| Organism name | Salvia amplexicaulis Lam. | 
|---|---|
| Genus | Salvia | 
| Family | Labiatae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Salvia amplexicaulis | 
|---|---|
| Linked NCBI taxonomy ID | 268888 | 
| Linked level | species | 
| Family in NCBI taxonomy | Lamiaceae | 
|---|---|
| ID | 4136 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00019064   | Oleanolic acid / Astrantiagenin C / Virgaureagenin B / 3beta-Hydroxyolean-12-en-28-oic acid | CHEMBL56615 CHEMBL168 CHEMBL180553 CHEMBL365375 CHEMBL486382 CHEMBL1413646 CHEMBL1436454 | D009828 | 30 / 8 / 12 | 21 / 15 | No. 13 | No. 51 |   | 
| C00003558   | Ursolic acid | CHEMBL297810 CHEMBL56048 CHEMBL300594 CHEMBL169 CHEMBL176234 CHEMBL491715 CHEMBL1316667 CHEMBL1555307 CHEMBL1593360 CHEMBL1979720 | C005466 | 47 / 26 / 33 | 15 / 12 | No. 13 | No. 51 |   | 
| C00003737   | alpha-Amyrin / alpha-Amyrine / alpha-Amyrenol | No. 23 | No. 51 |   | ||||
| C00003840   | Salvigenin | CHEMBL376644 | C014049 | No. 35 | No. 15 |   | ||
| C00003672   | Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol | CHEMBL221542 CHEMBL1398443 CHEMBL1875388 | 17 / 19 / 12 | No. 53 | No. 11 |   | ||
| C00029821   | Sitostenone / beta-Sitostenone / Stigmast-4-en-3-one / Stigmast-4-ene-3-one | CHEMBL66926 | No. 53 | No. 11 |   | |||
| C00033565   | Acetyloleanolic acid / Oleanolic acid acetate / 3-O-Acetyloleanolic acid / (+)-Acetyloleanolic acid / (+)-Oleanolic acid acetate / (+)-3-O-Acetyloleanolic acid / 3beta-Acetoxyolean-12-en-28-oic acid | CHEMBL486822 CHEMBL494653 CHEMBL1315416 | C052658 | 1 / 0 / 0 | No. 177 |   | ||
| C00031398   | Sugiol / (+)-Sugiol | CHEMBL195296 | No. 355 |   | ||||
| C00003426   | Ferruginol | CHEMBL197308 | No. 359 | No. 40 |   | |||
| C00036020   | 7-Acetylhorminone / 7alpha-Acetoxyroyleanone | CHEMBL516119 | No. 792 | No. 40 |   | |||
| C00036123   | Horminone / 7alpha-Hydroxyroyleanone | CHEMBL517846 CHEMBL1969546 | C045490 | No. 792 | No. 40 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00003558 C00003672 C00019064 | 0 / 0 | 
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003558 C00003672 C00019064 | 0 / 0 | 
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00003558 C00019064 C00033565 | 0 / 0 | 
| P06746 | DNA polymerase beta | Enzyme | C00003558 C00003672 C00019064 | 0 / 0 | 
| P17706 | Tyrosine-protein phosphatase non-receptor type 2 | Tyr | C00003558 C00019064 | 0 / 1 | 
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00003558 C00019064 | 0 / 0 | 
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00003558 C00019064 | 0 / 1 | 
| P23469 | Receptor-type tyrosine-protein phosphatase epsilon | Receptor tyrosine-protein phosphatase | C00003558 C00019064 | 0 / 0 | 
| P24666 | Low molecular weight phosphotyrosine protein phosphatase | Tyr | C00003558 C00019064 | 0 / 0 | 
| Q8TDU6 | G-protein coupled bile acid receptor 1 | Steroid-like ligand receptor | C00003558 C00019064 | 0 / 0 | 
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00003558 C00019064 | 1 / 4 | 
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003558 C00003672 | 1 / 1 | 
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003558 C00003672 | 0 / 0 | 
| P29350 | Tyrosine-protein phosphatase non-receptor type 6 | Tyr | C00003558 C00019064 | 0 / 0 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00003558 C00019064 | 0 / 3 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00003558 C00019064 | 0 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003558 C00003672 | 0 / 1 | 
| P10586 | Receptor-type tyrosine-protein phosphatase F | Receptor tyrosine-protein phosphatase | C00003558 C00019064 | 0 / 0 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003558 C00003672 | 0 / 1 | 
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00003558 C00019064 | 0 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003558 C00003672 | 1 / 1 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003558 C00003672 | 0 / 0 | 
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00003558 C00019064 | 0 / 0 | 
| P18433 | Receptor-type tyrosine-protein phosphatase alpha | Receptor tyrosine-protein phosphatase | C00003558 C00019064 | 0 / 0 | 
| P15121 | Aldose reductase | Enzyme | C00003558 C00019064 | 0 / 0 | 
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003558 C00003672 | 1 / 0 | 
| Q96RI1 | Bile acid receptor | NR1H4 | C00003558 C00019064 | 0 / 0 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003558 C00019064 | 0 / 0 | 
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00003558 C00019064 | 2 / 2 | 
| P14679 | Tyrosinase | Oxidoreductase | C00003672 | 4 / 2 | 
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003558 | 0 / 0 | 
| P00734 | Prothrombin | S1A | C00003672 | 4 / 2 | 
| Q04206 | Transcription factor p65 | Transcription Factor | C00003558 | 0 / 0 | 
| O15379 | Histone deacetylase 3 | Hydrolase | C00003558 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00019064 | 0 / 0 | 
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00019064 | 0 / 0 | 
| Q9UQL6 | Histone deacetylase 5 | Hydrolase | C00003558 | 0 / 0 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00019064 | 0 / 0 | 
| P03372 | Estrogen receptor | NR3A1 | C00003672 | 1 / 1 | 
| P56524 | Histone deacetylase 4 | Hydrolase | C00003558 | 1 / 1 | 
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00003558 | 0 / 0 | 
| P30305 | M-phase inducer phosphatase 2 | Ser_Thr_Tyr | C00003558 | 0 / 0 | 
| P35228 | Nitric oxide synthase, inducible | Enzyme | C00019064 | 1 / 1 | 
| P28845 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | Enzyme | C00003558 | 1 / 1 | 
| P08183 | Multidrug resistance protein 1 | drug | C00003672 | 1 / 0 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00019064 | 0 / 0 | 
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00019064 | 0 / 0 | 
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00003558 | 0 / 0 | 
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00003558 | 3 / 1 | 
| Q9UBN7 | Histone deacetylase 6 | Hydrolase | C00003558 | 0 / 0 | 
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003672 | 3 / 2 | 
| P04054 | Phospholipase A2 | Enzyme | C00019064 | 0 / 0 | 
| P02545 | Prelamin-A/C | Unclassified protein | C00003558 | 11 / 10 | 
| Q13547 | Histone deacetylase 1 | Hydrolase | C00003558 | 0 / 0 | 
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00003558 | 0 / 0 | 
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003672 | 1 / 1 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00003558 | 1 / 0 | 
| O00255 | Menin | Unclassified protein | C00003558 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003558 | 1 / 2 | 
| Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | Tyr | C00019064 | 4 / 2 | 
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 | 2 / 0 | 
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00003558 | 0 / 0 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | C00003558
                          C00019064 | 
| 7153 | TOP2A, TOP2, TP2A | topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) | C00003558
                          C00019064 | 
| 7150 | TOP1, TOPI | topoisomerase (DNA) I (EC:5.99.1.2) | C00003558
                          C00019064 | 
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 | C00003558
                          C00019064 | 
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | C00003558
                          C00019064 | 
| 177 | AGER, RAGE | advanced glycosylation end product-specific receptor | C00019064 | 
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic | C00003558 | 
| 1557 | CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 | cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) | C00003558 | 
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 | C00003558 | 
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) | C00003558 | 
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) | C00003558 | 
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | C00003558 | 
| 7040 | TGFB1, CED, DPD1, LAP, TGFB, TGFbeta | transforming growth factor, beta 1 | C00003558 | 
| 581 | BAX, BCL2L4 | BCL2-associated X protein | C00003558 | 
| 578 | BAK1, BAK, BAK-LIKE, BCL2L7, CDN1 | BCL2-antagonist/killer 1 | C00003558 | 
| 9131 | AIFM1, AIF, CMTX4, COWCK, COXPD6, PDCD8 | apoptosis-inducing factor, mitochondrion-associated, 1 | C00003558 | 
| 847 | CAT | catalase (EC:1.11.1.6) | C00019064 | 
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 | C00019064 | 
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | C00019064 | 
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | C00019064 | 
| 3065 | HDAC1, GON-10, HD1, RPD3, RPD3L1 | histone deacetylase 1 (EC:3.5.1.98) | C00019064 | 
| 3146 | HMGB1, HMG1, HMG3, SBP-1 | high mobility group box 1 | C00019064 | 
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) | C00019064 | 
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) | C00019064 | 
| 4233 | MET, AUTS9, HGFR, RCCP2, c-Met | met proto-oncogene (EC:2.7.10.1) | C00019064 | 
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 | C00019064 | 
| 5052 | PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2 | peroxiredoxin 1 (EC:1.11.1.15) | C00019064 | 
| 5728 | PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 | phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) | C00019064 | 
| 6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E | C00019064 | 
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor | C00019064 | 
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 | C00019064 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #103470 | Albinism, ocular, with sensorineural deafness | P14679 | 
| #203100 | Albinism, oculocutaneous, type ia; oca1a | P14679 | 
| #606952 | Albinism, oculocutaneous, type ib; oca1b | P14679 | 
| #218030 | Apparent mineralocorticoid excess; ame | P80365 | 
| #613546 | Aromatase deficiency | P11511 | 
| #139300 | Aromatase excess syndrome; aexs | P11511 | 
| #600430 | Brachydactyly-mental retardation syndrome; bdmr | P56524 | 
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a | P02545 | 
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism | P02545 | 
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 | P02545 | 
| #604931 | Cortisone reductase deficiency 1; cortrd1 | P28845 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 | P02545 | 
| #615363 | Estrogen resistance; estrr | P03372 | 
| #137800 | Glioma susceptibility 1; glm1 | O75874 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #610140 | Heart-hand syndrome, slovenian type | P02545 | 
| #176670 | Hutchinson-gilford progeria syndrome; hgps | P02545 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #603373 | Hyperthyroidism, familial gestational | P16473 | 
| #609152 | Hyperthyroidism, nonautoimmune | P16473 | 
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 | P16473 | 
| #612244 | Inflammatory bowel disease 13; ibd13 | P08183 | 
| #607785 | Juvenile myelomonocytic leukemia; jmml | Q06124 | 
| #151100 | Leopard syndrome 1 | Q06124 | 
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 | P02545 | 
| #611162 | Malaria, susceptibility to | P35228 | 
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada | P02545 | 
| #156250 | Metachondromatosis; metcds | Q06124 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #613205 | Muscular dystrophy, congenital, lmna-related | P02545 | 
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b | P02545 | 
| #163950 | Noonan syndrome 1; ns1 | Q06124 | 
| #601399 | Platelet disorder, familial, with associated myeloid malignancy | Q01196 | 
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 | P00734 | 
| #613679 | Prothrombin deficiency, congenital | P00734 | 
| #275210 | Restrictive dermopathy, lethal | P02545 | 
| #604906 | Schizophrenia 9; sczd9 | P49798 | 
| #181500 | Schizophrenia; sczd | P49798 | 
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 | P14679 | 
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 | Q9NUW8 | 
| #601367 | Stroke, ischemic | P00734 | 
| #188050 | Thrombophilia due to thrombin defect; thph1 | P00734 | 
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth | P10828 | 
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth | P10828 | 
| #145650 | Thyroid hormone resistance, selective pituitary; prth | P10828 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00223 | Inherited thrombophilia | P00734
                            (related) | 
| H01254 | Congenital prothrombin deficiency | P00734
                            (related) | 
| H00264 | Charcot-Marie-Tooth disease (CMT) | P02545
                            (related) | 
| H00294 | Dilated cardiomyopathy (DCM) | P02545
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P02545
                            (related) | 
| H00563 | Emery-Dreifuss muscular dystrophy | P02545
                            (related) | 
| H00590 | Congenital muscular dystrophies (CMD/MDC) | P02545
                            (related) | 
| H00593 | Limb-girdle muscular dystrophy (LGMD) | P02545
                            (related) | 
| H00601 | Hutchinson-Gilford progeria syndrome | P02545
                            (related) | 
| H00663 | Restrictive dermopathy | P02545
                            (related) | 
| H00665 | Mandibuloacral dysplasia | P02545
                            (related) | 
| H01216 | Left ventricular noncompaction (LVNC) | P02545
                            (related) | 
| H00026 | Endometrial Cancer | P03372
                            (marker) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00249 | Thyroid hormone resistance syndrome | P10828
                            (related) | 
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) | P11511
                            (related) | 
| H00794 | Aromatase excess syndrome | P11511
                            (related) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H00168 | Oculocutaneous albinism (OCA) | P14679
                            (related) | 
| H00038 | Malignant melanoma | P14679
                            (marker) | 
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) | P16473
                            (related) | 
| H01269 | Congenital hyperthyroidism | P16473
                            (related) | 
| H00408 | Type I diabetes mellitus | P17706
                            (related) | 
| H01111 | Cortisone reductase deficiency (CRD) | P28845
                            (related) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00017 | Esophageal cancer | P35228
                            (related) P35354 (related) | 
| H00025 | Penile cancer | P35354
                            (related) | 
| H00046 | Cholangiocarcinoma | P35354
                            (related) | 
| H00561 | Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome | P56524
                            (related) | 
| H00259 | Apparent mineralocorticoid excess syndrome | P80365
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q01196
                            (related) Q01196 (marker) Q03164 (related) Q03164 (marker) | 
| H00003 | Acute myeloid leukemia (AML) | Q01196
                            (related) Q01196 (marker) Q13951 (marker) | 
| H00004 | Chronic myeloid leukemia (CML) | Q01196
                            (related) | 
| H00978 | Thrombocytopenia (THC) | Q01196
                            (related) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00523 | Noonan syndrome and related disorders | Q06124
                            (related) | 
| H01018 | Metachondromatosis | Q06124
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q9NUW8
                            (related) | 
| MESH or OMIM | name | KNApSAcK metabolite | 
|---|---|---|
| D006949 | Hyperlipidemias | C00003558 C00019064 | 
| D009369 | Neoplasms | C00003558 C00019064 | 
| D017202 | Myocardial Ischemia | C00003558 C00019064 | 
| D008103 | Liver Cirrhosis | C00003558 C00019064 | 
| D007249 | Inflammation | C00003558 C00019064 | 
| D012878 | Skin Neoplasms | C00003558 | 
| D006965 | Hyperplasia | C00003558 | 
| D006943 | Hyperglycemia | C00003558 | 
| D003921 | Diabetes Mellitus, Experimental | C00003558 | 
| D002471 | Cell Transformation, Neoplastic | C00003558 | 
| D006528 | Carcinoma, Hepatocellular | C00003558 | 
| D001284 | Atrophy | C00003558 | 
| D002252 | Carbon Tetrachloride Poisoning | C00019064 | 
| D056486 | Drug-Induced Liver Injury | C00019064 | 
| D050171 | Dyslipidemias | C00019064 | 
| D018149 | Glucose Intolerance | C00019064 | 
| D007674 | Kidney Diseases | C00019064 | 
| D008106 | Liver Cirrhosis, Experimental | C00019064 | 
| D008107 | Liver Diseases | C00019064 | 
| D009765 | Obesity | C00019064 | 
| D011041 | Poisoning | C00019064 | 
| D011230 | Precancerous Conditions | C00019064 |