| Organism name | Rheum maximowiczii |
|---|---|
| Genus | Rheum |
| Family | Polygonaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Rheum |
|---|---|
| Linked NCBI taxonomy ID | 3620 |
| Linked level | genus |
| Family in NCBI taxonomy | Polygonaceae |
|---|---|
| ID | 3615 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00015300
|
Resveratroloside
/ Resveratrol 4'-O-beta-D-glucopyranoside / 3,4',5-Trihydroxystilbene 4'-O-beta-D-glucopyranoside |
CHEMBL478753
CHEMBL476674 |
No. 36 | No. 13 |
|
|||
|
C00037422
|
Lindleyin
|
C018585
|
No. 36 | No. 13 |
|
|||
|
C00019420
|
Physcion
/ 1,8-Dihydroxy-3-methyl-6-methoxyanthraquinone |
CHEMBL42624
|
C008905
|
18 / 20 / 14 | 1 / 0 | No. 41 | No. 62 |
|
|
C00030192
|
(+)-Betuloside
/ Epirhododendrin |
CHEMBL1086682
|
No. 45 | No. 72 |
|
|||
|
C00032938
|
Emodin-8-O-D-glucopyranoside
/ 8-O-beta-D-glucopyranosyl emodin / Emodin 8-O-beta-D-glucopyranoside |
CHEMBL464360
|
2 / 1 / 1 | No. 568 | No. 62 |
|
||
|
C00037918
|
Torachrysone
|
CHEMBL2204398
|
No. 3003 |
|
||||
|
C00029306
|
(+)-Rhododendrol
|
CHEMBL108014
CHEMBL1086681 CHEMBL1778763 |
1 / 0 / 0 | No. 4115 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q92731 | Estrogen receptor beta | NR3A2 | C00019420 C00032938 | 0 / 1 |
| P03372 | Estrogen receptor | NR3A1 | C00019420 C00032938 | 1 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00019420 | 2 / 2 |
| P08246 | Neutrophil elastase | S1A | C00019420 | 2 / 1 |
| P08311 | Cathepsin G | S1A | C00019420 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00029306 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00019420 | 0 / 0 |
| Q9H244 | P2Y purinoceptor 12 | Purine receptor | C00019420 | 1 / 1 |
| P06280 | Alpha-galactosidase A | Enzyme | C00019420 | 1 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00019420 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00019420 | 2 / 3 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00019420 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00019420 | 4 / 3 |
| O43451 | Maltase-glucoamylase, intestinal | Hydrolase | C00019420 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00019420 | 0 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00019420 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00019420 | 0 / 0 |
| P09619 | Platelet-derived growth factor receptor beta | Pdgfr | C00019420 | 5 / 1 |
| P16234 | Platelet-derived growth factor receptor alpha | Pdgfr | C00019420 | 2 / 1 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00019420
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #615007 | Basal ganglia calcification, idiopathic, 4; ibgc4 |
P09619
|
| #609821 | Bleeding disorder, platelet-type, 8; bdplt8 |
Q9H244
|
| #162800 | Cyclic neutropenia |
P08246
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #606764 | Gastrointestinal stromal tumor; gist |
P16234
|
| #607685 | Hypereosinophilic syndrome, idiopathic; hes |
P16234
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #607785 | Juvenile myelomonocytic leukemia; jmml |
P09619
|
| #601626 | Leukemia, acute myeloid; aml |
P09619
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #131440 | Myeloproliferative disorder, chronic, with eosinophilia |
P09619
|
| #228550 | Myofibromatosis, infantile, 1; imf1 |
P09619
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00026 | Endometrial Cancer |
P03372
(marker)
Q92731 (marker) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00042 | Glioma |
P09619
(related)
P16234 (related) |
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H01235 | Bleeding disorder platelet-type |
Q9H244
(related)
|