| Organism name | Sequoia sempervirens | 
|---|---|
| Genus | Sequoia | 
| Family | Taxodiaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Sequoia sempervirens | 
|---|---|
| Linked NCBI taxonomy ID | 28980 | 
| Linked level | species | 
| Family in NCBI taxonomy | Cupressaceae | 
|---|---|
| ID | 3367 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | Spermatophyta | 
|---|---|
| ID | 58024 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00006487   | Sequoiaflavone | CHEMBL255493 | 1 / 0 / 0 | No. 34 | No. 18 |   | ||
| C00001172   | Sequoyitol / 5-O-Methyl-myo-inositol | CHEMBL171890 CHEMBL501109 CHEMBL493737 CHEMBL460057 | 2 / 1 / 1 | No. 795 |   | |||
| C00002665   | Phloroglucinol | CHEMBL473159 | D010696 | 3 / 4 / 2 | 8 / 2 | No. 1590 | No. 82 |   | 
| C00000597   | Sequirin B / (-)-Hydroxysugiresinol | No. 2651 | No. 24 |   | ||||
| C00046399   | Sequoiatone E / (+)-Sequoiatone E | CHEMBL495444 | No. 2817 |   | ||||
| C00046398   | Sequoiatone D / (+)-Sequoiatone D | CHEMBL495443 | No. 2817 |   | ||||
| C00046397   | Sequoiatone C / (+)-Sequoiatone C | CHEMBL495442 | No. 2817 |   | ||||
| C00046400   | Sequoiatone F / (+)-Sequoiatone F | No. 5094 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P56817 | Beta-secretase 1 | A1A | C00002665 C00006487 | 0 / 0 | 
| P14679 | Tyrosinase | Oxidoreductase | C00002665 | 4 / 2 | 
| Q9Y253 | DNA polymerase eta | Enzyme | C00001172 | 1 / 1 | 
| O75496 | Geminin | Unclassified protein | C00001172 | 0 / 0 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00002665 | 0 / 0 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) | C00002665 | 
| 581 | BAX, BCL2L4 | BCL2-associated X protein | C00002665 | 
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 | C00002665 | 
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | C00002665 | 
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | C00002665 | 
| 9518 | GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB | growth differentiation factor 15 | C00002665 | 
| 2932 | GSK3B | glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) | C00002665 | 
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | C00002665 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #103470 | Albinism, ocular, with sensorineural deafness | P14679 | 
| #203100 | Albinism, oculocutaneous, type ia; oca1a | P14679 | 
| #606952 | Albinism, oculocutaneous, type ib; oca1b | P14679 | 
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 | P14679 | 
| #278750 | Xeroderma pigmentosum, variant type; xpv | Q9Y253 |