PCIDB

KNApSAcK Metabolite C00001736

Metabolite

KNApSAcK Entry

id C00001736
Name Harman / Harmane / Indoter / Locuturin / Zygofabagine
CAS RN 486-84-0
Standard InChI InChI=1S/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H3
Standard InChI (Main Layer) InChI=1S/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H3

Cluster

Phytochemical cluster No. 4
KCF-S cluster No. 1889

Link

ChEMBL

By standard InChI CHEMBL12014
By standard InChI Main Layer CHEMBL12014

KEGG

By LinkDB C09209

CTD

By CAS RN C005010

Human Protein / Gene in interaction

109 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL12014 CHEMBL729206 (1) CHEMBL1614110 (3)
CHEMBL1741321 (2)
1 / 0
Q02750 Dual specificity mitogen-activated protein kinase kinase 1 Ste7 CHEMBL12014 CHEMBL1062820 (1)
1 / 1
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim CHEMBL12014 CHEMBL1061086 (1)
0 / 0
Q8TDX7 Serine/threonine-protein kinase Nek7 Nek CHEMBL12014 CHEMBL1060151 (1)
0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL12014 CHEMBL1794499 (1)
2 / 0
Q15759 Mitogen-activated protein kinase 11 p38 CHEMBL12014 CHEMBL1052111 (1)
0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 CHEMBL12014 CHEMBL1063767 (1)
0 / 0
O15530 3-phosphoinositide-dependent protein kinase 1 Pdk1 CHEMBL12014 CHEMBL1063811 (1)
0 / 0
P41240 Tyrosine-protein kinase CSK Csk CHEMBL12014 CHEMBL1061954 (1)
0 / 0
P45984 Mitogen-activated protein kinase 9 Jnk CHEMBL12014 CHEMBL1060122 (1)
0 / 0
P17252 Protein kinase C alpha type Alpha CHEMBL12014 CHEMBL1062776 (1)
0 / 0
P27361 Mitogen-activated protein kinase 3 Erk CHEMBL12014 CHEMBL1061959 (1)
0 / 0
O14757 Serine/threonine-protein kinase Chk1 Chk1 CHEMBL12014 CHEMBL1051374 (1)
0 / 0
Q8IWQ3 Serine/threonine-protein kinase BRSK2 CAMK serine/threonine protein kinase BRSK subfamily CHEMBL12014 CHEMBL1051367 (1)
0 / 0
P27448 MAP/microtubule affinity-regulating kinase 3 CAMK serine/threonine protein kinase MARK subfamily CHEMBL12014 CHEMBL1063734 (1)
0 / 0
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL12014 CHEMBL1614281 (1) CHEMBL1614361 (1)
3 / 2
Q05513 Protein kinase C zeta type Iota CHEMBL12014 CHEMBL1052114 (1)
0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim CHEMBL12014 CHEMBL1063736 (1)
0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 CHEMBL12014 CHEMBL666137 (1) CHEMBL1056886 (1)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL12014 CHEMBL1741325 (2)
0 / 1
P23443 Ribosomal protein S6 kinase beta-1 p70 CHEMBL12014 CHEMBL1052119 (1)
0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 CHEMBL12014 CHEMBL666138 (1)
0 / 0
Q9UQB9 Aurora kinase C Aur CHEMBL12014 CHEMBL1062797 (1)
1 / 1
Q9HBH9 MAP kinase-interacting serine/threonine-protein kinase 2 CAMK serine/threonine protein kinase MNK subfamily CHEMBL12014 CHEMBL1060126 (1)
0 / 0
Q9NQU5 Serine/threonine-protein kinase PAK 6 STE serine/threonine protein kinase PAKB subfamily CHEMBL12014 CHEMBL1063719 (1)
0 / 0
Q16644 MAP kinase-activated protein kinase 3 CAMK serine/threonine protein kinase MAPKAPK CHEMBL12014 CHEMBL1061148 (1)
0 / 0
Q9H422 Homeodomain-interacting protein kinase 3 CMGC dual-specificity kinase HIPK CHEMBL12014 CHEMBL1061964 (1)
0 / 0
Q14680 Maternal embryonic leucine zipper kinase Melk CHEMBL12014 CHEMBL1052104 (1)
0 / 0
P54132 Bloom syndrome protein Enzyme CHEMBL12014 CHEMBL1614522 (1)
1 / 2
Q15746 Myosin light chain kinase, smooth muscle Mlck CHEMBL12014 CHEMBL1062028 (1)
1 / 1
Q13188 Serine/threonine-protein kinase 3 STE serine/threonine protein kinase MST subfamily CHEMBL12014 CHEMBL1060209 (1)
0 / 0
P31751 RAC-beta serine/threonine-protein kinase Akt CHEMBL12014 CHEMBL1061917 (1)
2 / 2
O75582 Ribosomal protein S6 kinase alpha-5 CAMK serine/threonine protein kinase MSKB subfamily CHEMBL12014 CHEMBL1062767 (1)
0 / 0
O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta Other serine/threonine protein kinase CHEMBL12014 CHEMBL1062809 (1)
0 / 0
Q16513 Serine/threonine-protein kinase N2 Pkn CHEMBL12014 CHEMBL1060217 (1)
0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd CHEMBL12014 CHEMBL1062021 (1)
0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme CHEMBL12014 CHEMBL1613800 (1)
0 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL12014 CHEMBL1614458 (6)
0 / 0
Q8N5S9 Calcium/calmodulin-dependent protein kinase kinase 1 META serine/threonine protein kinase subfamily CHEMBL12014 CHEMBL1061198 (1)
0 / 0
Q9P286 Serine/threonine-protein kinase PAK 7 STE serine/threonine protein kinase PAKB subfamily CHEMBL12014 CHEMBL1061163 (1)
0 / 0
Q96SB4 SRSF protein kinase 1 Srpk CHEMBL12014 CHEMBL1060225 (1)
0 / 0
Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 CMGC dual-specificity kinase DYRK2 CHEMBL12014 CHEMBL1062802 (1)
0 / 0
O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 CMGC dual-specificity kinase DYRK2 CHEMBL12014 CHEMBL1061956 (1)
0 / 0
O96013 Serine/threonine-protein kinase PAK 4 STE serine/threonine protein kinase PAKB subfamily CHEMBL12014 CHEMBL1061162 (1)
0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk CHEMBL12014 CHEMBL1060118 (1)
0 / 0
Q15418 Ribosomal protein S6 kinase alpha-1 Rskb CHEMBL12014 CHEMBL1052116 (1)
0 / 0
O15264 Mitogen-activated protein kinase 13 p38 CHEMBL12014 CHEMBL1060132 (1)
0 / 0
P53779 Mitogen-activated protein kinase 10 Jnk CHEMBL12014 CHEMBL1060123 (1)
0 / 1
P51955 Serine/threonine-protein kinase Nek2 Nek CHEMBL12014 CHEMBL1062822 (1)
0 / 0
Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 META serine/threonine protein kinase subfamily CHEMBL12014 CHEMBL1052080 (1)
0 / 0
Q9BUB5 MAP kinase-interacting serine/threonine-protein kinase 1 CAMK serine/threonine protein kinase MNK subfamily CHEMBL12014 CHEMBL1063759 (1)
0 / 0
P48730 Casein kinase I isoform delta Ck1 CHEMBL12014 CHEMBL1062001 (1)
1 / 0
Q96GD4 Aurora kinase B Aur CHEMBL12014 CHEMBL1051365 (1)
0 / 0
P49137 MAP kinase-activated protein kinase 2 CAMK serine/threonine protein kinase MAPKAPK CHEMBL12014 CHEMBL1051342 (1)
0 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL12014 CHEMBL1052091 (1) CHEMBL1613808 (1)
0 / 0
P45983 Mitogen-activated protein kinase 8 Jnk CHEMBL12014 CHEMBL1061969 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL12014 CHEMBL1741322 (2)
0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL12014 CHEMBL1613910 (2) CHEMBL1614227 (2)
3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL12014 CHEMBL1614038 (5)
2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL12014 CHEMBL1738675 (1)
0 / 0
P22303 Acetylcholinesterase Hydrolase CHEMBL12014 CHEMBL2020014 (1) CHEMBL2020015 (1)
1 / 0
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily CHEMBL12014 CHEMBL1052115 (1)
0 / 0
Q8IW41 MAP kinase-activated protein kinase 5 CAMK serine/threonine protein kinase MAPKAPK CHEMBL12014 CHEMBL1061101 (1)
0 / 0
O75116 Rho-associated protein kinase 2 Rock CHEMBL12014 CHEMBL1063671 (1)
0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor CHEMBL12014 CHEMBL1614274 (1) CHEMBL1613823 (1)
0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt CHEMBL12014 CHEMBL1061172 (1)
4 / 1
O00141 Serine/threonine-protein kinase Sgk1 AGC serine/threonine protein kinase SGK subfamily CHEMBL12014 CHEMBL1063673 (1)
0 / 0
P51812 Ribosomal protein S6 kinase alpha-3 Rskb CHEMBL12014 CHEMBL1063683 (1)
2 / 2
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL12014 CHEMBL1741323 (2)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL12014 CHEMBL1614108 (1) CHEMBL1613886 (1)
CHEMBL1741324 (2)
0 / 1
Q9HC98 Serine/threonine-protein kinase Nek6 Nek CHEMBL12014 CHEMBL1060128 (1)
0 / 0
Q9H2X6 Homeodomain-interacting protein kinase 2 CMGC dual-specificity kinase HIPK CHEMBL12014 CHEMBL1062015 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL12014 CHEMBL1794483 (1)
0 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor CHEMBL12014 CHEMBL1614052 (1)
1 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL12014 CHEMBL1614283 (1) CHEMBL1614211 (4)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL12014 CHEMBL1614250 (1)
4 / 3
O96017 Serine/threonine-protein kinase Chk2 Rad53 CHEMBL12014 CHEMBL1062000 (1)
4 / 1
Q14012 Calcium/calmodulin-dependent protein kinase type 1 Camk1 CHEMBL12014 CHEMBL1051272 (1)
0 / 0
P17612 cAMP-dependent protein kinase catalytic subunit alpha Pka CHEMBL12014 CHEMBL1062854 (1)
0 / 0
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 CHEMBL12014 CHEMBL1062005 (1)
1 / 0
P53778 Mitogen-activated protein kinase 12 p38 CHEMBL12014 CHEMBL1062773 (1)
0 / 0
O00418 Eukaryotic elongation factor 2 kinase Atypical serine/threonine protein kinase alpha subfamily CHEMBL12014 CHEMBL1060113 (1)
0 / 0
Q8TD08 Mitogen-activated protein kinase 15 Mapk CHEMBL12014 CHEMBL1062012 (1)
0 / 0
Q86V86 Serine/threonine-protein kinase pim-3 Pim CHEMBL12014 CHEMBL1061912 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL12014 CHEMBL1613914 (5)
0 / 0
O00255 Menin Unclassified protein CHEMBL12014 CHEMBL1614531 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL12014 CHEMBL1614531 (1)
1 / 3
Q9UN88 Gamma-aminobutyric acid receptor subunit theta GABA-A theta CHEMBL12014 CHEMBL650075 (1)
0 / 0
P28472 Gamma-aminobutyric acid receptor subunit beta-3 GABA-A beta CHEMBL12014 CHEMBL650075 (1)
1 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha CHEMBL12014 CHEMBL650075 (1)
1 / 1
P48169 Gamma-aminobutyric acid receptor subunit alpha-4 GABA-A alpha CHEMBL12014 CHEMBL650075 (1)
0 / 0
O14764 Gamma-aminobutyric acid receptor subunit delta GABA-A delta CHEMBL12014 CHEMBL650075 (1)
1 / 1
P31644 Gamma-aminobutyric acid receptor subunit alpha-5 GABA-A alpha CHEMBL12014 CHEMBL650075 (1)
0 / 0
Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 GABA-A gamma CHEMBL12014 CHEMBL650075 (1)
0 / 0
P78334 Gamma-aminobutyric acid receptor subunit epsilon GABA-A epsilon CHEMBL12014 CHEMBL650075 (1)
0 / 0
Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 GABA-A gamma CHEMBL12014 CHEMBL650075 (1)
0 / 0
P34903 Gamma-aminobutyric acid receptor subunit alpha-3 GABA-A alpha CHEMBL12014 CHEMBL650075 (1)
0 / 0
O00591 Gamma-aminobutyric acid receptor subunit pi GABA-A pi CHEMBL12014 CHEMBL650075 (1)
0 / 0
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta CHEMBL12014 CHEMBL650075 (1)
0 / 0
P18507 Gamma-aminobutyric acid receptor subunit gamma-2 GABA-A gamma CHEMBL12014 CHEMBL650075 (1)
4 / 2
P18505 Gamma-aminobutyric acid receptor subunit beta-1 GABA-A beta CHEMBL12014 CHEMBL650075 (1)
0 / 0
Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 GABA-A alpha CHEMBL12014 CHEMBL650075 (1)
0 / 0
P47869 Gamma-aminobutyric acid receptor subunit alpha-2 GABA-A alpha CHEMBL12014 CHEMBL650075 (1)
1 / 0
P20248 Cyclin-A2 Other cytosolic protein CHEMBL12014 CHEMBL1056886 (1)
0 / 0
P78396 Cyclin-A1 Other cytosolic protein CHEMBL12014 CHEMBL1056886 (1)
0 / 0
P68400 Casein kinase II subunit alpha Ck2 CHEMBL12014 CHEMBL1061205 (1)
0 / 0
P19784 Casein kinase II subunit alpha' Ck2 CHEMBL12014 CHEMBL1061205 (1)
0 / 0
P67870 Casein kinase II subunit beta REG serine/threonine protein kinase family CHEMBL12014 CHEMBL1061205 (1)
0 / 0
Q92698 DNA repair and recombination protein RAD54-like Enzyme CHEMBL12014 CHEMBL2114865 (1)
0 / 0

CTD interaction (9)

compound gene gene name gene description interaction interaction type form reference
pmid
C005010 196 AHR
bHLHe76
aryl hydrocarbon receptor AHR mutant form inhibits the reaction [harman results in increased activity of CYP1A1 protein] decreases reaction
/ increases activity
mutant form 20732341
C005010 196 AHR
bHLHe76
aryl hydrocarbon receptor AHR mutant form inhibits the reaction [harman results in increased expression of CYP1A1 protein] decreases reaction
/ increases expression
mutant form 20732341
C005010 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) AHR mutant form inhibits the reaction [harman results in increased activity of CYP1A1 protein] decreases reaction
/ increases activity
protein 20732341
C005010 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) AHR mutant form inhibits the reaction [harman results in increased expression of CYP1A1 protein] decreases reaction
/ increases expression
protein 20732341
C005010 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Dactinomycin inhibits the reaction [harman results in increased expression of CYP1A1 mRNA] decreases reaction
/ increases expression
mRNA 20732341
C005010 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) harman results in increased activity of CYP1A1 protein increases activity
protein 20732341
C005010 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) harman results in increased expression of CYP1A1 mRNA increases expression
mRNA 20732341
C005010 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) harman results in increased expression of CYP1A1 protein increases expression
protein 20732341
C005010 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) resveratrol inhibits the reaction [harman results in increased activity of CYP1A1 protein] decreases reaction
/ increases activity
protein 20732341

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (46)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#615224 Advanced sleep phase syndrome, familial, 2; fasps2 P48730
#103780 Alcohol dependence P47869
#613780 Aortic aneurysm, familial thoracic 7; aat7 Q15746
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#210900 Bloom syndrome; blm P54132
#114480 Breast cancer O96017
P31749
#615279 Cardiofaciocutaneous syndrome 3; cfc3 Q02750
#303600 Coffin-lowry syndrome; cls P51812
#114500 Colorectal cancer; crc P31749
#615109 Cowden syndrome 6; cws6 P31749
#125853 Diabetes mellitus, noninsulin-dependent; niddm P31751
#119900 Digital clubbing, isolated congenital P15428
#607208 Dravet syndrome P18507
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#607681 Epilepsy, childhood absence, susceptibility to, 2; eca2 P18507
#612269 Epilepsy, childhood absence, susceptibility to, 5; eca5 P28472
#613060 Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 O14764
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#600274 Frontotemporal dementia; ftd P10636
#604233 Generalized epilepsy with febrile seizures plus, type 1; gefsp1 P18507
#611277 Generalized epilepsy with febrile seizures plus, type 3; gefsp3 P18507
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#240900 Hypoinsulinemic hypoglycemia with hemihypertrophy; hihghh P31751
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#609265 Li-fraumeni syndrome 2; lfs2 O96017
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300844 Mental retardation, x-linked 19; mrx19 P51812
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#259500 Osteogenic sarcoma O96017
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#176807 Prostate cancer O96017
#176920 Proteus syndrome P31749
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#243060 Spermatogenic failure 5; spgf5 Q9UQB9
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#112100 Yt blood group antigen P22303

KEGG DISEASE (33)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00783 Febrile seizures O14764 (related)
P18507 (related)
H00881 Li-Fraumeni syndrome O96017 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
P18507 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H00027 Ovarian cancer P31751 (related)
H00420 Familial partial lipodystrophy (FPL) P31751 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00480 Non-syndromic X-linked mental retardation P51812 (related)
Q99714 (related)
H00574 Coffin-Lowry syndrome (CLS) P51812 (related)
H00606 Early infantile epileptic encephalopathy P53779 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00523 Noonan syndrome and related disorders Q02750 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00801 Familial thoracic aortic aneurysm and dissection (TAAD) Q15746 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H01282 Spermatogenic failure Q9UQB9 (related)

Diseases related to CTD interactions

2 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D012640 C005010 Seizures marker/mechanism
6265841
D014202 C005010 Tremor marker/mechanism
21145352