Species

KNApSAcK Entry

Organism name Glycyrrhiza spp.
Genus Glycyrrhiza
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Glycyrrhiza
Linked NCBI taxonomy ID 46347
Linked level genus

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (14)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006236 External link 512 Isoviolanthin
No. 1 No. 15
C00008193 External link 512 Liquiritin
CHEMBL511995
8 / 8 / 38 No. 12 No. 14
C00010077 External link 512 Gancaonin I
No. 15 No. 15
C00009877 External link 512 Glisoflavone
/ 7,3',4'-Trihydroxy-5-methoxy-5'-prenylisoflavone
CHEMBL1223641
C063349
1 / 0 / 0 No. 15 No. 15
C00002583 External link 512 (+)-Vestitol
/ (3S)-Vestitol
/ (3S)-3,4-Dihydro-3-(2-hydroxy-4-methoxyphenyl)-2H-1-benzopyran-7-ol
CHEMBL252913
CHEMBL479145
No. 73 No. 15
C00009964 External link 512 Glycyrrhisoflavanone
No. 127 No. 14
C00019338 External link 512 Gancaonin X
/ 2'-Hydroxy-4'-methoxy-6'',6''-dimethylpyrano[2'',3'':7,6]isoflavan
No. 135 No. 15
C00019323 External link 512 Gancaonol C
/ 7,4'-Dihydroxy-5-methoxy-6'',6''-dimethylpyrano[2'',3'':2',3']isoflavan
No. 135 No. 15
C00019339 External link 512 Gancaonin Y
/ 7-Hydroxy-4'-methoxy-6'',6''-dimethylpyrano[2'',3'':2',3']isoflavan
No. 135 No. 15
C00010062 External link 512 Gancaonin F
No. 377
C00019322 External link 512 Gancaonol B
/ 7-Hydroxy-9-methoxy-6',6'-dimethylpyrano[2',3':3,4]-coumestan
No. 377
C00010043 External link 512 Licoarylcoumarin
No. 436 No. 17
C00019360 External link 512 Gancaonin W
/ 7,2',4'-Trihydroxy-5-methoxy-3'-prenyl-3-phenylcoumarin
No. 436 No. 17
C00019321 External link 512 Gancaonol A
/ 7-Hydroxy-5,2'-dimethoxy-6'',6''-dimethyl-4'',5''-dihydropyrano[2'',3'':4',3']-3-phenylcoumarin
No. 582 No. 17

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00009877 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00008193 7 / 37
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00008193 0 / 0
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00008193 0 / 1
P07237 Protein disulfide-isomerase Enzyme C00008193 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00008193 1 / 0
O75496 Geminin Unclassified protein C00008193 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00008193 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00008193 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#133239 Esophageal cancer P04637
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#211980 Lung cancer P04637
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260500 Papilloma of choroid plexus; cpp P04637
#275355 Squamous cell carcinoma, head and neck; hnscc P04637

KEGG DISEASE (38)

KEGG name UniProt
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00079 Asthma P07550 (related)