| Organism name | Cupressus lusitanica |
|---|---|
| Genus | Cupressus |
| Family | Cupressaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Hesperocyparis lusitanica |
|---|---|
| Linked NCBI taxonomy ID | 103968 |
| Linked level | species |
| Family in NCBI taxonomy | Cupressaceae |
|---|---|
| ID | 3367 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | Spermatophyta |
|---|---|
| ID | 58024 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00006490
|
Podocarpusflavone A
|
CHEMBL220745
|
C094150
|
2 / 1 / 2 | No. 34 | No. 18 |
|
|
|
C00006460
|
4'-O-Methylcupressuflavone
|
No. 34 | No. 18 |
|
||||
|
C00000609
|
(-)-Arctigenin
|
CHEMBL369142
CHEMBL435734 CHEMBL1966556 |
C071942
|
13 / 7 / 6 | No. 223 | No. 21 |
|
|
|
C00000606
|
(-)-Matairesinol
|
CHEMBL425148
|
C068935
|
1 / 0 / 0 | No. 223 | No. 21 |
|
|
|
C00003062
|
beta-Thujaplicin
|
CHEMBL48310
|
C009479
|
27 / 27 / 50 | No. 1304 | No. 35 |
|
|
|
C00003063
|
gamma-Thujaplicin
|
CHEMBL1275999
|
No. 1304 | No. 35 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000609 C00003062 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000609 C00003062 | 0 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003062 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00003062 | 4 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00003062 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00000609 | 1 / 1 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00003062 | 0 / 0 |
| P22894 | Neutrophil collagenase | M10A | C00003062 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00003062 | 2 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000609 | 0 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003062 | 2 / 3 |
| P43235 | Cathepsin K | C1A | C00006490 | 1 / 2 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00003062 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003062 | 0 / 0 |
| P04278 | Sex hormone-binding globulin | Secreted protein | C00000606 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00003062 | 1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000609 | 2 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00000609 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000609 | 1 / 0 |
| P03956 | Interstitial collagenase | M10A | C00003062 | 0 / 1 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00003062 | 7 / 37 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00003062 | 2 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000609 | 0 / 0 |
| P56817 | Beta-secretase 1 | A1A | C00006490 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000609 | 0 / 0 |
| P08253 | 72 kDa type IV collagenase | M10A | C00003062 | 1 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00003062 | 2 / 2 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00000609 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00003062 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003062 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000609 | 1 / 1 |
| Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | Ste7 | C00000609 | 1 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000609 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003062 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003062 | 0 / 0 |
| P08254 | Stromelysin-1 | M10A | C00003062 | 1 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00003062 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00003062 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003062 | 1 / 1 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00003062 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00003062 | 1 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #615279 | Cardiofaciocutaneous syndrome 3; cfc3 |
Q02750
|
| #114500 | Colorectal cancer; crc |
P18054
P84022 |
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #133239 | Esophageal cancer |
P04637
P18054 |
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #143100 | Huntington disease; hd |
P42858
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
P04637
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #265800 | Pycnodysostosis |
P43235
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00028 | Choriocarcinoma |
P03956
(related)
P04637 (related) P08253 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00273 | Pycnodysostosis |
P43235
(related)
|
| H00425 | Lysosomal cysteine protease deficiencies |
P43235
(related)
|
| H00523 | Noonan syndrome and related disorders |
Q02750
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |