| Organism name | Lonchocarpus neuroscapha | 
|---|---|
| Genus | Lonchocarpus | 
| Family | Fabaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Lonchocarpus | 
|---|---|
| Linked NCBI taxonomy ID | 3925 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Fabaceae | 
|---|---|
| ID | 3803 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | rosids | 
|---|---|
| ID | 71275 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00007061   | Isobavachromene / 4-Hydroxylonchocarpin | CHEMBL362378 | 1 / 0 / 0 | No. 130 |   | |||
| C00007050   | Lonchocarpin | CHEMBL457644 | 1 / 2 / 0 | No. 130 |   | |||
| C00007067   | 4-Hydroxycordoin | CHEMBL460400 | 1 / 0 / 0 | No. 133 | No. 13 |   | ||
| C00007045   | Isocordoin | CHEMBL460618 | No. 133 | No. 13 |   | |||
| C00007052   | Derricin | CHEMBL455982 | No. 133 | No. 13 |   | |||
| C00007064   | 4-Hydroxyderricin | CHEMBL458094 | C068243 | 17 / 27 / 26 | No. 133 | No. 13 |   | |
| C00002381   | Corylifolinin / Isobavachalcone / 2',4,4'-Trihydroxy-3'-(3-methyl-2-butenyl)chalcone | CHEMBL253467 | C468754 | 8 / 22 / 21 | No. 133 | No. 13 |   | |
| C00007053   | Derricidin | CHEMBL450771 | 2 / 1 / 1 | No. 133 | No. 13 |   | ||
| C00008001   | Dihydrocordoin | No. 1291 |   | |||||
| C00007046   | 2',4'-Dihydroxy-3'-(1,1-dimethyl-2-propenyl)chalcone | No. 3383 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00007050 C00007064 | 2 / 0 | 
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00002381 | 0 / 0 | 
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00007053 | 0 / 0 | 
| P21802 | Fibroblast growth factor receptor 2 | TK tyrosine-protein kinase TLK subfamily | C00002381 | 9 / 3 | 
| P02545 | Prelamin-A/C | Unclassified protein | C00007064 | 11 / 10 | 
| P37840 | Alpha-synuclein | Unclassified protein | C00007064 | 4 / 2 | 
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00007053 | 1 / 1 | 
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00002381 | 1 / 8 | 
| P11926 | Ornithine decarboxylase | Lyase | C00007061 | 0 / 0 | 
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00007064 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00007064 | 0 / 0 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00007064 | 0 / 0 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00007064 | 0 / 0 | 
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00002381 | 2 / 2 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00007064 | 1 / 1 | 
| P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00002381 | 1 / 0 | 
| Q96RI1 | Bile acid receptor | NR1H4 | C00007067 | 0 / 0 | 
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00002381 | 2 / 3 | 
| P11362 | Fibroblast growth factor receptor 1 | Fgfr | C00002381 | 4 / 5 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00007064 | 0 / 0 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00007064 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00007064 | 4 / 3 | 
| P10721 | Mast/stem cell growth factor receptor Kit | Pdgfr | C00002381 | 4 / 3 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00007064 | 0 / 0 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00007064 | 1 / 0 | 
| O00255 | Menin | Unclassified protein | C00007064 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00007064 | 1 / 2 | 
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00007064 | 0 / 3 | 
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00007064 | 1 / 1 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 | Q13148 | 
| #207410 | Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 | P21802 | 
| #101200 | Apert syndrome | P21802 | 
| #613546 | Aromatase deficiency | P11511 | 
| #139300 | Aromatase excess syndrome; aexs | P11511 | 
| #123790 | Beare-stevenson cutis gyrata syndrome; bstvs | P21802 | 
| #614592 | Bent bone dysplasia syndrome; bbds | P21802 | 
| #300615 | Brunner syndrome | P21397 | 
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a | P02545 | 
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism | P02545 | 
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 | P02545 | 
| #114500 | Colorectal cancer; crc | P84022 | 
| #123500 | Crouzon syndrome | P21802 | 
| #127750 | Dementia, lewy body; dlb | P37840 | 
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 | P02545 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #606764 | Gastrointestinal stromal tumor; gist | P10721 | 
| #137800 | Glioma susceptibility 1; glm1 | O75874 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #610140 | Heart-hand syndrome, slovenian type | P02545 | 
| #602089 | Hemangioma, capillary infantile | P35968 | 
| #114550 | Hepatocellular carcinoma | P08581 | 
| #176670 | Hutchinson-gilford progeria syndrome; hgps | P02545 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #147950 | Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 | P11362 | 
| #123150 | Jackson-weiss syndrome; jws | P21802 | 
| #149730 | Lacrimoauriculodentodigital syndrome; ladd | P21802 | 
| #601626 | Leukemia, acute myeloid; aml | P10721 | 
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 | P02545 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #211980 | Lung cancer | P00533 | 
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada | P02545 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #613205 | Muscular dystrophy, congenital, lmna-related | P02545 | 
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b | P02545 | 
| #166250 | Osteoglophonic dysplasia; ogd | P11362 | 
| #168601 | Parkinson disease 1, autosomal dominant; park1 | P37840 | 
| #605543 | Parkinson disease 4, autosomal dominant; park4 | P37840 | 
| #168600 | Parkinson disease, late-onset; pd | P37840 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #101600 | Pfeiffer syndrome | P11362 P21802 | 
| #172700 | Pick disease of brain | P10636 | 
| #172800 | Piebald trait; pbt | P10721 | 
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 | P08581 | 
| #275210 | Restrictive dermopathy, lethal | P02545 | 
| #609579 | Scaphocephaly, maxillary retrusion, and mental retardation | P21802 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #273300 | Testicular germ cell tumor; tgct | P10721 | 
| #190440 | Trigonocephaly 1; trigno1 | P11362 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00016 | Oral cancer | P00533
                            (related) P00533 (marker) | 
| H00017 | Esophageal cancer | P00533
                            (related) | 
| H00018 | Gastric cancer | P00533
                            (related) P08581 (related) P21802 (related) | 
| H00022 | Bladder cancer | P00533
                            (related) | 
| H00028 | Choriocarcinoma | P00533
                            (related) | 
| H00030 | Cervical cancer | P00533
                            (related) | 
| H00042 | Glioma | P00533
                            (related) P00533 (marker) | 
| H00055 | Laryngeal cancer | P00533
                            (related) P00533 (marker) | 
| H00081 | Hashimoto's thyroiditis | P01215
                            (marker) | 
| H00082 | Graves' disease | P01215
                            (marker) | 
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) | P01215
                            (marker) | 
| H00264 | Charcot-Marie-Tooth disease (CMT) | P02545
                            (related) | 
| H00294 | Dilated cardiomyopathy (DCM) | P02545
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P02545
                            (related) | 
| H00563 | Emery-Dreifuss muscular dystrophy | P02545
                            (related) | 
| H00590 | Congenital muscular dystrophies (CMD/MDC) | P02545
                            (related) | 
| H00593 | Limb-girdle muscular dystrophy (LGMD) | P02545
                            (related) | 
| H00601 | Hutchinson-Gilford progeria syndrome | P02545
                            (related) | 
| H00663 | Restrictive dermopathy | P02545
                            (related) | 
| H00665 | Mandibuloacral dysplasia | P02545
                            (related) | 
| H01216 | Left ventricular noncompaction (LVNC) | P02545
                            (related) | 
| H00021 | Renal cell carcinoma | P08581
                            (related) | 
| H00046 | Cholangiocarcinoma | P08581
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) Q13148 (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00003 | Acute myeloid leukemia (AML) | P10721
                            (related) P10721 (marker) | 
| H00170 | Piebaldism | P10721
                            (related) | 
| H00023 | Testicular cancer | P10721
                            (marker) | 
| H00255 | Hypogonadotropic hypogonadism | P11362
                            (related) | 
| H00443 | Osteoglophonic dysplasia (OD) | P11362
                            (related) | 
| H00458 | Craniosynostosis | P11362
                            (related) P21802 (related) | 
| H00516 | Isolated orofacial clefts | P11362
                            (related) | 
| H01207 | Trigonocephaly | P11362
                            (related) | 
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) | P11511
                            (related) | 
| H00794 | Aromatase excess syndrome | P11511
                            (related) | 
| H00548 | Brunner syndrome | P21397
                            (related) | 
| H00642 | Lacrimo-auriculo-dento-digital syndrome (LADD) | P21802
                            (related) | 
| H00057 | Parkinson's disease (PD) | P37840
                            (related) | 
| H00066 | Lewy body dementia (LBD) | P37840
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) |