KEGG   REACTION: R03875Help
Entry
R03875                      Reaction                               

Definition
Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine
Equation
Reaction class
RC00003  C00019_C00021
RC00060  C02188_C05544
Enzyme
2.1.1.59        2.1.1.60        2.1.1.354       2.1.1.355       
2.1.1.356       2.1.1.357       2.1.1.359       2.1.1.360       
2.1.1.361
Pathway
rn00310  Lysine degradation
rn01100  Metabolic pathways
Orthology
K06101  [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
K09186  [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
K09187  [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
K09188  [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
K09189  [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354]
K11419  [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11420  [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11421  [histone H3]-lysine9 N-trimethyltransferase SETDB1 [EC:2.1.1.355]
K11422  [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11424  [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357]
K11425  [histone H3]-lysine36 N-dimethyltransferase NSD3 [EC:2.1.1.357]
K11426  [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11427  [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
K11428  [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
K11430  [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K11431  [histone H3]-lysine4 N-trimethyltransferase SETD7 [EC:2.1.1.354]
K11432  [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
K14959  [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
K15588  [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
K17451  [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356]
K18494  [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355]
K18804  [cytochrome c]-lysine N-methyltransferase [EC:2.1.1.59]
K18826  calmodulin-lysine N-methyltransferase [EC:2.1.1.60]
K20795  [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361]
K20796  [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
K22748  [histone H3]-lysine4 N-trimethyltransferase ATXR3 [EC:2.1.1.354]
K23700  [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359]
Other DBs
RHEA: 51739

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