Species

KNApSAcK Entry

Organism name Desmos longifolia
Genus Desmos
Family Annonaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Desmos
Linked NCBI taxonomy ID 984609
Linked level genus

Family

Family in NCBI taxonomy Annonaceae
ID 22140

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001928 External link 512 Xylopine
/ (-)-Xylopine
CHEMBL227689
CHEMBL452201
C062700
No. 20 No. 4
C00026108 External link 512 Aequaline
/ Discretamine
/ (-)-Discretamine
CHEMBL320397
CHEMBL2334883
7 / 3 / 0 No. 37 No. 4
C00025319 External link 512 Oxoxylopin
/ Oxoxylopine
/ Lanuginosine
CHEMBL389400
1 / 4 / 2 No. 74
C00001878 External link 512 Liriodenine
/ Oxoushinsunine
/ Spermatheridine
CHEMBL37736
C026980
5 / 3 / 1 No. 74

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P21728 D(1A) dopamine receptor Dopamine receptor C00026108 0 / 0
P30926 Neuronal acetylcholine receptor subunit beta-4 CHRN beta C00001878 0 / 0
P32297 Neuronal acetylcholine receptor subunit alpha-3 CHRN alpha C00001878 1 / 0
P17787 Neuronal acetylcholine receptor subunit beta-2 CHRN beta C00001878 1 / 1
P43681 Neuronal acetylcholine receptor subunit alpha-4 CHRN alpha C00001878 1 / 1
P14416 D(2) dopamine receptor Dopamine receptor C00026108 2 / 0
Q14761 Protein tyrosine phosphatase receptor type C-associated protein Enzyme C00001878 0 / 0
P35348 Alpha-1A adrenergic receptor Adrenergic receptor C00026108 0 / 0
P00734 Prothrombin S1A C00025319 4 / 2
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00026108 0 / 0
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00026108 1 / 0
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00026108 0 / 0
P35368 Alpha-1B adrenergic receptor Adrenergic receptor C00026108 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#103780 Alcohol dependence P14416
#600513 Epilepsy, nocturnal frontal lobe, 1; enfl1 P43681
#605375 Epilepsy, nocturnal frontal lobe, 3; enfl3 P17787
#159900 Myoclonic dystonia P14416
#614674 Periodic fever, menstrual cycle-dependent P08908
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#612052 Smoking as a quantitative trait locus 3; sqtl3 P32297
#601367 Stroke, ischemic P00734
#188050 Thrombophilia due to thrombin defect; thph1 P00734

KEGG DISEASE (3)

KEGG name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00807 Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) P17787 (related)
P43681 (related)