Species

KNApSAcK Entry

Organism name Cedrelopsis grevei Baill
Genus Cedrelopsis
Family Meliaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cedrelopsis
Linked NCBI taxonomy ID 864330
Linked level genus

Family

Family in NCBI taxonomy Rutaceae
ID 23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00037581 External link 512 O-Methylcedrelopsin
CHEMBL1338393
2 / 0 / 0 No. 466 No. 25
C00036085 External link 512 Cedrecoumarin B
/ Microfolicoumarin
No. 466 No. 25
C00036889 External link 512 Cedrelopsin
No. 466 No. 25
C00036084 External link 512 Cedrecoumarin A
CHEMBL491519
2 / 1 / 1 No. 750 No. 25
C00037561 External link 512 Norbraylin
No. 750 No. 25
C00002498 External link 512 Scoparone
/ 6,7-Dimethoxycoumarin
/ Aesculetin dimethyl ether
CHEMBL325864
C018145
4 / 2 / 2 6 / 0 No. 864 No. 25

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P05091 Aldehyde dehydrogenase, mitochondrial Oxidoreductase C00002498 1 / 1
Q92731 Estrogen receptor beta NR3A2 C00036084 0 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00037581 0 / 0
P56817 Beta-secretase 1 A1A C00002498 0 / 0
P03372 Estrogen receptor NR3A1 C00036084 1 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00037581 0 / 0
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00002498 0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00002498 1 / 1

6 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00002498
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00002498
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00002498
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00002498
5966 REL, C-Rel v-rel avian reticuloendotheliosis viral oncogene homolog C00002498
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00002498

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#610251 Alcohol sensitivity, acute P05091
#300615 Brunner syndrome P21397
#615363 Estrogen resistance; estrr P03372

KEGG DISEASE (3)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
Q92731 (marker)
H01071 Acute alcohol sensitivity P05091 (related)
H00548 Brunner syndrome P21397 (related)