Henriettella fascicularis

• Index
• Plant Species
• Metabolite list (7)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Henriettella fascicularis
Genus	Henriettella
Family	Melastomataceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Henriettea fascicularis
Linked NCBI taxonomy ID	883786
Linked level	species

Family

Family in NCBI taxonomy	Melastomataceae
ID	39998

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (7)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00019011	5,7,4'-Trihydroxy-6,8-dimethylisoflavone	CHEMBL512579		2 / 1 / 1		No. 3	No. 15
C00003741	Betulinic acid	CHEMBL269277 CHEMBL71690 CHEMBL519059 CHEMBL1318530 CHEMBL2005635	C002070	34 / 17 / 14	10 / 2	No. 23	No. 51
C00000587	(-)-Pinoresinol	CHEMBL267963 CHEMBL487611 CHEMBL460862		7 / 5 / 6		No. 38	No. 21
C00003672	Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00001233	Palmitic acid	CHEMBL82293	D019308	16 / 8 / 8	35 / 1	No. 184	No. 68
C00037418	Lichexanthone	CHEMBL470650				No. 493	No. 65
C00019012	(2E,6S)- 6-[(1R,3aS,5Z,9R,10Z,12aR)-1,2,3,3a,4,7,8,9,12,12a-Decahydro-9-hydroxy-3a,6,10-trimethyl-1-cyclopentacycloundecenyl]-2-methyl-2-heptenoic acid					No. 5815

Human Protein / Gene in interactions

60 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P03372	Estrogen receptor	NR3A1	C00001233 C00003672 C00019011	1 / 1
Q96RI1	Bile acid receptor	NR1H4	C00001233 C00003741	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003672 C00003741	0 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003672 C00003741	2 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003672 C00003741	1 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003672 C00003741	1 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003672 C00003741	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00000587 C00001233	0 / 0
P06746	DNA polymerase beta	Enzyme	C00003672 C00003741	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003672 C00003741	0 / 0
O75496	Geminin	Unclassified protein	C00001233 C00003741	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00001233 C00003741	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003672 C00003741	0 / 1
P08183	Multidrug resistance protein 1	drug	C00001233 C00003672	1 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00001233 C00003672	0 / 0
Q04206	Transcription factor p65	Transcription Factor	C00003741	0 / 0
Q02156	Protein kinase C epsilon type	Eta	C00003741	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00003741	11 / 10
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003741	0 / 0
P15559	NAD(P)H dehydrogenase [quinone] 1	Enzyme	C00003741	0 / 0
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00003741	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003741	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00003741	0 / 0
P08151	Zinc finger protein GLI1	Unclassified protein	C00003741	0 / 0
P05413	Fatty acid-binding protein, heart	Other cytosolic protein	C00001233	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00019011	0 / 1
P15121	Aldose reductase	Enzyme	C00003741	0 / 0
P12104	Fatty acid-binding protein, intestinal	Other cytosolic protein	C00001233	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000587	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00003741	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00003672	3 / 2
Q9Y253	DNA polymerase eta	Enzyme	C00003741	1 / 1
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00003741	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00001233	0 / 0
P00734	Prothrombin	S1A	C00003672	4 / 2
P04150	Glucocorticoid receptor	NR3C1	C00001233	0 / 1
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00001233	2 / 2
P14679	Tyrosinase	Oxidoreductase	C00003672	4 / 2
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00000587	5 / 3
P15090	Fatty acid-binding protein, adipocyte	Other cytosolic protein	C00001233	0 / 0
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00003741	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000587	0 / 3
P55055	Oxysterols receptor LXR-beta	NR1H3	C00003741	0 / 0
Q01469	Fatty acid-binding protein, epidermal	Other cytosolic protein	C00001233	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00000587	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000587	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00003741	0 / 0
P05771	Protein kinase C beta type	Alpha	C00003741	0 / 0
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00003741	0 / 0
O60603	Toll-like receptor 2	Membrane receptor	C00001233	1 / 1
P10275	Androgen receptor	NR3C4	C00001233	3 / 4
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00003672	0 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00003672	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00003741	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003672	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00003741	1 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00003741	0 / 0
Q9UBT2	SUMO-activating enzyme subunit 2	Enzyme	C00003741	0 / 0
Q9UBE0	SUMO-activating enzyme subunit 1	Unclassified protein	C00003741	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00000587	0 / 0

41 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00001233 C00003741
581	BAX, BCL2L4	BCL2-associated X protein	C00001233 C00003741
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00001233 C00003741
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00001233 C00003741
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001233
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003741
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00003741
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00003741
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00003741
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00003741
9619	ABCG1, ABC8, WHITE1	ATP-binding cassette, sub-family G (WHITE), member 1	C00001233
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00001233
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00001233
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00001233
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00001233
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00001233
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00001233
3034	HAL, HIS, HSTD	histidine ammonia-lyase (EC:4.3.1.3)	C00001233
57817	HAMP, HEPC, HFE2B, LEAP1, PLTR	hepcidin antimicrobial peptide	C00001233
3481	IGF2, C11orf43, IGF-II, PP9974	insulin-like growth factor 2 (somatomedin A)	C00001233
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00003741
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00001233
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00001233
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00001233
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00001233
4493	MT1E, MT1, MTD	metallothionein 1E	C00001233
4494	MT1F, MT1	metallothionein 1F	C00001233
4496	MT1H, MT-0, MT-1H, MT-IH, MT1	metallothionein 1H	C00001233
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00001233
4502	MT2A, MT2	metallothionein 2A	C00001233
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00001233
3651	PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1	pancreatic and duodenal homeobox 1	C00001233
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00001233
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00001233
29893	PSMC3IP, GT198, HOP2, HUMGT198A, ODG3, TBPIP	PSMC3 interacting protein	C00001233
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00001233
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00001233
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00001233
23216	TBC1D1, TBC, TBC1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	C00001233
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00001233
7351	UCP2, BMIQ4, SLC25A8, UCPH	uncoupling protein 2 (mitochondrial, proton carrier)	C00001233

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions