Species

KNApSAcK Entry

Organism name Cyperus papyrus
Genus Cyperus
Family Cyperaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cyperus papyrus
Linked NCBI taxonomy ID 76434
Linked level species

Family

Family in NCBI taxonomy Cyperaceae
ID 4609

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002493 External link 512 Pimpinellin
CHEMBL1491809
C039409
3 / 0 / 1 No. 606 No. 25
C00001425 External link 512 Octopamine
CHEMBL53929
CHEMBL1160703
D009655
16 / 8 / 6 7 / 0 No. 4586

Human Protein / Gene in interactions

18 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001425 C00002493 0 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001425 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00001425 2 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00001425 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00001425 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001425 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00002493 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00001425 0 / 0
P46098 5-hydroxytryptamine receptor 3A NS C00001425 0 / 0
Q99700 Ataxin-2 Unclassified protein C00001425 1 / 1
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00001425 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00002493 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001425 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001425 1 / 0
Q99549 M-phase phosphoprotein 8 Unclassified protein C00001425 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001425 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001425 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001425 0 / 0

7 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
153 ADRB1, ADRB1R, B1AR, BETA1AR, RHR adrenoceptor beta 1 C00001425
154 ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR adrenoceptor beta 2, surface C00001425
155 ADRB3, BETA3AR adrenoceptor beta 3 C00001425
6530 SLC6A2, NAT1, NET, NET1, SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 2 C00001425
6531 SLC6A3, DAT, DAT1, PKDYS solute carrier family 6 (neurotransmitter transporter), member 3 C00001425
6532 SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT solute carrier family 6 (neurotransmitter transporter), member 4 C00001425
134864 TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1 trace amine associated receptor 1 C00001425

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (6)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)