Piper sanctum
Species
KNApSAcK Entry
| Organism name | Piper sanctum |
|---|---|
| Genus | Piper |
| Family | Piperaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Piper sanctum |
|---|---|
| Linked NCBI taxonomy ID | 511552 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Piperaceae |
|---|---|
| ID | 16739 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Magnoliophyta |
|---|---|
| ID | 3398 |
Metabolite list (6)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00025791
|
Cepharanone B
/ Aristolactam BII / Aristololactam B II |
CHEMBL226772
|
C064674
|
No. 125 |
|
|||
|
C00027470
|
Piperolactam A
|
CHEMBL387864
|
C457227
|
No. 125 |
|
|||
|
C00025334
|
trans-Feruloyltyramine
/ N-trans-Feruloyltyramine / trans-N-Feruloyltyramine |
CHEMBL206555
CHEMBL451720 |
1 / 4 / 2 | No. 499 |
|
|||
|
C00025788
|
Cepharadione B
|
CHEMBL396085
|
C457230
|
No. 800 |
|
|||
|
C00043208
|
5,6-Dehydro-7,8-dihydromethysticin
|
CHEMBL1376695
|
3 / 0 / 0 | No. 1312 | No. 63 |
|
||
|
C00002741
|
Methyleugenol
/ 4-Allylveratrole / Eugenol methyl ether |
CHEMBL108861
|
C005223
|
12 / 13 / 9 | 3 / 9 | No. 1412 |
|
Human Protein / Gene in interactions
15 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00002741 C00043208 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00025334 | 4 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002741 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002741 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00002741 | 2 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00043208 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00002741 | 0 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00002741 | 3 / 1 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00002741 | 5 / 3 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00002741 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00002741 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002741 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00002741 | 3 / 4 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00002741 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00043208 | 0 / 0 |
3 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 2938 | GSTA1, GST2, GSTA1-1, GTH1 | glutathione S-transferase alpha 1 (EC:2.5.1.18) |
C00002741
|
| 2944 | GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 | glutathione S-transferase mu 1 (EC:2.5.1.18) |
C00002741
|
| 2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00002741
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (17)
| OMIM | preferred title | UniProt |
|---|---|---|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| %606641 | Body mass index; bmi |
P37231
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #137800 | Glioma susceptibility 1; glm1 |
P37231
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #601665 | Obesity |
P37231
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
KEGG DISEASE (11)
| KEGG | name | UniProt |
|---|---|---|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
Diseases related to CTD interactions
9 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D000707 | Anaphylaxis |
C00002741
|
| D001943 | Breast Neoplasms |
C00002741
|
| D003328 | Coronary Thrombosis |
C00002741
|
| D006529 | Hepatomegaly |
C00002741
|
| D006930 | Hyperalgesia |
C00002741
|
| D008113 | Liver Neoplasms |
C00002741
|
| D008114 | Liver Neoplasms, Experimental |
C00002741
|
| D008325 | Mammary Neoplasms, Experimental |
C00002741
|
| D009374 | Neoplasms, Experimental |
C00002741
|