Species

KNApSAcK Entry

Organism name Ceratiola ericoides
Genus Ceratiola
Family Ericaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ceratiola ericoides
Linked NCBI taxonomy ID 13411
Linked level species

Family

Family in NCBI taxonomy Ericaceae
ID 4345

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00008168 External link 512 Desmethoxymatteucinol
CHEMBL53439
5 / 1 / 4 No. 25 No. 14
C00008126 External link 512 7-Hydroxyflavanone
CHEMBL97542
CHEMBL402744
C059353
9 / 18 / 45 1 / 0 No. 25 No. 14
C00008166 External link 512 Cryptostrobin
CHEMBL1269161
No. 25 No. 14
C00007997 External link 512 Myrigalon B
No. 90 No. 13
C00007922 External link 512 2',4'-Dihydroxydihydrochalcone
No. 90 No. 13
C00007998 External link 512 Angoletin
CHEMBL452234
C105002
No. 90 No. 13
C00006920 External link 512 2',4'-Dihydroxychalcone
CHEMBL105310
19 / 25 / 22 No. 92 No. 13
C00007981 External link 512 Ceratiolin
No. 8045

Human Protein / Gene in interactions

33 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P33527 Multidrug resistance-associated protein 1 drugs C00006920 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00008126 7 / 37
Q16637 Survival motor neuron protein Unclassified protein C00006920 4 / 1
Q99700 Ataxin-2 Unclassified protein C00008168 1 / 1
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00008168 0 / 3
P10828 Thyroid hormone receptor beta NR1A2 C00006920 3 / 1
P05091 Aldehyde dehydrogenase, mitochondrial Oxidoreductase C00008126 1 / 1
P08183 Multidrug resistance protein 1 drug C00006920 1 / 0
P11473 Vitamin D3 receptor NR1I1 C00006920 2 / 3
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00008168 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00006920 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00008126 4 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00008126 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00008168 0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00006920 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00006920 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00008126 0 / 1
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00008126 2 / 2
P28482 Mitogen-activated protein kinase 1 Erk C00006920 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00006920 3 / 3
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00006920 2 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00006920 2 / 2
P16050 Arachidonate 15-lipoxygenase Enzyme C00006920 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00006920 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00008168 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00006920 4 / 3
P10275 Androgen receptor NR3C4 C00008126 3 / 4
B2RXH2 Lysine-specific demethylase 4E Enzyme C00006920 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00006920 1 / 1
O00255 Menin Unclassified protein C00006920 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00006920 1 / 2
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00008126 0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00008126 1 / 1

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00008126

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (44)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#610251 Alcohol sensitivity, acute P05091
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#614490 Blood group, junior system; jr Q9UNQ0
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#119900 Digital clubbing, isolated congenital P15428
#133239 Esophageal cancer P04637
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#612244 Inflammatory bowel disease 13; ibd13 P08183
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#211980 Lung cancer P04637
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (65)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H01071 Acute alcohol sensitivity P05091 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00548 Brunner syndrome P21397 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)