Species

KNApSAcK Entry

Organism name Hibiscus cannabinus
Genus Hibiscus
Family Malvaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Hibiscus cannabinus
Linked NCBI taxonomy ID 229543
Linked level species

Family

Family in NCBI taxonomy Malvaceae
ID 3629

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (14)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005189 External link 512 Kaempferitrin
/ Kaempferol 3,7-di-O-rhamnoside
/ Kaempferol 3,7-di-O-alpha-rhamnopyranoside
CHEMBL251766
C042728
2 / 5 / 5 No. 1 No. 15
C00005793 External link 512 Hibiscetin 3-glucoside
No. 2 No. 15
C00007190 External link 512 (+)-Pinoresinol
CHEMBL267963
CHEMBL487611
CHEMBL460862
C103298
7 / 5 / 6 No. 38 No. 21
C00002631 External link 512 (+)-Lirioresinol B
/ (+)-Syringaresinol
CHEMBL361362
CHEMBL402653
C042192
1 / 0 / 0 No. 38 No. 21
C00000659 External link 512 Medioresinol
/ (+)-Medioresinol
CHEMBL376507
CHEMBL513023
2 / 1 / 1 No. 38 No. 21
C00035142 External link 512 N-trans-Feruloyl tyramine
CHEMBL206555
CHEMBL451720
1 / 4 / 2 No. 499
C00000602 External link 512 (+)-Lariciresinol
CHEMBL518421
2 / 1 / 1 No. 700 No. 21
C00037914 External link 512 threo-Carolignan H
No. 1214
C00037915 External link 512 threo-Carolignan K
No. 2166
C00037219 External link 512 Grossamide K
No. 2166
C00036822 External link 512 Boehmenan H
No. 2166
C00037119 External link 512 erythro-Canabisine H
No. 3217
C00042580 External link 512 Hibiscanal
No. 3761
C00042800 External link 512 o-Hibiscanone
CHEMBL1966764
No. 5895

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000602 C00000659 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000602 C00000659 0 / 1
P14679 Tyrosinase Oxidoreductase C00035142 4 / 2
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00007190 0 / 0
P11387 DNA topoisomerase 1 Isomerase C00002631 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00005189 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00007190 0 / 3
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00007190 5 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00007190 0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00007190 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00007190 0 / 0
O14746 Telomerase reverse transcriptase Enzyme C00005189 5 / 5
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00007190 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#609135 Aplastic anemia O14746
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#608902 Drug metabolism, poor, cyp2d6-related P10635
#613989 Dyskeratosis congenita, autosomal dominant, 2; dkca2 O14746
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#615134 Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 O14746
#601665 Obesity P37231
#614742 Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 O14746
#178500 Pulmonary fibrosis, idiopathic; ipf O14746
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679

KEGG DISEASE (14)

KEGG name UniProt
H00764 Cri du chat syndrome O14746 (related)
H01132 Aplastic anemia (AA) O14746 (related)
H01299 Idiopathic pulmonary fibrosis O14746 (related)
H00022 Bladder cancer O14746 (marker)
H00024 Prostate cancer O14746 (marker)
H00036 Osteosarcoma P08684 (marker)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)