Hypericum geminiflorum

• Index
• Plant Species
• Metabolite list (18)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Hypericum geminiflorum
Genus	Hypericum
Family	Hypericaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Hypericum geminiflorum
Linked NCBI taxonomy ID	860794
Linked level	species

Family

Family in NCBI taxonomy	Hypericaceae
ID	629714

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (18)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00036379	1,3,8-Trihydroxy-2-methoxyxanthone					No. 3	No. 15
C00049558	4-Hydroxy-1,2-dimethoxy-xanthone	CHEMBL2029865				No. 3	No. 15
C00049557	6,7-Dihydroxy-1,3-dimethoxyxanthone					No. 3	No. 15
C00038114	1,5-Dihydroxy-6-methoxyxanthone					No. 3	No. 15
C00038112	1,3,8-Trihydroxy-4-methoxyxanthone					No. 3	No. 15
C00038200	2,3-Dimethoxyxanthone	CHEMBL1434162		14 / 16 / 16		No. 35	No. 15
C00029364	Euxanthone / 1,7-Dihydroxyxanthone	CHEMBL389166	C404221	1 / 0 / 0		No. 76	No. 15
C00038192	1-Hydroxyxanthone	CHEMBL187368	C478872	1 / 1 / 1		No. 76	No. 15
C00039394	Hyperielliptone HD	CHEMBL465510				No. 338
C00039393	Hyperielliptone HC					No. 338
C00038677	Cadensin D	CHEMBL465511				No. 338
C00049588	Gemixanthone A					No. 338
C00039392	Hyperielliptone HB / (-)-Hyperielliptone HB	CHEMBL511791 CHEMBL2023366		1 / 1 / 1		No. 1011
C00014453	Gemichalcone A / 3'-(4-Feruloyloxy-3-methylbutyl-2(Z)-enyl)-4,2',4'-trihydroxychalcone	CHEMBL2164984 CHEMBL2164987				No. 1706
C00014483	Gemichalcone C / 3'-(4-Feruloyloxy-3-methylbutyl-2(Z)-enyl)-2,4,2',4'-tetrahydroxychalcone	CHEMBL463638 CHEMBL499860		1 / 2 / 2		No. 1706
C00014451	Isogemichalcone B / 3'-(4-Coumaroyloxy-3-methylbutyl-2(E)-enyl)-4,2',4'-trihydroxychalcone	CHEMBL497716 CHEMBL517334		2 / 0 / 3		No. 1706
C00014452	Gemichalcone B / 3'-(4-Coumaroyloxy-3-methylbutyl-2(Z)-enyl)-4,2',4'-trihydroxychalcone	CHEMBL497716 CHEMBL517334		2 / 0 / 3		No. 1706
C00039391	Hyperielliptone HA / (-)-Hyperielliptone HA					No. 7669

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00014451 C00014452	0 / 3
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00014451 C00014452	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00038200	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00038200	4 / 2
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00039392	1 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00038192	1 / 1
P35610	Sterol O-acyltransferase 1	Enzyme	C00029364	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00038200	2 / 2
P39748	Flap endonuclease 1	Enzyme	C00038200	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00038200	0 / 0
P04062	Glucosylceramidase	Enzyme	C00038200	6 / 4
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00014483	2 / 2
O15118	Niemann-Pick C1 protein	Unclassified protein	C00038200	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00038200	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00038200	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00038200	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00038200	0 / 0
O00255	Menin	Unclassified protein	C00038200	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00038200	1 / 2
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00038200	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions