PCIDB

Kopsia griffithii

Species

KNApSAcK Entry

Organism name Kopsia griffithii
Genus Kopsia
Family Apocynaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Kopsia
Linked NCBI taxonomy ID 21101
Linked level genus

Family

Family in NCBI taxonomy Apocynaceae
ID 4056

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (16)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00024593 External link 512 Pleiocarpine
CHEMBL328281
No. 230
C00028696 External link 512 Kopsinine D
/ Kopsilongine
/ (-)-Kopsilongine
/ N-Methoxycarbonyl-12-methoxykopsinaline
/ (-)-N-(Methoxycarbonyl)-12-methoxykopsinaline
CHEMBL96596
No. 230
C00024460 External link 512 Kopsamine
/ (-)-Kopsinine F
/ (-)-N-Methoxycarbonyl-11,12-methylenedioxy-kopsinaline
CHEMBL327561
C061457
No. 230
C00038149 External link 512 12-Methoxypleiocarpine
/ (-)-12-Methoxypleiocarpine
CHEMBL314743
No. 230
C00025214 External link 512 Tetrahydroalstonine
CHEMBL122404
CHEMBL123325
CHEMBL498734
CHEMBL486933
CHEMBL1604074
CHEMBL2079609
32 / 28 / 31 No. 246 No. 4
C00027628 External link 512 (+)-Vincamone
/ d-Eburnamonine
/ (+)-Eburnamonine
/ (+)-cis-Vincamone
/ (+)-cis-Eburnamonine
CHEMBL1318553
CHEMBL1553441
CHEMBL1733074
CHEMBL1892145
C016422
14 / 20 / 16 2 / 0 No. 502 No. 4
C00024454 External link 512 Kopsinine
/ (-)-Kopsinine
CHEMBL93355
CHEMBL253984
C061491
No. 571
C00027675 External link 512 12-Methoxy-10-demethoxy-kopsidasinine
/ (-)-12-Methoxy-10-demethoxy-kopsidasinine
No. 880
C00027696 External link 512 Rhazinalinol
/ 16-Epideacetylakuammiline
/ 16-epi-Deacetylakuammiline
No. 1217
C00001736 External link 512 Harman
/ Harmane
/ Indoter
/ Locuturin
/ Zygofabagine
CHEMBL12014
C005010
109 / 46 / 33 2 / 2 No. 1889 No. 4
C00026538 External link 512 Harmicine
CHEMBL1831028
3 / 2 / 1 No. 2361 No. 4
C00026679 External link 512 Harmicine
/ (+)-Harmicine
CHEMBL1831028
3 / 2 / 1 No. 2361 No. 4
C00024567 External link 512 Leuconolam
/ (-)-Leuconolam
CHEMBL73223
C062173
No. 3903
C00040867 External link 512 Akuammiline N(4)-oxide
No. 4416
C00040772 External link 512 16-epi-Deacetylakuammiline N(4)-oxide
No. 4416
C00024568 External link 512 Leuconoxine
/ Diazaspiroleuconolam
No. 6033

Human Protein / Gene in interactions

140 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001736 C00025214 C00027628 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001736 C00025214 C00027628 0 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001736 C00025214 C00027628 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001736 C00025214 C00027628 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001736 C00025214 C00027628 0 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001736 C00025214 3 / 3
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001736 C00025214 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00025214 C00027628 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00001736 C00025214 0 / 0
O00255 Menin Unclassified protein C00001736 C00025214 2 / 5
P36544 Neuronal acetylcholine receptor subunit alpha-7 CHRN alpha C00026538 C00026679 0 / 0
P43681 Neuronal acetylcholine receptor subunit alpha-4 CHRN alpha C00026538 C00026679 1 / 1
P17787 Neuronal acetylcholine receptor subunit beta-2 CHRN beta C00026538 C00026679 1 / 1
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001736 C00025214 1 / 2
P16473 Thyrotropin receptor Glycohormone receptor C00001736 C00027628 3 / 2
P02545 Prelamin-A/C Unclassified protein C00025214 C00027628 11 / 10
P53778 Mitogen-activated protein kinase 12 p38 C00001736 0 / 0
Q8IWQ3 Serine/threonine-protein kinase BRSK2 CAMK serine/threonine protein kinase BRSK subfamily C00001736 0 / 0
P27448 MAP/microtubule affinity-regulating kinase 3 CAMK serine/threonine protein kinase MARK subfamily C00001736 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00025214 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00001736 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00025214 0 / 0
Q05513 Protein kinase C zeta type Iota C00001736 0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00001736 0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00001736 0 / 0
P17252 Protein kinase C alpha type Alpha C00001736 0 / 0
P23443 Ribosomal protein S6 kinase beta-1 p70 C00001736 0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00001736 0 / 0
Q9UQB9 Aurora kinase C Aur C00001736 1 / 1
Q9HBH9 MAP kinase-interacting serine/threonine-protein kinase 2 CAMK serine/threonine protein kinase MNK subfamily C00001736 0 / 0
Q9NQU5 Serine/threonine-protein kinase PAK 6 STE serine/threonine protein kinase PAKB subfamily C00001736 0 / 0
Q16644 MAP kinase-activated protein kinase 3 CAMK serine/threonine protein kinase MAPKAPK C00001736 0 / 0
Q9H422 Homeodomain-interacting protein kinase 3 CMGC dual-specificity kinase HIPK C00001736 0 / 0
Q14680 Maternal embryonic leucine zipper kinase Melk C00001736 0 / 0
P29466 Caspase-1 C14 C00025214 0 / 0
P45984 Mitogen-activated protein kinase 9 Jnk C00001736 0 / 0
P54132 Bloom syndrome protein Enzyme C00001736 1 / 2
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00025214 1 / 0
Q15746 Myosin light chain kinase, smooth muscle Mlck C00001736 1 / 1
Q13188 Serine/threonine-protein kinase 3 STE serine/threonine protein kinase MST subfamily C00001736 0 / 0
P31751 RAC-beta serine/threonine-protein kinase Akt C00001736 2 / 2
O75582 Ribosomal protein S6 kinase alpha-5 CAMK serine/threonine protein kinase MSKB subfamily C00001736 0 / 0
O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta Other serine/threonine protein kinase C00001736 0 / 0
Q16513 Serine/threonine-protein kinase N2 Pkn C00001736 0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd C00001736 0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme C00001736 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001736 0 / 0
P68871 Hemoglobin subunit beta Secreted protein C00025214 4 / 4
P17405 Sphingomyelin phosphodiesterase Enzyme C00025214 2 / 2
Q8N5S9 Calcium/calmodulin-dependent protein kinase kinase 1 META serine/threonine protein kinase subfamily C00001736 0 / 0
Q9P286 Serine/threonine-protein kinase PAK 7 STE serine/threonine protein kinase PAKB subfamily C00001736 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00025214 0 / 0
Q96SB4 SRSF protein kinase 1 Srpk C00001736 0 / 0
Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 CMGC dual-specificity kinase DYRK2 C00001736 0 / 0
O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 CMGC dual-specificity kinase DYRK2 C00001736 0 / 0
O96013 Serine/threonine-protein kinase PAK 4 STE serine/threonine protein kinase PAKB subfamily C00001736 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00025214 0 / 0
P42858 Huntingtin Unclassified protein C00025214 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00027628 2 / 0
O75496 Geminin Unclassified protein C00027628 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00025214 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00001736 0 / 0
Q15418 Ribosomal protein S6 kinase alpha-1 Rskb C00001736 0 / 0
O15264 Mitogen-activated protein kinase 13 p38 C00001736 0 / 0
P53779 Mitogen-activated protein kinase 10 Jnk C00001736 0 / 1
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00027628 0 / 0
P51955 Serine/threonine-protein kinase Nek2 Nek C00001736 0 / 0
Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 META serine/threonine protein kinase subfamily C00001736 0 / 0
Q9BUB5 MAP kinase-interacting serine/threonine-protein kinase 1 CAMK serine/threonine protein kinase MNK subfamily C00001736 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00027628 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00025214 0 / 0
Q99816 Tumor susceptibility gene 101 protein Unclassified protein C00025214 0 / 0
P48730 Casein kinase I isoform delta Ck1 C00001736 1 / 0
P41240 Tyrosine-protein kinase CSK Csk C00001736 0 / 0
Q96GD4 Aurora kinase B Aur C00001736 0 / 0
P49137 MAP kinase-activated protein kinase 2 CAMK serine/threonine protein kinase MAPKAPK C00001736 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00001736 0 / 0
P45983 Mitogen-activated protein kinase 8 Jnk C00001736 0 / 0
O15530 3-phosphoinositide-dependent protein kinase 1 Pdk1 C00001736 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00001736 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00001736 2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001736 0 / 0
P22303 Acetylcholinesterase Hydrolase C00001736 1 / 0
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily C00001736 0 / 0
Q8IW41 MAP kinase-activated protein kinase 5 CAMK serine/threonine protein kinase MAPKAPK C00001736 0 / 0
O75116 Rho-associated protein kinase 2 Rock C00001736 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00001736 0 / 0
P55210 Caspase-7 C14 C00025214 0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt C00001736 4 / 1
O00141 Serine/threonine-protein kinase Sgk1 AGC serine/threonine protein kinase SGK subfamily C00001736 0 / 0
P51812 Ribosomal protein S6 kinase alpha-3 Rskb C00001736 2 / 2
Q15759 Mitogen-activated protein kinase 11 p38 C00001736 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00001736 2 / 0
Q9HC98 Serine/threonine-protein kinase Nek6 Nek C00001736 0 / 0
Q9H2X6 Homeodomain-interacting protein kinase 2 CMGC dual-specificity kinase HIPK C00001736 0 / 0
Q99700 Ataxin-2 Unclassified protein C00027628 1 / 1
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00001736 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00025214 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001736 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00001736 4 / 3
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00025214 0 / 0
O96017 Serine/threonine-protein kinase Chk2 Rad53 C00001736 4 / 1
Q14012 Calcium/calmodulin-dependent protein kinase type 1 Camk1 C00001736 0 / 0
P17612 cAMP-dependent protein kinase catalytic subunit alpha Pka C00001736 0 / 0
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 C00001736 1 / 0
O14757 Serine/threonine-protein kinase Chk1 Chk1 C00001736 0 / 0
O00418 Eukaryotic elongation factor 2 kinase Atypical serine/threonine protein kinase alpha subfamily C00001736 0 / 0
Q8TD08 Mitogen-activated protein kinase 15 Mapk C00001736 0 / 0
Q86V86 Serine/threonine-protein kinase pim-3 Pim C00001736 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00025214 0 / 0
Q14145 Kelch-like ECH-associated protein 1 Unclassified protein C00025214 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00025214 0 / 0
Q8TDX7 Serine/threonine-protein kinase Nek7 Nek C00001736 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00025214 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00027628 1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00025214 0 / 0
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00001736 0 / 0
Q02750 Dual specificity mitogen-activated protein kinase kinase 1 Ste7 C00001736 1 / 1
Q9UN88 Gamma-aminobutyric acid receptor subunit theta GABA-A theta C00001736 0 / 0
P28472 Gamma-aminobutyric acid receptor subunit beta-3 GABA-A beta C00001736 1 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha C00001736 1 / 1
P48169 Gamma-aminobutyric acid receptor subunit alpha-4 GABA-A alpha C00001736 0 / 0
O14764 Gamma-aminobutyric acid receptor subunit delta GABA-A delta C00001736 1 / 1
P31644 Gamma-aminobutyric acid receptor subunit alpha-5 GABA-A alpha C00001736 0 / 0
Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 GABA-A gamma C00001736 0 / 0
P78334 Gamma-aminobutyric acid receptor subunit epsilon GABA-A epsilon C00001736 0 / 0
Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 GABA-A gamma C00001736 0 / 0
P34903 Gamma-aminobutyric acid receptor subunit alpha-3 GABA-A alpha C00001736 0 / 0
O00591 Gamma-aminobutyric acid receptor subunit pi GABA-A pi C00001736 0 / 0
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta C00001736 0 / 0
P18507 Gamma-aminobutyric acid receptor subunit gamma-2 GABA-A gamma C00001736 4 / 2
P18505 Gamma-aminobutyric acid receptor subunit beta-1 GABA-A beta C00001736 0 / 0
Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 GABA-A alpha C00001736 0 / 0
P47869 Gamma-aminobutyric acid receptor subunit alpha-2 GABA-A alpha C00001736 1 / 0
P20248 Cyclin-A2 Other cytosolic protein C00001736 0 / 0
P78396 Cyclin-A1 Other cytosolic protein C00001736 0 / 0
P68400 Casein kinase II subunit alpha Ck2 C00001736 0 / 0
P19784 Casein kinase II subunit alpha' Ck2 C00001736 0 / 0
P67870 Casein kinase II subunit beta REG serine/threonine protein kinase family C00001736 0 / 0
Q92698 DNA repair and recombination protein RAD54-like Enzyme C00001736 0 / 0

4 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
196 AHR, bHLHe76 aryl hydrocarbon receptor C00001736
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001736
1129 CHRM2, HM2 cholinergic receptor, muscarinic 2 C00027628
1132 CHRM4, HM4, M4R cholinergic receptor, muscarinic 4 C00027628

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (71)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#615224 Advanced sleep phase syndrome, familial, 2; fasps2 P48730
#103780 Alcohol dependence P47869
#613780 Aortic aneurysm, familial thoracic 7; aat7 Q15746
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#613985 Beta-thalassemia P68871
#603902 Beta-thalassemia, dominant inclusion body type P68871
#210900 Bloom syndrome; blm P54132
#114480 Breast cancer O96017
P31749
#615279 Cardiofaciocutaneous syndrome 3; cfc3 Q02750
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#303600 Coffin-lowry syndrome; cls P51812
#114500 Colorectal cancer; crc P31749
P84022
#615109 Cowden syndrome 6; cws6 P31749
#125853 Diabetes mellitus, noninsulin-dependent; niddm P31751
#119900 Digital clubbing, isolated congenital P15428
#607208 Dravet syndrome P18507
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#607681 Epilepsy, childhood absence, susceptibility to, 2; eca2 P18507
#612269 Epilepsy, childhood absence, susceptibility to, 5; eca5 P28472
#613060 Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 O14764
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#600513 Epilepsy, nocturnal frontal lobe, 1; enfl1 P43681
#605375 Epilepsy, nocturnal frontal lobe, 3; enfl3 P17787
#600274 Frontotemporal dementia; ftd P10636
#604233 Generalized epilepsy with febrile seizures plus, type 1; gefsp1 P18507
#611277 Generalized epilepsy with febrile seizures plus, type 3; gefsp3 P18507
#137800 Glioma susceptibility 1; glm1 O75874
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#140700 Heinz body anemias P68871
#143100 Huntington disease; hd P42858
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#240900 Hypoinsulinemic hypoglycemia with hemihypertrophy; hihghh P31751
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#609265 Li-fraumeni syndrome 2; lfs2 O96017
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300844 Mental retardation, x-linked 19; mrx19 P51812
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#259500 Osteogenic sarcoma O96017
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#176807 Prostate cancer O96017
#176920 Proteus syndrome P31749
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#603903 Sickle cell anemia P68871
#243060 Spermatogenic failure 5; spgf5 Q9UQB9
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#112100 Yt blood group antigen P22303

KEGG DISEASE (51)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00783 Febrile seizures O14764 (related)
P18507 (related)
H00881 Li-Fraumeni syndrome O96017 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P31751 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
P18507 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00807 Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) P17787 (related)
P43681 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H00027 Ovarian cancer P31751 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00480 Non-syndromic X-linked mental retardation P51812 (related)
Q99714 (related)
H00574 Coffin-Lowry syndrome (CLS) P51812 (related)
H00606 Early infantile epileptic encephalopathy P53779 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00228 Thalassemia P68871 (related)
H00229 Sickle cell anemia (SCA) P68871 (related)
H00020 Colorectal cancer P68871 (marker)
H00022 Bladder cancer P68871 (marker)
H00523 Noonan syndrome and related disorders Q02750 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00801 Familial thoracic aortic aneurysm and dissection (TAAD) Q15746 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H01282 Spermatogenic failure Q9UQB9 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D012640 Seizures C00001736
D014202 Tremor C00001736