Rubia tinctorum

• Index
• Plant Species
• Metabolite list (9)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Rubia tinctorum
Genus	Rubia
Family	Rubiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Rubia tinctorum
Linked NCBI taxonomy ID	29802
Linked level	species

Family

Family in NCBI taxonomy	Rubiaceae
ID	24966

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (9)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00002785	Alizarin	CHEMBL55814	C010078	44 / 36 / 35	12 / 0	No. 41	No. 62
C00002786	Alizarin 2-methyl ether / 1-Hydroxy-2-methoxyanthraquinone	CHEMBL451977		6 / 9 / 11		No. 41	No. 62
C00002838	Lucidin		C039315			No. 41	No. 62
C00042707	Lucidin-omega-ethyl ether					No. 41	No. 62
C00002862	Rubiadin / 1,3-Dihydroxy-2-methyl-9,10-anthraquinone	CHEMBL251251	C072500			No. 41	No. 62
C00002857	Purpurin	CHEMBL294264	C410870	33 / 27 / 26	5 / 0	No. 41	No. 62
C00003072	Asperuloside	CHEMBL461910 CHEMBL1965021	C077956	1 / 0 / 0		No. 100	No. 36
C00031985	Ophiohayatone B / (-)-Ophiohayatone B / Lucidin 3-O-primeveroside / (-)-Lucidin 3-O-beta-primeveroside	CHEMBL521217	C064334			No. 1320	No. 62
C00002856	Pseudopurpurin					No. 1811	No. 62

Human Protein / Gene in interactions

56 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002785 C00002786 C00002857	1 / 2
P83916	Chromobox protein homolog 1	Unclassified protein	C00002785 C00002857 C00003072	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002785 C00002786 C00002857	4 / 3
O00255	Menin	Unclassified protein	C00002785 C00002786 C00002857	2 / 5
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002785 C00002857	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002785 C00002857	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002785 C00002857	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002785 C00002857	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00002785 C00002857	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002785 C00002857	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00002785 C00002857	1 / 1
P39748	Flap endonuclease 1	Enzyme	C00002785 C00002857	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002785 C00002857	1 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002785 C00002857	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00002785 C00002857	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002785 C00002857	0 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002785 C00002857	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002785 C00002857	2 / 2
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002785 C00002857	3 / 3
Q9Y253	DNA polymerase eta	Enzyme	C00002785 C00002857	1 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00002785 C00002857	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00002785 C00002857	2 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00002785 C00002857	2 / 1
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002785 C00002857	0 / 0
Q99873	Protein arginine N-methyltransferase 1	Enzyme	C00002785	0 / 0
P11308	Transcriptional regulator ERG	Unclassified protein	C00002857	1 / 2
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002857	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00002785	7 / 3
Q99816	Tumor susceptibility gene 101 protein	Unclassified protein	C00002785	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00002785	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002786	1 / 1
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00002785	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00002857	4 / 2
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00002785	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00002857	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002786	0 / 0
O75496	Geminin	Unclassified protein	C00002785	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00002785	5 / 1
P50281	Matrix metalloproteinase-14	M10A	C00002857	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00002785	0 / 0
P10415	Apoptosis regulator Bcl-2	Other cytosolic protein	C00002785	0 / 7
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00002785	0 / 0
Q14145	Kelch-like ECH-associated protein 1	Unclassified protein	C00002785	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00002857	2 / 3
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002786	1 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002857	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002857	1 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00002785	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00002785	4 / 1
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002785	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002785	1 / 4
Q92731	Estrogen receptor beta	NR3A2	C00002785	0 / 1
P03372	Estrogen receptor	NR3A1	C00002785	1 / 1
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002857	0 / 0
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00002785	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00002785	3 / 0

12 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00002785 C00002857
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00002785 C00002857
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00002785 C00002857
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00002785 C00002857
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00002785 C00002857
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00002785
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00002785
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002785
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002785
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002785
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00002785
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00002785

Related Diseases

Diseases related to proteins in ChEMBL interactions