Species

KNApSAcK Entry

Organism name Neoraputia paraensis
Genus Neoraputia
Family Rutaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Rutaceae
Linked NCBI taxonomy ID 23513
Linked level family

Family

Family in NCBI taxonomy Rutaceae
ID 23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00004082 External link 512 5,6,7,3',4',5'-Hexamethoxyflavone
/ 5,6,7-Trimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL370963
1 / 1 / 0 No. 8 No. 15
C00003918 External link 512 5,7,3',4',5'-Pentamethoxyflavone
/ Tricetin 5,7,3',4',5'-pentamethyl ether
/ 5,7-Dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL2074901
1 / 1 / 0 No. 8 No. 15
C00003946 External link 512 5,4'-Dihidroxy-6,7,3',5'-tetramethoxyflavone
/ 5-Hydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one
CHEMBL1524286
16 / 10 / 6 No. 8 No. 15
C00013440 External link 512 5-Hydroxy-8-(4-hydroxy-3,5-dimethoxyphenyl)-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one
No. 24 No. 15
C00004006 External link 512 5,6,7,3'-Tetramethoxy-4',5'-methylenedioxyflavone
No. 27 No. 15
C00013402 External link 512 Ageconyflavone A
/ 3',4'-Methylenedioxy-5,6,7-trimethoxyflavone
/ 2-(1,3-Benzodioxol-5-yl)-5,6,7-trimethoxy-4H-1-benzopyran-4-one
No. 27 No. 15
C00002161 External link 512 Flindersiamine
/ 8-Methoxy-6,7-methylenedioxydictamnine
CHEMBL503519
C012321
No. 368 No. 7
C00026399 External link 512 8-O-Tigloyldiderroside
No. 799 No. 7
C00013441 External link 512 5-Hydroxy-8-(4-hydroxy-3,5-dimethoxyphenyl)-10-methoxy-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one
No. 1516

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08183 Multidrug resistance protein 1 drug C00003918 C00004082 1 / 0
Q9UNA4 DNA polymerase iota Enzyme C00003946 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00003946 0 / 0
Q99700 Ataxin-2 Unclassified protein C00003946 1 / 1
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00003946 1 / 0
P50281 Matrix metalloproteinase-14 M10A C00003946 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00003946 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00003946 0 / 0
P06746 DNA polymerase beta Enzyme C00003946 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00003946 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00003946 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00003946 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00003946 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00003946 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00003946 1 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00003946 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00003946 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc Q14191
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#612244 Inflammatory bowel disease 13; ibd13 P08183
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (6)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)