Species

KNApSAcK Entry

Organism name Dalbergia sericea
Genus Dalbergia
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Dalbergia
Linked NCBI taxonomy ID 53862
Linked level genus

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (10)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005396 External link 512 Quercetin 3-galactosyl-(1->4)-galactoside
No. 1 No. 15
C00008671 External link 512 Aromadendrin 3-glucoside
No. 12 No. 14
C00003758 External link 512 Alnulin
/ Tiliadin
/ Skimmiol
/ Taraxerol
CHEMBL511822
CHEMBL470462
C005802
No. 13 No. 51
C00031826 External link 512 Glutinol
/ D:B-Friedoolean-5-en-3beta-ol
/ (+)-D:B-Friedoolean-5-en-3beta-ol
CHEMBL452242
No. 13 No. 51
C00003740 External link 512 Betulin
CHEMBL23236
CHEMBL140040
CHEMBL1610940
CHEMBL2000891
CHEMBL2069124
C002503
18 / 16 / 17 0 / 2 No. 23 No. 51
C00002565 External link 512 Pseudobaptigenin
CHEMBL486176
C060800
3 / 5 / 3 No. 27 No. 15
C00009406 External link 512 Fujikinetin
/ 7-Hydroxy-6-methoxy-3',4'-methylenedioxyisoflavone
CHEMBL485985
No. 27 No. 15
C00002547 External link 512 (-)-Medicarpin
/ 3-Hydroxy-9-methoxypterocarpan
CHEMBL238845
CHEMBL413297
C047353
3 / 1 / 1 No. 66 No. 15
C00002546 External link 512 Inermin
/ Maackiain
/ (-)-Maackiain
/ Demethylpterocarpin
/ 3-Hydroxy-8,9-methylenedioxypterocarpan
CHEMBL334918
CHEMBL239047
CHEMBL445279
3 / 2 / 3 No. 66 No. 15
C00009710 External link 512 Neovestitol
/ 2',4'-Dihydroxy-7-methoxyisoflavan
No. 73 No. 15

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002546 C00003740 0 / 1
P11388 DNA topoisomerase 2-alpha Isomerase C00003740 0 / 0
P13866 Sodium/glucose cotransporter 1 Glucose C00002546 1 / 1
P31639 Sodium/glucose cotransporter 2 Glucose C00002546 1 / 1
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00003740 0 / 3
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00002565 0 / 0
Q8TDU6 G-protein coupled bile acid receptor 1 Steroid-like ligand receptor C00003740 0 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00003740 0 / 0
P02545 Prelamin-A/C Unclassified protein C00003740 11 / 10
P10828 Thyroid hormone receptor beta NR1A2 C00003740 3 / 1
Q02156 Protein kinase C epsilon type Eta C00003740 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003740 0 / 1
P11387 DNA topoisomerase 1 Isomerase C00003740 0 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00003740 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00003740 0 / 0
O75496 Geminin Unclassified protein C00002547 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00003740 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00002565 5 / 3
Q96RI1 Bile acid receptor NR1H4 C00003740 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00003740 0 / 0
P05771 Protein kinase C beta type Alpha C00003740 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003740 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003740 1 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002547 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00002565 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002547 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (24)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
%606641 Body mass index; bmi P37231
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#137800 Glioma susceptibility 1; glm1 P37231
#606824 Glucose/galactose malabsorption; ggm P13866
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#601665 Obesity P37231
#233100 Renal glucosuria; glys1 P31639
#275210 Restrictive dermopathy, lethal P02545
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (22)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H01261 Congenital glucose-galactose malabsorption (GGM) P13866 (related)
H01126 Familial renal glucosuria (FRG) P31639 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003110 Colonic Neoplasms C00003740
D064420 Drug-Related Side Effects and Adverse Reactions C00003740