Piper longum

• Index
• Plant Species
• Metabolite list (10)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Piper longum
Genus	Piper
Family	Piperaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Piper longum
Linked NCBI taxonomy ID	49511
Linked level	species

Family

Family in NCBI taxonomy	Piperaceae
ID	16739

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Magnoliophyta
ID	3398

Metabolite list (10)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00007195	(+)-Fargesin	CHEMBL462822	C058339			No. 38	No. 21
C00027470	Piperolactam A	CHEMBL387864	C457227			No. 125
C00000601	(+)-Sesamin	CHEMBL43469 CHEMBL252915 CHEMBL1572261 CHEMBL1591714 CHEMBL1708854 CHEMBL1904496 CHEMBL1968861	C054125	20 / 24 / 15	0 / 5	No. 621	No. 21
C00034654	Retrofractamide A					No. 638
C00030436	Guineensine					No. 638
C00002663	2-Phenylethanol / Phenethyl alcohol / Phenylethyl alcohol / beta-Phenethyl alcohol	CHEMBL448500	D010626	2 / 1 / 1		No. 885
C00002066	Piplartine / Piperlongumine	CHEMBL465843 CHEMBL1456697		28 / 44 / 65		No. 1640	No. 1
C00028813	Pellitorine		C008778			No. 1863
C00003204	l-Zingiberene / (-)-Zingiberene / alpha-Zingiberene	CHEMBL479020				No. 2380	No. 38
C00002065	Piperine / Bioperine / 1-Piperoylpiperidine	CHEMBL43185 CHEMBL1395862		32 / 47 / 64		No. 4209	No. 1

Human Protein / Gene in interactions

47 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000601 C00002065 C00002066	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000601 C00002065 C00002066	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00000601 C00002065 C00002066	4 / 1
O75496	Geminin	Unclassified protein	C00000601 C00002066 C00002663	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000601 C00002065 C00002066	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000601 C00002065 C00002066	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000601 C00002065 C00002066	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00000601 C00002065 C00002066	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000601 C00002065 C00002066	0 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00000601 C00002065 C00002066	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000601 C00002066	4 / 3
P11473	Vitamin D3 receptor	NR1I1	C00000601 C00002066	2 / 3
P02545	Prelamin-A/C	Unclassified protein	C00002065 C00002066	11 / 10
P00352	Retinal dehydrogenase 1	Enzyme	C00002065 C00002066	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002065 C00002066	1 / 1
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000601 C00002065	2 / 2
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000601 C00002066	2 / 0
Q99700	Ataxin-2	Unclassified protein	C00002065 C00002066	1 / 1
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002065 C00002066	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002065 C00002066	3 / 3
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00000601 C00002066	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002065 C00002066	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002065 C00002066	7 / 37
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000601 C00002065	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00000601 C00002066	1 / 1
P04150	Glucocorticoid receptor	NR3C1	C00002065	0 / 1
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00002065	5 / 3
Q8NER1	Transient receptor potential cation channel subfamily V member 1	TRPV (Vanilloid)	C00002065	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00002065	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000601	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00000601	7 / 3
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00002065	4 / 2
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00002066	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00002065	2 / 2
O75030	Microphthalmia-associated transcription factor	Unclassified protein	C00002066	4 / 4
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00000601	0 / 0
P08183	Multidrug resistance protein 1	drug	C00002065	1 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00002065	1 / 1
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002065	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00002065	3 / 2
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00002065	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00002065	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002065	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002663	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002066	1 / 0
Q06710	Paired box protein Pax-8	Unclassified protein	C00002066	1 / 2
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00002066	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions