Saussurea lappa

• Index
• Plant Species
• Metabolite list (21)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Saussurea lappa
Genus	Saussurea
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Saussurea costus
Linked NCBI taxonomy ID	324593
Linked level	species

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (21)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003242	(+)-beta-Cyclocostunolide / beta-Cyclocostunolide[3aS-(3aalpha,5abeta,9aalpha,9bbeta)]-Decahydro-5a-methyl-3,9-bis(methylene)-naphtho[1,2-b]furan-2(3H)-one					No. 69	No. 38
C00003240	Costunolide	CHEMBL86416 CHEMBL190377 CHEMBL1575037	C002602	10 / 7 / 15	0 / 3	No. 107	No. 38
C00012737	alpha-Costol / (-)-alpha-Costol / [2R-(2alpha,4aalpha,8abeta)]-1,2,3,4,4a,5,6,8a-Octahydro-4a,8-dimethyl-beta-methylene-2-naphthaleneethanol					No. 151	No. 38
C00012749	(+)-Costol / beta-Costol / Sesquibenihiol / (+)-beta-Costol / Eudesma-4(14),11(13)-dien-12-ol / [2R-(2alpha,4aalpha,8abeta)]-Decahydro-4a-methyl-b,8-bis(methylene)-2-naphthaleneethanol					No. 151	No. 38
C00012168	Dihydrocostunolide / (+)-Dihydrocostunolide / 11betaH,13-Dihydrocostunolide	CHEMBL499003				No. 237
C00020714	Isodehydrocostus lactone	CHEMBL451971				No. 306	No. 38
C00021000	3-3-Epizaluzanin C	CHEMBL461700 CHEMBL462318 CHEMBL1988754				No. 306	No. 38
C00003245	Dehydrocostus lactone	CHEMBL88985 CHEMBL487201 CHEMBL1939730	C083030	1 / 1 / 1		No. 306	No. 38
C00042040	11,13-Epoxyisozaluzanin C					No. 363
C00007191	(+)-8(1)-Hydroxypinoresinol	CHEMBL471274				No. 700	No. 21
C00036308	(+)-Germacrene A					No. 701	No. 38
C00012742	gamma-Costol / (+)-gamma-Costol / (2R-cis)-1,2,3,4,4a,5,6,7-Octahydro-4a,8-dimethyl-beta-methylene-2-naphthaleneethanol					No. 748
C00012743	gamma-Costal / Iso-beta-costal / (+)-gamma-Costal / (2R-cis)- 1,2,3,4,4a,5,6,7-Octahydro-4a,8-dimethyl-alpha-methylene-2-naphthaleneacetaldehyde	CHEMBL186324				No. 748
C00012727	Costic acid / Costus acid	CHEMBL486398				No. 978
C00012006	Saussurea lactone / (all-S)-Hexahydro-7-isopropenyl-3,6-dimethyl-6-vinyl-2(3H)-benzofuranone					No. 1377
C00011507	(E)-6,10-Dimethyl-9-methylene-5-undecen-2-one					No. 2572
C00031500	13-Sulfo-dihydroreynosin					No. 3332
C00032265	Sulfocostunolide B					No. 3332
C00032264	Sulfocostunolide A					No. 3332
C00042039	11,13-Epoxy-3-ketodehydrocostus-lactone					No. 5542
C00044853	Lappadilactone	CHEMBL502902				No. 7017

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P03372	Estrogen receptor	NR3A1	C00003240 C00003245	1 / 1
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003240	1 / 1
Q04206	Transcription factor p65	Transcription Factor	C00003240	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00003240	0 / 3
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00003240	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00003240	2 / 3
O00255	Menin	Unclassified protein	C00003240	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00003240	1 / 2
Q00653	Nuclear factor NF-kappa-B p100 subunit	Transcription Factor	C00003240	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00003240	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions