Species

KNApSAcK Entry

Organism name Flourensia heterolepis
Genus Flourensia
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Flourensia
Linked NCBI taxonomy ID 191157
Linked level genus

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (14)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00008127 External link 512 7-Methoxyflavanone
CHEMBL9687
5 / 6 / 7 No. 25 No. 14
C00008126 External link 512 7-Hydroxyflavanone
CHEMBL97542
CHEMBL402744
C059353
9 / 18 / 45 1 / 0 No. 25 No. 14
C00008357 External link 512 5,3',4'-Trihydroxy-7-methoxy-8-C-prenylflavanone
No. 28 No. 14
C00021827 External link 512 Presilphiperfolanol
CHEMBL1966097
No. 161 No. 38
C00012829 External link 512 [2R-(2alpha,4aalpha,5beta,8abeta)]-Decahydro-5-hydroxy-4a-methyl-a,8-bis(methylene)-2-naphthaleneacetic acid
No. 978
C00002399 External link 512 6-Hydroxytremetone
No. 1831
C00012849 External link 512 Decahydro-alpha,4a-dimethyl-8-methylene-7-(2-methyl-1-oxopropoxy)-2-naphthaleneacetic acid
No. 2241
C00012851 External link 512 Decahydro-alpha,4a-dimethyl-8-methylene-7-(1-oxo-3-phenylpropoxy)-2-naphthaleneacetic acid
No. 2241
C00012847 External link 512 Decahydro-alpha,4a-dimethyl-8-methylene-7-[(3-methyl-1-oxo-2-butenyl)oxy]-2-naphthaleneacetic acid
No. 2241
C00012848 External link 512 Decahydro-alpha,4a-dimethyl-8-methylene-7-[(2-methyl-1-oxo-2-butenyl)oxy]-2-naphthaleneacetic acid
No. 2241
C00012850 External link 512 Decahydro-alpha,4a-dimethyl-8-methylene-7-(3-methyl-1-oxobutoxy)-2-naphthaleneacetic acid
No. 2241
C00012831 External link 512 1-Oxo-4(15),11(13)-eudesmadien-12-oic acid
/ [2R-(2alpha,4aalpha,8abeta)]-Decahydro-4a-methyl-a,8-bis(methylene)-5-oxo-2-naphthaleneacetic acid
No. 3560
C00012832 External link 512 1lapha-Hydroxy-4(15)-eudesmen-12-oic acid
/ Decahydro-5-hydroxy-alpha,4a-dimethyl-8-methylene-2-naphthaleneacetic acid
No. 7253
C00012830 External link 512 [2R-[2alpha,4aalpha,5beta(Z),8abeta]]-Decahydro-4a-methyl-alpha,8-bis(methylene)-5-[(2-methyl-1-oxo-2-butenyl)oxy]-2-naphthaleneacetic acid
No. 7659

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10275 Androgen receptor NR3C4 C00008126 C00008127 3 / 4
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00008126 C00008127 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00008126 C00008127 2 / 2
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00008126 C00008127 1 / 1
P04150 Glucocorticoid receptor NR3C1 C00008126 C00008127 0 / 1
P38398 Breast cancer type 1 susceptibility protein Enzyme C00008126 4 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00008126 0 / 0
P05091 Aldehyde dehydrogenase, mitochondrial Oxidoreductase C00008126 1 / 1
P04637 Cellular tumor antigen p53 Transcription Factor C00008126 7 / 37

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00008126

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#610251 Alcohol sensitivity, acute P05091
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#133239 Esophageal cancer P04637
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#211980 Lung cancer P04637
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#275355 Squamous cell carcinoma, head and neck; hnscc P04637

KEGG DISEASE (45)

KEGG name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H01071 Acute alcohol sensitivity P05091 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00548 Brunner syndrome P21397 (related)