Senecio jacobaea
Species
KNApSAcK Entry
| Organism name | Senecio jacobaea |
|---|---|
| Genus | Senecio |
| Family | Asteraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Jacobaea vulgaris |
|---|---|
| Linked NCBI taxonomy ID | 98722 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (3)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002116
|
Senecionine
|
CHEMBL362153
CHEMBL488203 |
C009237
|
8 / 1 / 5 | 1 / 1 | No. 622 | No. 2 |
|
|
C00002119
|
Senkirkine
|
CHEMBL469650
CHEMBL470059 |
C009238
|
No. 838 | No. 2 |
|
||
|
C00002096
|
Jacobine
|
CHEMBL1969622
|
C013581
|
No. 1066 | No. 2 |
|
Human Protein / Gene in interactions
8 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P39748 | Flap endonuclease 1 | Enzyme | C00002116 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002116 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002116 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002116 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00002116 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002116 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002116 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002116 | 1 / 4 |
1 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 54657 | UGT1A4, HUG-BR2, UDPGT, UDPGT_1-4, UGT-1D, UGT1-04, UGT1.4, UGT1D | UDP glucuronosyltransferase 1 family, polypeptide A4 (EC:2.4.1.17) |
C00002116
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (1)
| OMIM | preferred title | UniProt |
|---|---|---|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
KEGG DISEASE (5)
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|