| Organism name | Lonchocarpus neuroscapha |
|---|---|
| Genus | Lonchocarpus |
| Family | Fabaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Lonchocarpus |
|---|---|
| Linked NCBI taxonomy ID | 3925 |
| Linked level | genus |
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00007061
|
Isobavachromene
/ 4-Hydroxylonchocarpin |
CHEMBL362378
|
1 / 0 / 0 | No. 130 |
|
|||
|
C00007050
|
Lonchocarpin
|
CHEMBL457644
|
1 / 2 / 0 | No. 130 |
|
|||
|
C00007067
|
4-Hydroxycordoin
|
CHEMBL460400
|
1 / 0 / 0 | No. 133 | No. 13 |
|
||
|
C00007045
|
Isocordoin
|
CHEMBL460618
|
No. 133 | No. 13 |
|
|||
|
C00007052
|
Derricin
|
CHEMBL455982
|
No. 133 | No. 13 |
|
|||
|
C00007064
|
4-Hydroxyderricin
|
CHEMBL458094
|
C068243
|
17 / 27 / 26 | No. 133 | No. 13 |
|
|
|
C00002381
|
Corylifolinin
/ Isobavachalcone / 2',4,4'-Trihydroxy-3'-(3-methyl-2-butenyl)chalcone |
CHEMBL253467
|
C468754
|
8 / 22 / 21 | No. 133 | No. 13 |
|
|
|
C00007053
|
Derricidin
|
CHEMBL450771
|
2 / 1 / 1 | No. 133 | No. 13 |
|
||
|
C00008001
|
Dihydrocordoin
|
No. 1291 |
|
|||||
|
C00007046
|
2',4'-Dihydroxy-3'-(1,1-dimethyl-2-propenyl)chalcone
|
No. 3383 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00007050 C00007064 | 2 / 0 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00002381 | 0 / 0 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00007053 | 0 / 0 |
| P21802 | Fibroblast growth factor receptor 2 | TK tyrosine-protein kinase TLK subfamily | C00002381 | 9 / 3 |
| P02545 | Prelamin-A/C | Unclassified protein | C00007064 | 11 / 10 |
| P37840 | Alpha-synuclein | Unclassified protein | C00007064 | 4 / 2 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00007053 | 1 / 1 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00002381 | 1 / 8 |
| P11926 | Ornithine decarboxylase | Lyase | C00007061 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00007064 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00007064 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00007064 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00007064 | 0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00002381 | 2 / 2 |
| Q99700 | Ataxin-2 | Unclassified protein | C00007064 | 1 / 1 |
| P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00002381 | 1 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00007067 | 0 / 0 |
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00002381 | 2 / 3 |
| P11362 | Fibroblast growth factor receptor 1 | Fgfr | C00002381 | 4 / 5 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00007064 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00007064 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00007064 | 4 / 3 |
| P10721 | Mast/stem cell growth factor receptor Kit | Pdgfr | C00002381 | 4 / 3 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00007064 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00007064 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00007064 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00007064 | 1 / 2 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00007064 | 0 / 3 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00007064 | 1 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #207410 | Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 |
P21802
|
| #101200 | Apert syndrome |
P21802
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #123790 | Beare-stevenson cutis gyrata syndrome; bstvs |
P21802
|
| #614592 | Bent bone dysplasia syndrome; bbds |
P21802
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #123500 | Crouzon syndrome |
P21802
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #606764 | Gastrointestinal stromal tumor; gist |
P10721
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #602089 | Hemangioma, capillary infantile |
P35968
|
| #114550 | Hepatocellular carcinoma |
P08581
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #147950 | Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 |
P11362
|
| #123150 | Jackson-weiss syndrome; jws |
P21802
|
| #149730 | Lacrimoauriculodentodigital syndrome; ladd |
P21802
|
| #601626 | Leukemia, acute myeloid; aml |
P10721
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
P00533
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #166250 | Osteoglophonic dysplasia; ogd |
P11362
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #101600 | Pfeiffer syndrome |
P11362
P21802 |
| #172700 | Pick disease of brain |
P10636
|
| #172800 | Piebald trait; pbt |
P10721
|
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #609579 | Scaphocephaly, maxillary retrusion, and mental retardation |
P21802
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #273300 | Testicular germ cell tumor; tgct |
P10721
|
| #190440 | Trigonocephaly 1; trigno1 |
P11362
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
|
| H00018 | Gastric cancer |
P00533
(related)
P08581 (related) P21802 (related) |
| H00022 | Bladder cancer |
P00533
(related)
|
| H00028 | Choriocarcinoma |
P00533
(related)
|
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00021 | Renal cell carcinoma |
P08581
(related)
|
| H00046 | Cholangiocarcinoma |
P08581
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P10721
(related)
P10721 (marker) |
| H00170 | Piebaldism |
P10721
(related)
|
| H00023 | Testicular cancer |
P10721
(marker)
|
| H00255 | Hypogonadotropic hypogonadism |
P11362
(related)
|
| H00443 | Osteoglophonic dysplasia (OD) |
P11362
(related)
|
| H00458 | Craniosynostosis |
P11362
(related)
P21802 (related) |
| H00516 | Isolated orofacial clefts |
P11362
(related)
|
| H01207 | Trigonocephaly |
P11362
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00642 | Lacrimo-auriculo-dento-digital syndrome (LADD) |
P21802
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|