Ligularia dentata Hara

• Index
• Plant Species
• Metabolite list (12)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Ligularia dentata Hara
Genus	Ligularia
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Ligularia
Linked NCBI taxonomy ID	4239
Linked level	genus

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (12)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003749	Lupeol / Lupenol / (+)-Lupenol	CHEMBL289191 CHEMBL459702	C010480	3 / 0 / 0	2 / 6	No. 23	No. 51
C00031394	Stigmast 4-ene 3,6-dione / (-)-Stigmast 4-ene 3,6-dione		C017726			No. 53	No. 11
C00029821	Sitostenone / beta-Sitostenone / Stigmast-4-en-3-one / Stigmast-4-ene-3-one	CHEMBL66926				No. 53	No. 11
C00011163	Butyrospermol / (-)-Butyrospermol	CHEMBL1835433				No. 119	No. 51
C00026211	Ligularidine / O-Acetylcrotaverrine					No. 838	No. 2
C00026213	Ligularizine / 12-Epipetasitenine acetate / O-Acetyl-12-epifukinotoxin					No. 838	No. 2
C00026215	Neoligularidine					No. 838	No. 2
C00029337	Methyl (E)-ferulate / Methyl trans-ferulate / (E)-Methyl-4-hydroxy-3-methoxycinnamate	CHEMBL32969				No. 876
C00002683	Vanillin	CHEMBL13883		18 / 8 / 9		No. 1003
C00026212	Ligularinine / 12-Epiplatyphylline	CHEMBL1585045		4 / 0 / 0		No. 1044	No. 2
C00029305	(+)-Methyl abscisate					No. 1435	No. 38
C00030756	Methyl indole-3-carboxylate					No. 2665

Human Protein / Gene in interactions

25 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00002683	0 / 0
P78527	DNA-dependent protein kinase catalytic subunit	Atypical serine/threonine protein kinase PIKK subfamily	C00002683	0 / 0
P06746	DNA polymerase beta	Enzyme	C00026212	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00026212	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00003749	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002683	0 / 0
P51649	Succinate-semialdehyde dehydrogenase, mitochondrial	Oxidoreductase	C00002683	1 / 1
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00002683	0 / 0
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00002683	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00003749	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003749	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002683	0 / 0
O75496	Geminin	Unclassified protein	C00026212	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00002683	0 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00002683	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00026212	0 / 0
P80404	4-aminobutyrate aminotransferase, mitochondrial	Transferase	C00002683	1 / 1
Q96RI1	Bile acid receptor	NR1H4	C00002683	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002683	2 / 2
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00002683	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00002683	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002683	0 / 0
P10275	Androgen receptor	NR3C4	C00002683	3 / 4
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002683	1 / 1
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002683	0 / 0

2 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00003749
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00003749

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions