| Organism name | Flourensia heterolepis | 
|---|---|
| Genus | Flourensia | 
| Family | Asteraceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Flourensia | 
|---|---|
| Linked NCBI taxonomy ID | 191157 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Asteraceae | 
|---|---|
| ID | 4210 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00008127   | 7-Methoxyflavanone | CHEMBL9687 | 5 / 6 / 7 | No. 25 | No. 14 |   | ||
| C00008126   | 7-Hydroxyflavanone | CHEMBL97542 CHEMBL402744 | C059353 | 9 / 18 / 45 | 1 / 0 | No. 25 | No. 14 |   | 
| C00008357   | 5,3',4'-Trihydroxy-7-methoxy-8-C-prenylflavanone | No. 28 | No. 14 |   | ||||
| C00021827   | Presilphiperfolanol | CHEMBL1966097 | No. 161 | No. 38 |   | |||
| C00012829   | [2R-(2alpha,4aalpha,5beta,8abeta)]-Decahydro-5-hydroxy-4a-methyl-a,8-bis(methylene)-2-naphthaleneacetic acid | No. 978 |   | |||||
| C00002399   | 6-Hydroxytremetone | No. 1831 |   | |||||
| C00012849   | Decahydro-alpha,4a-dimethyl-8-methylene-7-(2-methyl-1-oxopropoxy)-2-naphthaleneacetic acid | No. 2241 |   | |||||
| C00012851   | Decahydro-alpha,4a-dimethyl-8-methylene-7-(1-oxo-3-phenylpropoxy)-2-naphthaleneacetic acid | No. 2241 |   | |||||
| C00012847   | Decahydro-alpha,4a-dimethyl-8-methylene-7-[(3-methyl-1-oxo-2-butenyl)oxy]-2-naphthaleneacetic acid | No. 2241 |   | |||||
| C00012848   | Decahydro-alpha,4a-dimethyl-8-methylene-7-[(2-methyl-1-oxo-2-butenyl)oxy]-2-naphthaleneacetic acid | No. 2241 |   | |||||
| C00012850   | Decahydro-alpha,4a-dimethyl-8-methylene-7-(3-methyl-1-oxobutoxy)-2-naphthaleneacetic acid | No. 2241 |   | |||||
| C00012831   | 1-Oxo-4(15),11(13)-eudesmadien-12-oic acid / [2R-(2alpha,4aalpha,8abeta)]-Decahydro-4a-methyl-a,8-bis(methylene)-5-oxo-2-naphthaleneacetic acid | No. 3560 |   | |||||
| C00012832   | 1lapha-Hydroxy-4(15)-eudesmen-12-oic acid / Decahydro-5-hydroxy-alpha,4a-dimethyl-8-methylene-2-naphthaleneacetic acid | No. 7253 |   | |||||
| C00012830   | [2R-[2alpha,4aalpha,5beta(Z),8abeta]]-Decahydro-4a-methyl-alpha,8-bis(methylene)-5-[(2-methyl-1-oxo-2-butenyl)oxy]-2-naphthaleneacetic acid | No. 7659 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P10275 | Androgen receptor | NR3C4 | C00008126 C00008127 | 3 / 4 | 
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00008126 C00008127 | 0 / 0 | 
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00008126 C00008127 | 2 / 2 | 
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00008126 C00008127 | 1 / 1 | 
| P04150 | Glucocorticoid receptor | NR3C1 | C00008126 C00008127 | 0 / 1 | 
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00008126 | 4 / 2 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00008126 | 0 / 0 | 
| P05091 | Aldehyde dehydrogenase, mitochondrial | Oxidoreductase | C00008126 | 1 / 1 | 
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00008126 | 7 / 37 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 1588 | CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM | cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | C00008126 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc | P04637 | 
| #610251 | Alcohol sensitivity, acute | P05091 | 
| #300068 | Androgen insensitivity syndrome; ais | P10275 | 
| #312300 | Androgen insensitivity, partial; pais | P10275 | 
| #613546 | Aromatase deficiency | P11511 | 
| #139300 | Aromatase excess syndrome; aexs | P11511 | 
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 | P04637 | 
| #114480 | Breast cancer | P38398 | 
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 | P38398 | 
| #300615 | Brunner syndrome | P21397 | 
| #133239 | Esophageal cancer | P04637 | 
| #151623 | Li-fraumeni syndrome 1; lfs1 | P04637 | 
| #211980 | Lung cancer | P04637 | 
| #167000 | Ovarian cancer | P38398 | 
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 | P38398 | 
| #260500 | Papilloma of choroid plexus; cpp | P04637 | 
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 | P10275 | 
| #275355 | Squamous cell carcinoma, head and neck; hnscc | P04637 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) | P04150
                            (related) P11511 (related) | 
| H00004 | Chronic myeloid leukemia (CML) | P04637
                            (related) | 
| H00005 | Chronic lymphocytic leukemia (CLL) | P04637
                            (related) | 
| H00006 | Hairy-cell leukemia | P04637
                            (related) | 
| H00008 | Burkitt lymphoma | P04637
                            (related) | 
| H00009 | Adult T-cell leukemia | P04637
                            (related) | 
| H00010 | Multiple myeloma | P04637
                            (related) | 
| H00013 | Small cell lung cancer | P04637
                            (related) | 
| H00014 | Non-small cell lung cancer | P04637
                            (related) | 
| H00015 | Malignant pleural mesothelioma | P04637
                            (related) | 
| H00016 | Oral cancer | P04637
                            (related) P04637 (marker) | 
| H00017 | Esophageal cancer | P04637
                            (related) P04637 (marker) | 
| H00018 | Gastric cancer | P04637
                            (related) | 
| H00019 | Pancreatic cancer | P04637
                            (related) P04637 (marker) | 
| H00020 | Colorectal cancer | P04637
                            (related) P04637 (marker) | 
| H00022 | Bladder cancer | P04637
                            (related) | 
| H00025 | Penile cancer | P04637
                            (related) P04637 (marker) | 
| H00026 | Endometrial Cancer | P04637
                            (related) | 
| H00027 | Ovarian cancer | P04637
                            (related) P38398 (related) | 
| H00028 | Choriocarcinoma | P04637
                            (related) | 
| H00029 | Vulvar cancer | P04637
                            (related) | 
| H00031 | Breast cancer | P04637
                            (related) P38398 (related) | 
| H00032 | Thyroid cancer | P04637
                            (related) | 
| H00033 | Adrenal carcinoma | P04637
                            (related) | 
| H00036 | Osteosarcoma | P04637
                            (related) | 
| H00038 | Malignant melanoma | P04637
                            (related) | 
| H00039 | Basal cell carcinoma | P04637
                            (related) | 
| H00040 | Squamous cell carcinoma | P04637
                            (related) | 
| H00041 | Kaposi's sarcoma | P04637
                            (related) | 
| H00042 | Glioma | P04637
                            (related) P04637 (marker) | 
| H00044 | Cancer of the anal canal | P04637
                            (related) | 
| H00046 | Cholangiocarcinoma | P04637
                            (related) | 
| H00047 | Gallbladder cancer | P04637
                            (related) | 
| H00048 | Hepatocellular carcinoma | P04637
                            (related) | 
| H00055 | Laryngeal cancer | P04637
                            (related) P04637 (marker) | 
| H00881 | Li-Fraumeni syndrome | P04637
                            (related) | 
| H01007 | Choroid plexus papilloma | P04637
                            (related) | 
| H00021 | Renal cell carcinoma | P04637
                            (marker) | 
| H01071 | Acute alcohol sensitivity | P05091
                            (related) | 
| H00024 | Prostate cancer | P10275
                            (related) | 
| H00062 | Spinal and bulbar muscular atrophy (SBMA) | P10275
                            (related) | 
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) | P10275
                            (related) | 
| H00609 | 46,XY disorders of sex development (Other) | P10275
                            (related) | 
| H00794 | Aromatase excess syndrome | P11511
                            (related) | 
| H00548 | Brunner syndrome | P21397
                            (related) |