| Organism name | Ceratiola ericoides | 
|---|---|
| Genus | Ceratiola | 
| Family | Ericaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Ceratiola ericoides | 
|---|---|
| Linked NCBI taxonomy ID | 13411 | 
| Linked level | species | 
| Family in NCBI taxonomy | Ericaceae | 
|---|---|
| ID | 4345 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00008168   | Desmethoxymatteucinol | CHEMBL53439 | 5 / 1 / 4 | No. 25 | No. 14 |   | ||
| C00008126   | 7-Hydroxyflavanone | CHEMBL97542 CHEMBL402744 | C059353 | 9 / 18 / 45 | 1 / 0 | No. 25 | No. 14 |   | 
| C00008166   | Cryptostrobin | CHEMBL1269161 | No. 25 | No. 14 |   | |||
| C00007997   | Myrigalon B | No. 90 | No. 13 |   | ||||
| C00007922   | 2',4'-Dihydroxydihydrochalcone | No. 90 | No. 13 |   | ||||
| C00007998   | Angoletin | CHEMBL452234 | C105002 | No. 90 | No. 13 |   | ||
| C00006920   | 2',4'-Dihydroxychalcone | CHEMBL105310 | 19 / 25 / 22 | No. 92 | No. 13 |   | ||
| C00007981   | Ceratiolin | No. 8045 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00006920 | 0 / 0 | 
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00008126 | 7 / 37 | 
| Q16637 | Survival motor neuron protein | Unclassified protein | C00006920 | 4 / 1 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00008168 | 1 / 1 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00008168 | 0 / 3 | 
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00006920 | 3 / 1 | 
| P05091 | Aldehyde dehydrogenase, mitochondrial | Oxidoreductase | C00008126 | 1 / 1 | 
| P08183 | Multidrug resistance protein 1 | drug | C00006920 | 1 / 0 | 
| P11473 | Vitamin D3 receptor | NR1I1 | C00006920 | 2 / 3 | 
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00008168 | 0 / 0 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00006920 | 0 / 0 | 
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00008126 | 4 / 2 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00008126 | 0 / 0 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00008168 | 0 / 0 | 
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00006920 | 0 / 0 | 
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00006920 | 0 / 0 | 
| P04150 | Glucocorticoid receptor | NR3C1 | C00008126 | 0 / 1 | 
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00008126 | 2 / 2 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00006920 | 0 / 0 | 
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00006920 | 3 / 3 | 
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00006920 | 2 / 0 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00006920 | 2 / 2 | 
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00006920 | 0 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00006920 | 0 / 1 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00008168 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00006920 | 4 / 3 | 
| P10275 | Androgen receptor | NR3C4 | C00008126 | 3 / 4 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00006920 | 0 / 0 | 
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00006920 | 1 / 1 | 
| O00255 | Menin | Unclassified protein | C00006920 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00006920 | 1 / 2 | 
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00008126 | 0 / 0 | 
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00008126 | 1 / 1 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 1588 | CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM | cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | C00008126 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency | Q99714 | 
| #202300 | Adrenocortical carcinoma, hereditary; adcc | P04637 | 
| #610251 | Alcohol sensitivity, acute | P05091 | 
| #300068 | Androgen insensitivity syndrome; ais | P10275 | 
| #312300 | Androgen insensitivity, partial; pais | P10275 | 
| #613546 | Aromatase deficiency | P11511 | 
| #139300 | Aromatase excess syndrome; aexs | P11511 | 
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 | P04637 | 
| #614490 | Blood group, junior system; jr | Q9UNQ0 | 
| #114480 | Breast cancer | P38398 | 
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 | P38398 | 
| #300615 | Brunner syndrome | P21397 | 
| #119900 | Digital clubbing, isolated congenital | P15428 | 
| #133239 | Esophageal cancer | P04637 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | P15428 | 
| #612244 | Inflammatory bowel disease 13; ibd13 | P08183 | 
| #151623 | Li-fraumeni syndrome 1; lfs1 | P04637 | 
| #211980 | Lung cancer | P04637 | 
| #300705 | Mental retardation, x-linked 17; mrx17 | Q99714 | 
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 | Q99714 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #607948 | Mycobacterium tuberculosis, susceptibility to | P11473 | 
| #167000 | Ovarian cancer | P38398 | 
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 | P38398 | 
| #260500 | Papilloma of choroid plexus; cpp | P04637 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 | P10275 | 
| #253300 | Spinal muscular atrophy, type i; sma1 | Q16637 | 
| #253550 | Spinal muscular atrophy, type ii; sma2 | Q16637 | 
| #253400 | Spinal muscular atrophy, type iii; sma3 | Q16637 | 
| #271150 | Spinal muscular atrophy, type iv; sma4 | Q16637 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 | Q9NUW8 | 
| #275355 | Squamous cell carcinoma, head and neck; hnscc | P04637 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth | P10828 | 
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth | P10828 | 
| #145650 | Thyroid hormone resistance, selective pituitary; prth | P10828 | 
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 | Q9UNQ0 | 
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | P11473 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) P04637 (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) | P04150
                            (related) P11511 (related) | 
| H00004 | Chronic myeloid leukemia (CML) | P04637
                            (related) | 
| H00005 | Chronic lymphocytic leukemia (CLL) | P04637
                            (related) | 
| H00006 | Hairy-cell leukemia | P04637
                            (related) | 
| H00008 | Burkitt lymphoma | P04637
                            (related) | 
| H00009 | Adult T-cell leukemia | P04637
                            (related) | 
| H00010 | Multiple myeloma | P04637
                            (related) | 
| H00013 | Small cell lung cancer | P04637
                            (related) | 
| H00014 | Non-small cell lung cancer | P04637
                            (related) | 
| H00015 | Malignant pleural mesothelioma | P04637
                            (related) | 
| H00016 | Oral cancer | P04637
                            (related) P04637 (marker) | 
| H00017 | Esophageal cancer | P04637
                            (related) P04637 (marker) P35354 (related) | 
| H00018 | Gastric cancer | P04637
                            (related) | 
| H00019 | Pancreatic cancer | P04637
                            (related) P04637 (marker) | 
| H00020 | Colorectal cancer | P04637
                            (related) P04637 (marker) | 
| H00022 | Bladder cancer | P04637
                            (related) | 
| H00025 | Penile cancer | P04637
                            (related) P04637 (marker) P35354 (related) | 
| H00026 | Endometrial Cancer | P04637
                            (related) | 
| H00027 | Ovarian cancer | P04637
                            (related) P38398 (related) | 
| H00028 | Choriocarcinoma | P04637
                            (related) | 
| H00029 | Vulvar cancer | P04637
                            (related) | 
| H00031 | Breast cancer | P04637
                            (related) P38398 (related) | 
| H00032 | Thyroid cancer | P04637
                            (related) | 
| H00036 | Osteosarcoma | P04637
                            (related) P08684 (marker) | 
| H00038 | Malignant melanoma | P04637
                            (related) | 
| H00039 | Basal cell carcinoma | P04637
                            (related) | 
| H00040 | Squamous cell carcinoma | P04637
                            (related) | 
| H00041 | Kaposi's sarcoma | P04637
                            (related) | 
| H00042 | Glioma | P04637
                            (related) P04637 (marker) | 
| H00044 | Cancer of the anal canal | P04637
                            (related) | 
| H00046 | Cholangiocarcinoma | P04637
                            (related) P35354 (related) | 
| H00047 | Gallbladder cancer | P04637
                            (related) | 
| H00048 | Hepatocellular carcinoma | P04637
                            (related) | 
| H00055 | Laryngeal cancer | P04637
                            (related) P04637 (marker) | 
| H00881 | Li-Fraumeni syndrome | P04637
                            (related) | 
| H01007 | Choroid plexus papilloma | P04637
                            (related) | 
| H00021 | Renal cell carcinoma | P04637
                            (marker) | 
| H01071 | Acute alcohol sensitivity | P05091
                            (related) | 
| H00024 | Prostate cancer | P10275
                            (related) | 
| H00062 | Spinal and bulbar muscular atrophy (SBMA) | P10275
                            (related) | 
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) | P10275
                            (related) | 
| H00609 | 46,XY disorders of sex development (Other) | P10275
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00249 | Thyroid hormone resistance syndrome | P10828
                            (related) | 
| H00342 | Tuberculosis | P11473
                            (related) | 
| H00784 | Localized autosomal recessive hypotrichosis | P11473
                            (related) | 
| H01143 | Vitamin D-dependent rickets | P11473
                            (related) | 
| H00794 | Aromatase excess syndrome | P11511
                            (related) | 
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | P15428
                            (related) | 
| H01246 | Isolated congenital nail clubbing (ICNC) | P15428
                            (related) | 
| H00548 | Brunner syndrome | P21397
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00455 | Spinal muscular atrophy (SMA) | Q16637
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) Q9NUW8 (related) | 
| H00480 | Non-syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00658 | Syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency | Q99714
                            (related) |