Scoparia dulcis L.
Species
KNApSAcK Entry
| Organism name | Scoparia dulcis L. |
|---|---|
| Genus | Scoparia |
| Family | Plantaginaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Scoparia dulcis |
|---|---|
| Linked NCBI taxonomy ID | 107240 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Plantaginaceae |
|---|---|
| ID | 156152 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Natural Activity
List (93)
| Species | Activity |
|---|---|
| Scoparia dulcis L. | Abortifacient |
| Scoparia dulcis L. | Abortifacient |
| Scoparia dulcis L. | Analgesic |
| Scoparia dulcis L. | Analgesic |
| Scoparia dulcis L. | Antidiabetic |
| Scoparia dulcis L. | Antiedemic |
| Scoparia dulcis L. | Antiemetic |
| Scoparia dulcis L. | Antifilarial |
| Scoparia dulcis L. | Antiherpetic |
| Scoparia dulcis L. | Antiherpetic |
| Scoparia dulcis L. | Antiinflammatory |
| Scoparia dulcis L. | Antileukemic |
| Scoparia dulcis L. | Antioxidant |
| Scoparia dulcis L. | Antiplaque |
| Scoparia dulcis L. | Antiplaque |
| Scoparia dulcis L. | Antipyretic |
| Scoparia dulcis L. | Antiradicular |
| Scoparia dulcis L. | Antiseptic |
| Scoparia dulcis L. | Antiseptic |
| Scoparia dulcis L. | Antispasmodic |
| Scoparia dulcis L. | Antitumor |
| Scoparia dulcis L. | Antitumor |
| Scoparia dulcis L. | Antitussive |
| Scoparia dulcis L. | Antiulcer |
| Scoparia dulcis L. | Antiulcer |
| Scoparia dulcis L. | Antiviral |
| Scoparia dulcis L. | Antiviral |
| Scoparia dulcis L. | Aphrodisiac |
| Scoparia dulcis L. | Aphrodisiac |
| Scoparia dulcis L. | Astringent |
| Scoparia dulcis L. | Astringent |
| Scoparia dulcis L. | Bactericide |
| Scoparia dulcis L. | Beta-Glucuronidase Inhibitor |
| Scoparia dulcis L. | Beta-Glucuronidase-Inhibitor |
| Scoparia dulcis L. | Cardiotonic |
| Scoparia dulcis L. | Cholagogue |
| Scoparia dulcis L. | CNS-Depressant |
| Scoparia dulcis L. | Collyrium |
| Scoparia dulcis L. | Contraceptive |
| Scoparia dulcis L. | Contraceptive |
| Scoparia dulcis L. | Cytotoxic |
| Scoparia dulcis L. | Cytotoxic |
| Scoparia dulcis L. | Decongestant |
| Scoparia dulcis L. | Dentifrice |
| Scoparia dulcis L. | Depurative |
| Scoparia dulcis L. | Depurative |
| Scoparia dulcis L. | Detoxicant |
| Scoparia dulcis L. | Diaphoretic |
| Scoparia dulcis L. | Diaphoretic |
| Scoparia dulcis L. | Digestive |
| Scoparia dulcis L. | Diuretic |
| Scoparia dulcis L. | Emetic |
| Scoparia dulcis L. | Emetic |
| Scoparia dulcis L. | Emmenagogue |
| Scoparia dulcis L. | Emollient |
| Scoparia dulcis L. | Emollient |
| Scoparia dulcis L. | Expectorant |
| Scoparia dulcis L. | Febrifuge |
| Scoparia dulcis L. | Fungicide |
| Scoparia dulcis L. | Gastroprotective |
| Scoparia dulcis L. | Gastroprotective |
| Scoparia dulcis L. | H+-ATPase-Inhibitor |
| Scoparia dulcis L. | Hypertensive |
| Scoparia dulcis L. | Hypoglycemic |
| Scoparia dulcis L. | Hypotensive |
| Scoparia dulcis L. | Inotropic |
| Scoparia dulcis L. | Insecticide |
| Scoparia dulcis L. | Insulinogenic |
| Scoparia dulcis L. | K+-ATPase-Inhibitor |
| Scoparia dulcis L. | Litholytic |
| Scoparia dulcis L. | Mucolytic |
| Scoparia dulcis L. | Mutagenic |
| Scoparia dulcis L. | Mutagenic |
| Scoparia dulcis L. | Myorelaxant |
| Scoparia dulcis L. | Neurotropic |
| Scoparia dulcis L. | Orexigenic |
| Scoparia dulcis L. | Orexigenic |
| Scoparia dulcis L. | Pectoral |
| Scoparia dulcis L. | Pediculicide |
| Scoparia dulcis L. | Pediculicide |
| Scoparia dulcis L. | Plasmodicide |
| Scoparia dulcis L. | Pulicide |
| Scoparia dulcis L. | Pulicide |
| Scoparia dulcis L. | Secretagogue |
| Scoparia dulcis L. | Sedative |
| Scoparia dulcis L. | Stomachic |
| Scoparia dulcis L. | Sympathomimetic |
| Scoparia dulcis L. | Sympathomimetic |
| Scoparia dulcis L. | Tonic |
| Scoparia dulcis L. | Tonic |
| Scoparia dulcis L. | Vermifuge |
| Scoparia dulcis L. | Vulnerary |
| Scoparia dulcis L. | Vulnerary |
Metabolite list (15)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00004569
|
Jaranol
/ Kumatakenin / Kumatakillin / Kaempferol 3,7-O-dimethyl ether / 5,4'-Dihydroxy-3,7-dimethoxyflavone / 5-Hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL349724
|
No. 3 | No. 15 |
|
|||
|
C00003820
|
Acacetin
/ Apigenin 4'-methyl ether / 5,7-Dihydroxy-4'-methoxyflavone |
CHEMBL243664
|
C023717
|
37 / 55 / 72 | 5 / 0 | No. 3 | No. 15 |
|
|
C00003749
|
Lupeol
/ Lupenol / (+)-Lupenol |
CHEMBL289191
CHEMBL459702 |
C010480
|
3 / 0 / 0 | 2 / 6 | No. 23 | No. 51 |
|
|
C00003741
|
Betulinic acid
|
CHEMBL269277
CHEMBL71690 CHEMBL519059 CHEMBL1318530 CHEMBL2005635 |
C002070
|
34 / 17 / 14 | 10 / 2 | No. 23 | No. 51 |
|
|
C00024032
|
Scopadulcic Acid A
|
CHEMBL464656
|
No. 997 |
|
||||
|
C00030524
|
iso-Dulcinol
|
CHEMBL453025
|
No. 997 |
|
||||
|
C00030160
|
Dulcinol
/ Scopadulciol |
No. 997 |
|
|||||
|
C00029527
|
4-epi-Scopadulcic acid B
|
CHEMBL267008
CHEMBL12514 CHEMBL318885 CHEMBL509623 |
No. 997 |
|
||||
|
C00031322
|
Scopadulcic acid C
|
No. 997 |
|
|||||
|
C00030824
|
Nirtetralin
/ (+)-Nirtetralin |
CHEMBL453822
|
C475933
|
2 / 4 / 4 | No. 1105 |
|
||
|
C00030823
|
Niranthin
|
C475932
|
No. 1232 | No. 21 |
|
|||
|
C00024034
|
Scoparic Acid B
|
CHEMBL478592
|
No. 1982 |
|
||||
|
C00024033
|
Scoparic acid A
|
CHEMBL478591
|
C055030
|
No. 1982 |
|
|||
|
C00024035
|
Scoparic Acid C
|
CHEMBL478766
|
No. 1982 |
|
||||
|
C00029643
|
Adrenalin
|
CHEMBL679
CHEMBL42280 CHEMBL227634 CHEMBL1740 |
D004837
|
126 / 58 / 55 | 34 / 171 | No. 3197 |
|
Human Protein / Gene in interactions
175 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003741 C00003820 C00029643 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003741 C00003820 C00029643 | 0 / 1 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00003741 C00003820 C00029643 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003741 C00003820 C00029643 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003741 C00003820 C00029643 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003741 C00003820 C00029643 | 0 / 1 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00003820 C00029643 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003820 C00029643 | 4 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00003741 C00029643 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00003820 C00029643 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00003820 C00029643 | 1 / 1 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003820 C00029643 | 1 / 2 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00029643 C00030824 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003820 C00029643 | 1 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003820 C00029643 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00003741 C00003749 | 0 / 0 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00003741 C00003749 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00003820 C00029643 | 1 / 8 |
| O00255 | Menin | Unclassified protein | C00003820 C00029643 | 2 / 5 |
| P02545 | Prelamin-A/C | Unclassified protein | C00003741 C00003820 | 11 / 10 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00003741 C00003820 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00029643 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00029643 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00003820 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00029643 | 2 / 2 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00029643 | 0 / 0 |
| Q8TDU6 | G-protein coupled bile acid receptor 1 | Steroid-like ligand receptor | C00003741 | 0 / 0 |
| O15245 | Solute carrier family 22 member 1 | Drug uniporter | C00029643 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00029643 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00029643 | 0 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003749 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00029643 | 3 / 2 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00029643 | 1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00029643 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00029643 | 1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00029643 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00029643 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00029643 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00029643 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00029643 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00029643 | 0 / 0 |
| Q02156 | Protein kinase C epsilon type | Eta | C00003741 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00003820 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00029643 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00029643 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00029643 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00029643 | 0 / 0 |
| P15559 | NAD(P)H dehydrogenase [quinone] 1 | Enzyme | C00003741 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00029643 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00029643 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00003741 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00029643 | 2 / 3 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00029643 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00029643 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00029643 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00029643 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00029643 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00029643 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00029643 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00029643 | 0 / 0 |
| Q9Y3R4 | Sialidase-2 | Enzyme | C00003820 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00029643 | 1 / 1 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00029643 | 0 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00029643 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00029643 | 1 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00029643 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00029643 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00029643 | 1 / 2 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00029643 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00029643 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00029643 | 0 / 0 |
| P08151 | Zinc finger protein GLI1 | Unclassified protein | C00003741 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003820 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00003741 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00003820 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00003820 | 4 / 2 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00029643 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00029643 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00029643 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00029643 | 0 / 0 |
| P35348 | Alpha-1A adrenergic receptor | Adrenergic receptor | C00029643 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00029643 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00029643 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00029643 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00029643 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00003741 | 0 / 0 |
| P24530 | Endothelin B receptor | Endothelin receptor | C00030824 | 4 / 4 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00029643 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00029643 | 1 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00029643 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003741 | 0 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00029643 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00029643 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00029643 | 1 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00003741 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00029643 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00029643 | 0 / 0 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00003741 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00003741 | 1 / 1 |
| P08246 | Neutrophil elastase | S1A | C00029643 | 2 / 1 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00003741 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00029643 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00029643 | 2 / 2 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00029643 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00029643 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00029643 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00029643 | 2 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00003820 | 5 / 3 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00029643 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00029643 | 1 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00003820 | 4 / 4 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00029643 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00029643 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00029643 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00029643 | 0 / 0 |
| P04745 | Alpha-amylase 1 | Enzyme | C00003820 | 0 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00029643 | 2 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00003741 | 0 / 0 |
| Q13133 | Oxysterols receptor LXR-alpha | NR1H3 | C00003741 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00029643 | 1 / 0 |
| P50750 | Cyclin-dependent kinase 9 | Cdk9 | C00003820 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00029643 | 0 / 3 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00029643 | 2 / 1 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00029643 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00029643 | 0 / 1 |
| P55055 | Oxysterols receptor LXR-beta | NR1H3 | C00003741 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00029643 | 3 / 3 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00003820 | 2 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00003820 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00003820 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00029643 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00029643 | 1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00029643 | 1 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00029643 | 1 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00029643 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00029643 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00029643 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00029643 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00029643 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00029643 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00029643 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00003741 | 0 / 0 |
| P05771 | Protein kinase C beta type | Alpha | C00003741 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00003741 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003741 | 2 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00029643 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00003820 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00029643 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00003820 | 4 / 1 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00029643 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00029643 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00003820 | 3 / 4 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00029643 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00029643 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00029643 | 0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00003820 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00029643 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00029643 | 1 / 1 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00029643 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00029643 | 0 / 1 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00029643 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00029643 | 1 / 1 |
| P49336 | Cyclin-dependent kinase 8 | Cdk8 | C00003820 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00029643 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00029643 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00029643 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00003820 | 7 / 37 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00003741 | 1 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00003741 | 0 / 0 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00029643 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00029643 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00029643 | 1 / 4 |
| Q9UBT2 | SUMO-activating enzyme subunit 2 | Enzyme | C00003741 | 0 / 0 |
| Q9UBE0 | SUMO-activating enzyme subunit 1 | Unclassified protein | C00003741 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00003820 | 1 / 1 |
48 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00003741
C00029643
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00003741
C00029643
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00003741
C00029643
|
| 154 | ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR | adrenoceptor beta 2, surface |
C00029643
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00003741
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00003741
|
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 |
C00003741
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00003741
|
| 7150 | TOP1, TOPI | topoisomerase (DNA) I (EC:5.99.1.2) |
C00003741
|
| 7153 | TOP2A, TOP2, TP2A | topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) |
C00003741
|
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00003749
|
| 5728 | PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 | phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) |
C00003749
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00003820
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00003820
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00003820
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00003820
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00003820
|
| 148 | ADRA1A, ADRA1C, ADRA1L1, ALPHA1AAR | adrenoceptor alpha 1A |
C00029643
|
| 147 | ADRA1B, ADRA1, ALPHA1BAR | adrenoceptor alpha 1B |
C00029643
|
| 146 | ADRA1D, ADRA1, ADRA1A, ADRA1R, ALPHA1, DAR, dJ779E11.2 | adrenoceptor alpha 1D |
C00029643
|
| 150 | ADRA2A, ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32 | adrenoceptor alpha 2A |
C00029643
|
| 151 | ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR | adrenoceptor alpha 2B |
C00029643
|
| 152 | ADRA2C, ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR | adrenoceptor alpha 2C |
C00029643
|
| 153 | ADRB1, ADRB1R, B1AR, BETA1AR, RHR | adrenoceptor beta 1 |
C00029643
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00003741
|
| 155 | ADRB3, BETA3AR | adrenoceptor beta 3 |
C00029643
|
| 156 | ADRBK1, BARK1, BETA-ARK1, GRK2 | adrenergic, beta, receptor kinase 1 (EC:2.7.11.15) |
C00029643
|
| 760 | CA2, CA-II, CAC, CAII, Car2 | carbonic anhydrase II (EC:4.2.1.1) |
C00029643
|
| 6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 |
C00029643
|
| 1139 | CHRNA7, CHRNA7-2, NACHRA7 | cholinergic receptor, nicotinic, alpha 7 (neuronal) |
C00029643
|
| 1312 | COMT | catechol-O-methyltransferase (EC:2.1.1.6) |
C00029643
|
| 1513 | CTSK, CTS02, CTSO, CTSO1, CTSO2, PKND, PYCD | cathepsin K (EC:3.4.22.38) |
C00029643
|
| 355 | FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 | Fas cell surface death receptor |
C00029643
|
| 356 | FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 | Fas ligand (TNF superfamily, member 6) |
C00029643
|
| 2869 | GRK5, GPRK5 | G protein-coupled receptor kinase 5 (EC:2.7.11.16) |
C00029643
|
| 3586 | IL10, CSIF, GVHDS, IL-10, IL10A, TGIF | interleukin 10 |
C00029643
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00029643
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00029643
|
| 3630 | INS, IDDM2, ILPR, IRDN, MODY10 | insulin |
C00029643
|
| 3673 | ITGA2, BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
C00029643
|
| 3685 | ITGAV, CD51, MSK8, VNRA, VTNR | integrin, alpha V |
C00029643
|
| 3991 | LIPE, HSL, LHS | lipase, hormone-sensitive (EC:3.1.1.79) |
C00029643
|
| 5027 | P2RX7, P2X7 | purinergic receptor P2X, ligand-gated ion channel, 7 |
C00029643
|
| 5972 | REN, HNFJ2 | renin (EC:3.4.23.15) |
C00029643
|
| 6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00029643
|
| 6648 | SOD2, IPOB, MNSOD, MVCD6 | superoxide dismutase 2, mitochondrial (EC:1.15.1.1) |
C00029643
|
| 6818 | SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) |
C00029643
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00029643
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (103)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #600501 | Abcd syndrome; abcds |
P24530
|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P18054
P84022 |
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
P18054 |
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 P37231 |
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #142623 | Hirschsprung disease, susceptibility to, 1; hscr1 |
P24530
|
| #600155 | Hirschsprung disease, susceptibility to, 2; hscr2 |
P24530
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P38398 |
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277580 | Waardenburg syndrome, type 4a; ws4a |
P24530
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (101)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) P38398 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) P38398 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00054 | Nasopharyngeal cancer |
P24530
(related)
|
| H00759 | Waardenburg syndrome (WS) |
P24530
(related)
|
| H00823 | ABCD syndrome |
P24530
(related)
|
| H00910 | Hirschsprung disease (HD) |
P24530
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
178 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D009202 | Cardiomyopathies |
C00003749
C00029643 |
| D011655 | Pulmonary Embolism |
C00029643
|
| D006528 | Carcinoma, Hepatocellular |
C00003749
|
| D008103 | Liver Cirrhosis |
C00003741
|
| D006937 | Hypercholesterolemia |
C00003749
|
| D009374 | Neoplasms, Experimental |
C00003749
|
| D012878 | Skin Neoplasms |
C00003749
|
| D014947 | Wounds and Injuries |
C00003749
|
| D000138 | Acidosis |
C00029643
|
| D000140 | Acidosis, Lactic |
C00029643
|
| C538173 | Acquired angioedema |
C00029643
|
| D058186 | Acute Kidney Injury |
C00029643
|
| C538231 | Adenocarcinoma of lung |
C00029643
|
| D000402 | Airway Obstruction |
C00029643
|
| D000647 | Amnesia |
C00029643
|
| D000707 | Anaphylaxis |
C00029643
|
| D017542 | Aneurysm, Ruptured |
C00029643
|
| D000787 | Angina Pectoris |
C00029643
|
| D000799 | Angioedema |
C00029643
|
| D000855 | Anorexia |
C00029643
|
| D001008 | Anxiety Disorders |
C00029643
|
| D001037 | Aphasia |
C00029643
|
| D001044 | Aphonia |
C00029643
|
| D001049 | Apnea |
C00029643
|
| D001145 | Arrhythmias, Cardiac |
C00029643
|
| D001146 | Arrhythmia, Sinus |
C00029643
|
| D018771 | Arthralgia |
C00029643
|
| D001249 | Asthma |
C00029643
|
| D001259 | Ataxia |
C00029643
|
| D050197 | Atherosclerosis |
C00029643
|
| D001281 | Atrial Fibrillation |
C00029643
|
| D054537 | Atrioventricular Block |
C00029643
|
| D001416 | Back Pain |
C00029643
|
| D001763 | Blepharoptosis |
C00029643
|
| D016063 | Blood Loss, Surgical |
C00029643
|
| D001919 | Bradycardia |
C00029643
|
| D002545 | Brain Ischemia |
C00029643
|
| D020526 | Brain Stem Infarctions |
C00029643
|
| D001986 | Bronchial Spasm |
C00029643
|
| D001988 | Bronchiolitis |
C00029643
|
| D010244 | Bulbar Palsy, Progressive |
C00029643
|
| D002303 | Cardiac Output, Low |
C00029643
|
| D002311 | Cardiomyopathy, Dilated |
C00029643
|
| D016893 | Carotid Stenosis |
C00029643
|
| D002543 | Cerebral Hemorrhage |
C00029643
|
| D002544 | Cerebral Infarction |
C00029643
|
| D002637 | Chest Pain |
C00029643
|
| D019970 | Cocaine-Related Disorders |
C00029643
|
| D003085 | Colic |
C00029643
|
| D000013 | Congenital Abnormalities |
C00029643
|
| D003324 | Coronary Artery Disease |
C00029643
|
| D003328 | Coronary Thrombosis |
C00029643
|
| D003329 | Coronary Vasospasm |
C00029643
|
| D003371 | Cough |
C00029643
|
| D003440 | Croup |
C00029643
|
| D003556 | Cystitis |
C00029643
|
| D003645 | Death, Sudden |
C00029643
|
| D016757 | Death, Sudden, Cardiac |
C00029643
|
| D004172 | Diplopia |
C00029643
|
| D004211 | Disseminated Intravascular Coagulation |
C00029643
|
| D004244 | Dizziness |
C00029643
|
| D004342 | Drug Hypersensitivity |
C00029643
|
| D062787 | Drug Overdose |
C00029643
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00029643
|
| D004387 | Dupuytren Contracture |
C00029643
|
| D004401 | Dysarthria |
C00029643
|
| D004417 | Dyspnea |
C00029643
|
| D004487 | Edema |
C00029643
|
| D004827 | Epilepsy |
C00029643
|
| D004830 | Epilepsy, Tonic-Clonic |
C00029643
|
| D005119 | Extravasation of Diagnostic and Therapeutic Materials |
C00029643
|
| D015673 | Fatigue Syndrome, Chronic |
C00029643
|
| D005512 | Food Hypersensitivity |
C00029643
|
| D006471 | Gastrointestinal Hemorrhage |
C00029643
|
| D005891 | Gingivitis |
C00029643
|
| D005901 | Glaucoma |
C00029643
|
| D005902 | Glaucoma, Open-Angle |
C00029643
|
| D006261 | Headache |
C00029643
|
| D034381 | Hearing Loss |
C00029643
|
| D006319 | Hearing Loss, Sensorineural |
C00029643
|
| D006323 | Heart Arrest |
C00029643
|
| D006327 | Heart Block |
C00029643
|
| D006331 | Heart Diseases |
C00029643
|
| D006333 | Heart Failure |
C00029643
|
| D006470 | Hemorrhage |
C00029643
|
| D006732 | Horner Syndrome |
C00029643
|
| D006930 | Hyperalgesia |
C00029643
|
| D006934 | Hypercalcemia |
C00029643
|
| D006940 | Hyperemia |
C00029643
|
| D006943 | Hyperglycemia |
C00029643
|
| D006945 | Hyperhidrosis |
C00029643
|
| D006947 | Hyperkalemia |
C00029643
|
| D006967 | Hypersensitivity |
C00029643
|
| D006973 | Hypertension |
C00029643
|
| D007008 | Hypokalemia |
C00029643
|
| D007022 | Hypotension |
C00029643
|
| D007249 | Inflammation |
C00029643
|
| D007299 | Insect Bites and Stings |
C00029643
|
| D007431 | Intraoperative Complications |
C00029643
|
| D007511 | Ischemia |
C00029643
|
| D048949 | Labor Pain |
C00029643
|
| D007819 | Laryngeal Edema |
C00029643
|
| D007964 | Leukocytosis |
C00029643
|
| D008133 | Long QT Syndrome |
C00029643
|
| D008269 | Macular Edema |
C00029643
|
| D008275 | Magnesium Deficiency |
C00029643
|
| D009127 | Muscle Rigidity |
C00029643
|
| D009135 | Muscular Diseases |
C00029643
|
| D009203 | Myocardial Infarction |
C00029643
|
| D017202 | Myocardial Ischemia |
C00029643
|
| D017682 | Myocardial Stunning |
C00029643
|
| D009205 | Myocarditis |
C00029643
|
| D009325 | Nausea |
C00029643
|
| D009336 | Necrosis |
C00029643
|
| D009422 | Nervous System Diseases |
C00029643
|
| D009503 | Neutropenia |
C00029643
|
| D009798 | Ocular Hypertension |
C00029643
|
| D018917 | Optic Neuropathy, Ischemic |
C00029643
|
| D010146 | Pain |
C00029643
|
| D010149 | Pain, Postoperative |
C00029643
|
| D010167 | Pallor |
C00029643
|
| D016584 | Panic Disorder |
C00029643
|
| D010243 | Paralysis |
C00029643
|
| D010292 | Paresthesia |
C00029643
|
| D010673 | Pheochromocytoma |
C00029643
|
| D011183 | Postoperative Complications |
C00029643
|
| D020250 | Postoperative Nausea and Vomiting |
C00029643
|
| D011297 | Prenatal Exposure Delayed Effects |
C00029643
|
| D011317 | Priapism |
C00029643
|
| D011537 | Pruritus |
C00029643
|
| D011595 | Psychomotor Agitation |
C00029643
|
| D029424 | Pulmonary Disease, Chronic Obstructive |
C00029643
|
| D011654 | Pulmonary Edema |
C00029643
|
| D008545 | Melanoma |
C00003741
|
| D012019 | Reflex Sympathetic Dystrophy |
C00029643
|
| D051437 | Renal Insufficiency |
C00029643
|
| D015427 | Reperfusion Injury |
C00029643
|
| D012120 | Respiration Disorders |
C00029643
|
| D012131 | Respiratory Insufficiency |
C00029643
|
| D012133 | Respiratory Paralysis |
C00029643
|
| D012135 | Respiratory Sounds |
C00029643
|
| D015356 | Retinal Artery Occlusion |
C00029643
|
| D012164 | Retinal Diseases |
C00029643
|
| D012206 | Rhabdomyolysis |
C00029643
|
| D012607 | Scotoma |
C00029643
|
| D012640 | Seizures |
C00029643
|
| D012769 | Shock |
C00029643
|
| D012770 | Shock, Cardiogenic |
C00029643
|
| D012892 | Sleep Deprivation |
C00029643
|
| D013159 | Splenic Infarction |
C00029643
|
| D013224 | Status Asthmaticus |
C00029643
|
| D013276 | Stomach Ulcer |
C00029643
|
| D013345 | Subarachnoid Hemorrhage |
C00029643
|
| D013575 | Syncope |
C00029643
|
| D019462 | Syncope, Vasovagal |
C00029643
|
| D013610 | Tachycardia |
C00029643
|
| D013616 | Tachycardia, Sinus |
C00029643
|
| D013617 | Tachycardia, Supraventricular |
C00029643
|
| D017180 | Tachycardia, Ventricular |
C00029643
|
| D054549 | Takotsubo Cardiomyopathy |
C00029643
|
| D013921 | Thrombocytopenia |
C00029643
|
| D013923 | Thromboembolism |
C00029643
|
| D013927 | Thrombosis |
C00029643
|
| D014012 | Tinnitus |
C00029643
|
| D016171 | Torsades de Pointes |
C00029643
|
| D014202 | Tremor |
C00029643
|
| D014456 | Ulcer |
C00029643
|
| D014474 | Unconsciousness |
C00029643
|
| D016055 | Urinary Retention |
C00029643
|
| D014581 | Urticaria |
C00029643
|
| D014652 | Vascular Diseases |
C00029643
|
| D018754 | Ventricular Dysfunction |
C00029643
|
| D018487 | Ventricular Dysfunction, Left |
C00029643
|
| D014693 | Ventricular Fibrillation |
C00029643
|
| D018879 | Ventricular Premature Complexes |
C00029643
|
| D014786 | Vision Disorders |
C00029643
|
| D015354 | Vision, Low |
C00029643
|
| D014839 | Vomiting |
C00029643
|