
| #300615 | Brunner syndrome |
P21397
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #254600 | Myeloperoxidase deficiency; mpod |
P05164
|
| #159900 | Myoclonic dystonia |
P14416
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #265800 | Pycnodysostosis |
P43235
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| KEGG | name | UniProt |
|---|---|---|
| H00101 | Other phagocyte defects |
P05164
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P05164
(marker)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00273 | Pycnodysostosis |
P43235
(related)
|
| H00425 | Lysosomal cysteine protease deficiencies |
P43235
(related)
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D012640 | Seizures |
C00001434
|
| D014202 | Tremor |
C00001434
|
| D009202 | Cardiomyopathies |
C00001435
|
| D002543 | Cerebral Hemorrhage |
C00001435
|
| D002637 | Chest Pain |
C00001435
|
| D006973 | Hypertension |
C00001435
|
| D007022 | Hypotension |
C00001435
|
| D008881 | Migraine Disorders |
C00001435
|
| D015878 | Mydriasis |
C00001435
|
| D011041 | Poisoning |
C00001435
|
| D013610 | Tachycardia |
C00001435
|