Species

KNApSAcK Entry

Organism name Torreya nucifera var.radicans
Genus Torreya
Family Taxaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Torreya
Linked NCBI taxonomy ID 50188
Linked level genus

Family

Family in NCBI taxonomy Taxaceae
ID 25623

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Spermatophyta
ID 58024

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00037890 External link 512 Taxusabietane A
/ (+)-Taxusabietane A
No. 355
C00037882 External link 512 Taiwanin F
No. 355
C00003426 External link 512 Ferruginol
CHEMBL197308
No. 359 No. 40
C00002609 External link 512 Hinokiol
/ (+)-Hinokiol
CHEMBL16901
26 / 24 / 20 No. 761 No. 23

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00002609 1 / 1
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00002609 0 / 0
P06746 DNA polymerase beta Enzyme C00002609 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00002609 1 / 1
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00002609 0 / 0
P37840 Alpha-synuclein Unclassified protein C00002609 4 / 2
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00002609 0 / 0
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta C00002609 0 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha C00002609 1 / 1
P34972 Cannabinoid receptor 2 Cannabinoid receptor C00002609 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00002609 2 / 2
P39748 Flap endonuclease 1 Enzyme C00002609 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00002609 2 / 0
O75496 Geminin Unclassified protein C00002609 0 / 0
Q9Y2T6 G-protein coupled receptor 55 Lysophosphatidylinositol receptor C00002609 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00002609 0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00002609 0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00002609 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00002609 5 / 3
Q13133 Oxysterols receptor LXR-alpha NR1H3 C00002609 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00002609 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002609 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00002609 4 / 3
Q9GZV3 High affinity choline transporter 1 Choline Na-symporter C00002609 1 / 0
O00255 Menin Unclassified protein C00002609 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002609 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (24)

OMIM preferred title UniProt
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 P37231
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#158580 Neuronopathy, distal hereditary motor, type viia; hmn7a Q9GZV3
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#601665 Obesity P37231
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (20)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)