Tordylium apulum

• Index
• Plant Species
• Metabolite list (11)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Tordylium apulum
Genus	Tordylium
Family	Apiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Tordylium apulum
Linked NCBI taxonomy ID	489417
Linked level	species

Family

Family in NCBI taxonomy	Apiaceae
ID	4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (11)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005548	Narcissin / Isorhamnetin 3-O-rutinoside	CHEMBL84174 CHEMBL258394 CHEMBL1711509 CHEMBL2165403	C031062	7 / 1 / 2		No. 1	No. 15
C00013882	Quercetin 3-(3'',4''-diacetylrhamnosyl)-(1->6)-glucoside					No. 1	No. 15
C00005413	Rutin / Birutan / 3-Rutinosylquercetin / Quercetin 3-O-rutinoside / (+)-Quercetin 3-O-rutinoside / Quercetin 3-O-beta-rutinoside / (+)-Quercetin 3-O-beta-rutinoside / 3,3',4',5,7-Pentahydroxyflavone 3-rutinoside / Quercetin 3-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside	CHEMBL32579 CHEMBL310754 CHEMBL182108 CHEMBL226335 CHEMBL502782 CHEMBL1436093 CHEMBL1532989	D012431	25 / 18 / 16	29 / 8	No. 1	No. 15
C00005169	Nicotiflorin / Nicotifloroside / Kaempferol 3-O-rutinoside / Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside / (-)-Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside	CHEMBL431610 CHEMBL79790 CHEMBL255020 CHEMBL501550 CHEMBL498879 CHEMBL1419228 CHEMBL1875691		22 / 10 / 12		No. 1	No. 15
C00000583	Isopimpinellin	CHEMBL140796	C015304	9 / 3 / 4	2 / 0	No. 606	No. 25
C00002503	Umbelliferon / Umbelliferone / 7-Hydroxycoumarin	CHEMBL51628	C031477	39 / 33 / 32	9 / 0	No. 1030	No. 25
C00000576	Xanthotoxin	CHEMBL416	D008730	104 / 55 / 45	22 / 18	No. 1282	No. 25
C00037321	Isobergapten	CHEMBL141690		8 / 5 / 4		No. 1282	No. 25
C00035183	Columbianetin acetate		C076302			No. 1319	No. 25
C00044128	Cnidiadin					No. 1319	No. 25
C00029297	Columbianetin / (+)-Columbianetin	CHEMBL201152		7 / 12 / 8		No. 1336	No. 25

Human Protein / Gene in interactions

165 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000576 C00000583 C00005413 C00005548 C00037321	0 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000583 C00002503 C00005413 C00029297 C00037321	0 / 0
P56817	Beta-secretase 1	A1A	C00000576 C00000583 C00002503 C00029297	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002503 C00005169 C00005413 C00029297	1 / 1
O75496	Geminin	Unclassified protein	C00002503 C00005169 C00005548 C00037321	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000583 C00005169 C00005413	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00002503 C00005169 C00005413	1 / 1
P06746	DNA polymerase beta	Enzyme	C00000583 C00005169 C00005413	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000583 C00002503 C00029297	2 / 2
P00352	Retinal dehydrogenase 1	Enzyme	C00002503 C00029297 C00037321	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000576 C00002503 C00005413	0 / 3
P22303	Acetylcholinesterase	Hydrolase	C00000576 C00002503 C00005413	1 / 0
P03372	Estrogen receptor	NR3A1	C00000576 C00005413 C00005548	1 / 1
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00000576 C00000583	1 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002503 C00005413	3 / 3
Q9UNA4	DNA polymerase iota	Enzyme	C00005169 C00005548	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00005413 C00037321	4 / 3
P28482	Mitogen-activated protein kinase 1	Erk	C00000576 C00005413	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002503 C00005169	1 / 1
P29466	Caspase-1	C14	C00000576 C00002503	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00002503 C00005413	4 / 2
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00005413 C00037321	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000576 C00002503	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00000576 C00029297	7 / 3
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00000576 C00005548	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000576 C00005413	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00005169 C00005413	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00005413 C00037321	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00000576 C00002503	1 / 2
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00000583 C00002503	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002503 C00005169	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002503 C00005169	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000576 C00005169	2 / 3
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00005169 C00005413	1 / 0
P07237	Protein disulfide-isomerase	Enzyme	C00005169 C00005548	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000576 C00005413	0 / 0
P27487	Dipeptidyl peptidase 4	S9B	C00005413	0 / 1
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000576	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000576	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000576	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000576	0 / 1
P23443	Ribosomal protein S6 kinase beta-1	p70	C00000576	0 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000576	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000576	1 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000576	1 / 8
P11388	DNA topoisomerase 2-alpha	Isomerase	C00005413	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000576	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00000576	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000576	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000576	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000576	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000576	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000576	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000576	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000576	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000576	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000576	1 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00000576	0 / 0
P28845	Corticosteroid 11-beta-dehydrogenase isozyme 1	Enzyme	C00002503	1 / 1
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00029297	2 / 2
O43570	Carbonic anhydrase 12	Lyase	C00002503	1 / 2
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000576	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000576	1 / 1
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000576	0 / 1
P16473	Thyrotropin receptor	Glycohormone receptor	C00000576	3 / 2
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00002503	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000576	0 / 0
P20813	Cytochrome P450 2B6	Cytochrome P450 2B6	C00000576	1 / 0
P18405	3-oxo-5-alpha-steroid 4-dehydrogenase 1	Oxidoreductase	C00002503	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000576	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000576	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000576	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000576	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000576	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000576	0 / 0
P15121	Aldose reductase	Enzyme	C00002503	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00000576	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000576	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000576	1 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002503	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000576	0 / 0
P08311	Cathepsin G	S1A	C00000576	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000576	1 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00005169	0 / 0
P03956	Interstitial collagenase	M10A	C00000576	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000576	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000576	2 / 2
Q9Y253	DNA polymerase eta	Enzyme	C00005169	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00005169	0 / 0
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00002503	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00000576	1 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00000576	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00000576	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000576	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000576	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000576	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000576	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000576	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000576	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000576	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000576	0 / 0
P06276	Cholinesterase	Hydrolase	C00005413	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000576	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000576	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000576	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00002503	1 / 1
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000576	1 / 0
P04062	Glucosylceramidase	Enzyme	C00002503	6 / 4
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000576	2 / 1
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000576	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000576	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00002503	0 / 1
Q16539	Mitogen-activated protein kinase 14	p38	C00000576	0 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00005413	2 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000576	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000576	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00005548	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00002503	0 / 0
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00002503	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000576	0 / 0
P08246	Neutrophil elastase	S1A	C00000576	2 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000576	1 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000576	2 / 2
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000576	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000576	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000576	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000576	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000576	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000576	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000576	0 / 0
Q00796	Sorbitol dehydrogenase	Enzyme	C00002503	0 / 0
P55210	Caspase-7	C14	C00002503	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000576	1 / 1
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000576	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000576	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00002503	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00005169	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00000576	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00002503	5 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00005169	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000583	0 / 0
P10275	Androgen receptor	NR3C4	C00000576	3 / 4
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000576	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00000576	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000576	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00000576	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000576	0 / 0
P48147	Prolyl endopeptidase	S9A	C00005413	0 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00002503	1 / 1
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00000576	1 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00002503	3 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00005169	0 / 0
Q09470	Potassium voltage-gated channel subfamily A member 1	KCNA, Kv1.x (Shaker)	C00000576	1 / 1
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002503	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00037321	1 / 0
O00255	Menin	Unclassified protein	C00002503	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002503	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00005169	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00005169	1 / 4
P33527	Multidrug resistance-associated protein 1	drugs	C00005413	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00005169	2 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000576	1 / 0

52 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
581	BAX, BCL2L4	BCL2-associated X protein	C00000576 C00002503 C00005413
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000576 C00002503 C00005413
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00000583 C00005413
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000576 C00005413
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000576 C00005413
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000576 C00000583
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000576 C00005413
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00000576 C00002503
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00000576
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00002503
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00002503
8553	BHLHE40, BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14	basic helix-loop-helix family, member e40	C00000576
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00000576
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002503
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000576
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000576
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00000576
8824	CES2, CE-2, CES2A1, PCE-2, iCE	carboxylesterase 2 (EC:3.1.1.1 3.1.1.84 3.1.1.56)	C00000576
8574	AKR7A2, AFAR, AFAR1, AFB1-AR1, AKR7	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (EC:1.1.1.n11)	C00002503
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00000576
1553	CYP2A13, CPAD, CYP2A, CYPIIA13	cytochrome P450, family 2, subfamily A, polypeptide 13 (EC:1.14.14.1)	C00000576
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000576
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00000576
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000576
3034	HAL, HIS, HSTD	histidine ammonia-lyase (EC:4.3.1.3)	C00000576
3355109			C00000576
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00002503
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00002503
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000576
177	AGER, RAGE	advanced glycosylation end product-specific receptor	C00005413
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00005413
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00005413
847	CAT	catalase (EC:1.11.1.6)	C00005413
873	CBR1, CBR, SDR21C1, hCBR1	carbonyl reductase 1 (EC:1.1.1.189 1.1.1.197 1.1.1.184)	C00005413
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00005413
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00005413
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00005413
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00005413
3458	IFNG, IFG, IFI	interferon, gamma	C00005413
3480	IGF1R, CD221, IGFIR, IGFR, JTK13	insulin-like growth factor 1 receptor (EC:2.7.10.1)	C00005413
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00005413
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00005413
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00005413
3667	IRS1, HIRS-1	insulin receptor substrate 1	C00005413
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00005413
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00005413
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00005413
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00005413
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00005413
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00005413
7039	TGFA, TFGA	transforming growth factor, alpha	C00005413
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00005413

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