Species

KNApSAcK Entry

Organism name Dracaena cochinchinensis
Genus Dracaena
Family Dracaenaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Dracaena cochinchinensis
Linked NCBI taxonomy ID 593754
Linked level species

Family

Family in NCBI taxonomy Asparagaceae
ID 40552

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (14)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00014604 External link 512 4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone
CHEMBL400283
No. 90 No. 13
C00014597 External link 512 4'-Hydroxy-2,6-dimethoxydihydrochalcone
No. 90 No. 13
C00006927 External link 512 Isoliquiritigenin 2'-methy ether
/ 4,4'-Dihydroxy-2'-methoxychalcone
CHEMBL253777
7 / 20 / 19 No. 92 No. 13
C00038096 External link 512 (2S)-4',5-Dihydroxy-7-methoxy-8-methylflavan
CHEMBL253562
No. 179 No. 15
C00040540 External link 512 trans-3,5-Dihydroxy-4'-methoxystilbene
CHEMBL291501
CHEMBL313687
6 / 13 / 13 No. 295 No. 13
C00038095 External link 512 (2R)-8-Methylsocotrin-4'-ol
CHEMBL254647
2 / 4 / 3 No. 435
C00014639 External link 512 Cochinchinenin
/ 3-[2,4-Dihydroxy-5-[3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)propyl]phenyl]-1-(4-hydroxyphenyl)-1-propanone
No. 435
C00038812 External link 512 Cochinchinenene A
/ (+)-Cochinchinenene A
CHEMBL254229
2 / 4 / 3 No. 435
C00038813 External link 512 Cochinchinenene B
/ (+)-Cochinchinenene B
CHEMBL399481
2 / 4 / 3 No. 435
C00038817 External link 512 Cochinchinenin C
/ (+)-Cochinchinenin C
CHEMBL254649
2 / 4 / 3 No. 435
C00038815 External link 512 Cochinchinenene D
/ (+)-Cochinchinenene D
CHEMBL254440
2 / 4 / 3 No. 435
C00038816 External link 512 Cochinchinenin B
/ (+)-Cochinchinenin B
CHEMBL254648
2 / 4 / 3 No. 435
C00038814 External link 512 Cochinchinenene C
/ (+)-Cochinchinenene C
CHEMBL254439
2 / 4 / 3 No. 435
C00014596 External link 512 2,4,4'-Trihydroxydihydrochalcone
CHEMBL253564
No. 548 No. 13

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P27487 Dipeptidyl peptidase 4 S9B C00038095 C00038812 C00038813 C00038814 C00038815 C00038816 C00038817 0 / 1
P00734 Prothrombin S1A C00038095 C00038812 C00038813 C00038814 C00038815 C00038816 C00038817 4 / 2
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00006927 0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00006927 1 / 8
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00040540 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00040540 0 / 3
P21802 Fibroblast growth factor receptor 2 TK tyrosine-protein kinase TLK subfamily C00006927 9 / 3
P02545 Prelamin-A/C Unclassified protein C00040540 11 / 10
P35968 Vascular endothelial growth factor receptor 2 Vegfr C00006927 1 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00040540 2 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00006927 2 / 3
P11362 Fibroblast growth factor receptor 1 Fgfr C00006927 4 / 5
O43451 Maltase-glucoamylase, intestinal Hydrolase C00040540 0 / 0
P10721 Mast/stem cell growth factor receptor Kit Pdgfr C00006927 4 / 3
B2RXH2 Lysine-specific demethylase 4E Enzyme C00040540 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (37)

OMIM preferred title UniProt
#207410 Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 P21802
#101200 Apert syndrome P21802
#123790 Beare-stevenson cutis gyrata syndrome; bstvs P21802
#614592 Bent bone dysplasia syndrome; bbds P21802
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P18054
#123500 Crouzon syndrome P21802
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P18054
#606764 Gastrointestinal stromal tumor; gist P10721
#610140 Heart-hand syndrome, slovenian type P02545
#602089 Hemangioma, capillary infantile P35968
#114550 Hepatocellular carcinoma P08581
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#147950 Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 P11362
#123150 Jackson-weiss syndrome; jws P21802
#149730 Lacrimoauriculodentodigital syndrome; ladd P21802
#601626 Leukemia, acute myeloid; aml P10721
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#211980 Lung cancer P00533
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#166250 Osteoglophonic dysplasia; ogd P11362
#101600 Pfeiffer syndrome P11362
P21802
#172800 Piebald trait; pbt P10721
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#275210 Restrictive dermopathy, lethal P02545
#609579 Scaphocephaly, maxillary retrusion, and mental retardation P21802
#601367 Stroke, ischemic P00734
#273300 Testicular germ cell tumor; tgct P10721
#188050 Thrombophilia due to thrombin defect; thph1 P00734
#190440 Trigonocephaly 1; trigno1 P11362

KEGG DISEASE (33)

KEGG name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P08581 (related)
P21802 (related)
H00022 Bladder cancer P00533 (related)
H00028 Choriocarcinoma P00533 (related)
H00030 Cervical cancer P00533 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00021 Renal cell carcinoma P08581 (related)
H00046 Cholangiocarcinoma P08581 (related)
P35354 (related)
H00003 Acute myeloid leukemia (AML) P10721 (related)
P10721 (marker)
H00170 Piebaldism P10721 (related)
H00023 Testicular cancer P10721 (marker)
H00255 Hypogonadotropic hypogonadism P11362 (related)
H00443 Osteoglophonic dysplasia (OD) P11362 (related)
H00458 Craniosynostosis P11362 (related)
P21802 (related)
H00516 Isolated orofacial clefts P11362 (related)
H01207 Trigonocephaly P11362 (related)
H00642 Lacrimo-auriculo-dento-digital syndrome (LADD) P21802 (related)
H00032 Thyroid cancer P27487 (marker)
H00025 Penile cancer P35354 (related)