PCIDB

Veratrum stenophyllum

Species

KNApSAcK Entry

Organism name Veratrum stenophyllum
Genus Veratrum
Family Melanthiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Veratrum stenophyllum
Linked NCBI taxonomy ID 203102
Linked level species

Family

Family in NCBI taxonomy Melanthiaceae
ID 50362

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00002242 External link 512 alpha-Chaconine
C011860
No. 17 No. 11
C00029053 External link 512 Stenophylline B
C043148
No. 265 No. 11
C00029052 External link 512 Stenophylline A
No. 321 No. 11
C00029204 External link 512 Veratroylzygadenine
No. 321 No. 11
C00002253 External link 512 Jervine
CHEMBL186779
CHEMBL1402135
CHEMBL1717145
CHEMBL1742371
C010206
11 / 15 / 12 No. 587 No. 11
C00002272 External link 512 Zygadenine
No. 607 No. 11
C00027858 External link 512 Angeloylzygadenine
C077447
No. 607 No. 11

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase Enzyme C00002253 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002253 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002253 0 / 1
Q15465 Sonic hedgehog protein Unclassified protein C00002253 4 / 5
Q92830 Histone acetyltransferase KAT2A Enzyme C00002253 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00002253 1 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00002253 7 / 3
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002253 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002253 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002253 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00002253 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#302960 Chondrodysplasia punctata 2, x-linked dominant; cdpx2 Q15125
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#142945 Holoprosencephaly 3; hpe3 Q15465
#174800 Mccune-albright syndrome; mas P63092
#611638 Microphthalmia, isolated, with coloboma 5; mcopcb5 Q15465
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#174500 Polydactyly, preaxial ii; ppd2 Q15465
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#147250 Solitary median maxillary central incisor; smmci Q15465

KEGG DISEASE (12)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H01194 X-linked chondrodysplasia punctata Q15125 (related)
H00039 Basal cell carcinoma Q15465 (related)
H00267 Holoprosencephaly (HPE) Q15465 (related)
H00652 Solitary median maxillary central incisor syndrome Q15465 (related)
H01027 Anophthalmia and microphthalmia (A/M) Q15465 (related)
H01160 Schizencephaly Q15465 (related)