Species

KNApSAcK Entry

Organism name Veratrum dahuricum
Genus Veratrum
Family Melanthiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Veratrum dahuricum
Linked NCBI taxonomy ID 386441
Linked level species

Family

Family in NCBI taxonomy Melanthiaceae
ID 50362

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (11)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00029193 External link 512 Veramarine
No. 265 No. 11
C00029205 External link 512 Verazine
CHEMBL458682
CHEMBL457588
C052979
No. 265 No. 11
C00028946 External link 512 Rubijervine
CHEMBL1512978
CHEMBL1993702
5 / 2 / 3 No. 265 No. 11
C00028412 External link 512 Isorubijervine
No. 265 No. 11
C00029204 External link 512 Veratroylzygadenine
No. 321 No. 11
C00002253 External link 512 Jervine
CHEMBL186779
CHEMBL1402135
CHEMBL1717145
CHEMBL1742371
C010206
11 / 15 / 12 No. 587 No. 11
C00029209 External link 512 Verdine
No. 587 No. 11
C00029203 External link 512 Veratrosine
No. 1681 No. 11
C00002270 External link 512 Veratramine
CHEMBL464724
CHEMBL1398335
C009649
7 / 2 / 3 No. 1681 No. 11
C00029196 External link 512 Veramine
No. 1844 No. 11
C00028870 External link 512 Pseudojervine
/ Jervine 3-O-beta-D-glucopyranoside
/ 3beta-(D-glucopyranosyloxy)-jervine
No. 3567

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002253 C00002270 C00028946 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002253 C00002270 C00028946 0 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002253 C00002270 C00028946 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002253 C00002270 C00028946 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002253 C00002270 C00028946 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00002253 7 / 3
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00002253 1 / 0
P06276 Cholinesterase Hydrolase C00002270 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00002253 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00002270 0 / 0
Q15465 Sonic hedgehog protein Unclassified protein C00002253 4 / 5
Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase Enzyme C00002253 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00002253 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#302960 Chondrodysplasia punctata 2, x-linked dominant; cdpx2 Q15125
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#142945 Holoprosencephaly 3; hpe3 Q15465
#174800 Mccune-albright syndrome; mas P63092
#611638 Microphthalmia, isolated, with coloboma 5; mcopcb5 Q15465
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#174500 Polydactyly, preaxial ii; ppd2 Q15465
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#147250 Solitary median maxillary central incisor; smmci Q15465

KEGG DISEASE (12)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H01194 X-linked chondrodysplasia punctata Q15125 (related)
H00039 Basal cell carcinoma Q15465 (related)
H00267 Holoprosencephaly (HPE) Q15465 (related)
H00652 Solitary median maxillary central incisor syndrome Q15465 (related)
H01027 Anophthalmia and microphthalmia (A/M) Q15465 (related)
H01160 Schizencephaly Q15465 (related)